Search Results (275)

With accelerating global urbanization and increasingly diverse demands for public spaces, promoting urban low-carbon transitions and enhancing residents’ quality of life have become central missions of modern urban development. As one of the city’s primary arteries, streets—through their green landscapes, slow-moving transportation systems, and public facilities—play an indispensable role in reducing carbon emissions, promoting healthy living, and improving residents’ well-being. In this study, the Yubei District of Chongqing was selected as the research area, and an automated evaluation framework was proposed for street visual quality, based on multi-source street view data and ensemble learning. PSP-Net semantic segmentation model was employed to extract eight key visual indicators from street view images, including green view index, Visual Entropy (Entropy), sky view factor (SVF), drivable space, sidewalk, safety facilities, buildings, and enclosure. Based on these features, a Stacking-based ensemble learning model was constructed, integrating multiple base models such as Random Forest, XGBoost, and LightGBM, with Linear Regression as the meta-learner, to predict street visual quality. The results demonstrate that the ensemble model significantly outperforms any single model, achieving a correlation coefficient (r) of 0.77 and effectively capturing the complex perceptual features of street environments. This study provides a reliable, intelligent, and quantitative method for large-scale evaluation of urban street visual quality, while supplying data support and decision-making references for street renewal and spatial optimization. Full article

Background: Genome-scale metabolic models (GEMs) are foundational tools for systems biology, enabling quantitative interrogation of human metabolism across physiological and pathological states. However, many legacy reconstructions exhibit heterogeneous identifier usage, incomplete pathway integration, and limited thermodynamic refinement, constraining reproducibility, interoperability, and translational applicability. Methods: We present EHMN 2026, an update of the Edinburgh Human Metabolic Network. The reconstruction was refined through systematic identifier reconciliation using MetaNetX and ChEBI mappings, duplicate reaction consolidation, thermodynamic directionality assessment, and structured pathway annotation via Reactome. The final model was encoded in Systems Biology Markup Language (SBML) Level 3 Version 2 with the Flux Balance Constraints (FBC2) package, ensuring explicit gene–protein–reaction (GPR) representation and compatibility with modern constraint-based modelling toolchains. Results: EHMN 2026 comprises 11 compartments, 14,321 metabolites (species), and 22,642 reactions, supported by 3996 gene products. Of all reactions, 9638 (42.6%) contain GPR associations, linking metabolic transformations to 2887 unique Ensembl gene identifiers (ENSG). Pathway integration yielded 2194 unique Reactome identifiers, providing structured pathway-level organisation of metabolic functions. Thermodynamic refinement reduced infeasible energy-generating cycles and improved reaction directionality coherence while preserving global network connectivity. The reconstruction is fully SBML-compliant and portable across major modelling platforms. Compared with Recon3D and Human1, EHMN 2026 uniquely combines native Reactome reaction-level annotation, systematic MetaNetX identifier harmonisation, documented thermodynamic cycle elimination (37 cycles, 0 remaining), and an 11-compartment architecture supporting organelle-specific modelling—features designed for QSP and multi-layer integration applications. Conclusions: EHMN 2026 delivers a rigorously harmonised, thermodynamically refined, and pathway-annotated human metabolic reconstruction with enhanced annotation depth and standards-based interoperability. By combining genome-scale coverage with structured gene and pathway integration, the model establishes a robust computational backbone for reproducible metabolic analysis and provides a scalable foundation for future multi-layer systems pharmacology and integrative modelling frameworks. Full article

Background: Proton pump inhibitors (PPIs) are widely used to prevent acid-related complications, yet concerns persist about infectious harm. Observational studies have linked PPIs to Clostridioides difficile infection (CDI) and pneumonia whereas randomized controlled trials (RCTs) consistently show reductions in upper gastrointestinal bleeding. We therefore conducted a systematic review and meta-analysis restricted to randomized controlled trials to evaluate whether PPIs increase the risk of CDI, and to assess pneumonia and gastrointestinal bleeding to contextualize net clinical benefit. Methods: A comprehensive search of randomized controlled trials (RCTs) was conducted using several databases including PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL) and SCOPUS until July 2025. All published English-language RCTs that met the inclusion criteria were included. Random-effects models were utilized to calculate pooled odds ratios (ORs) with 95% confidence intervals. The risk of bias was assessed using the Cochrane Risk of Bias 2.0 Tool, and heterogeneity was quantified using I² statistics. Analysis was performed using STATA version 18 and RevMan 5.3. Results: Across eight RCTs (n = 30,019), PPIs did not increase C. difficile infection versus placebo (OR 1.29, 95% CI 0.82–2.02; p = 0.27; I² = 16%) with leave-one-out (LOO) analyses showing stable estimates. In six trials reporting pneumonia, there was no significant difference between groups (OR 1.00, 95% CI 0.92–1.09; p = 0.99; I² = 0%). For clinically important upper GI bleeding (seven trials), PPIs were associated with a statistically significant lower risk when compared to placebo (OR 0.51, 95% CI 0.27–0.94; p = 0.03; I² = 56%). Conclusions: Across randomized trials with follow-up ranging from 30 days to 3 years, PPI prophylaxis significantly reduced upper gastrointestinal bleeding without increasing the risk of CDI or pneumonia. These findings support the use of PPIs for prophylaxis when clinically indicated, while recognizing that larger trials are needed to better assess rare adverse events. Full article

Financial time series forecasting remains a challenging task due to the high non-stationarity and concept drift inherent to market data. Existing deep learning models, such as LSTMs and transformers, typically employ static weights after training, limiting their ability to adapt to rapid market regime shifts (e.g., from trends to reversals). To bridge this gap between static parameters and dynamic environments, we propose a novel framework named Game-Theoretic HyperNetwork (GTH-Net), which introduces a context-aware meta-learning mechanism to achieve adaptive forecasting. Specifically, we first introduce an Evolutionary Game-Theoretic Correction Module (E-GTCM) to explicitly extract latent buying and selling pressure based on market microstructure priors through an iterative gated evolution process. Subsequently, we propose a HyperNetwork-based fusion mechanism that treats the extracted game state as a meta-context to dynamically generate the weights of the forecasting head. This allows the model to automatically switch its prediction rules in response to shifting market regimes. Extensive experiments on real-world stock datasets demonstrate that GTH-Net significantly outperforms baselines in terms of machine learning predictive accuracy and simulated financial profitability. Furthermore, ablation studies and parameter analysis confirm that the dynamic weight generation mechanism effectively captures market reversals caused by overcrowded trades. Full article

Artificial intelligence (AI)-supported agricultural disease detection has become increasingly important for addressing global food security challenges. In this study, a hybrid meta-heuristic optimization-based feature selection approach is proposed for the detection of peacock eye disease (Venturia oleaginea) on olive leaves. The proposed method combines Artificial Rabbit Optimization (ARO) and Genetic Algorithm (GA) strategies to balance global exploration and local exploitation during feature selection. Comprehensive experiments conducted on a dataset of 954 olive leaf images demonstrate that the proposed approach achieves an F1-score of 99.7% while reducing the feature dimensionality by 95%, selecting only 100 features from ResNet101. Statistical analysis confirms that the method significantly outperforms standalone GA and ARO approaches ($p<0.05$, paired t-tests), demonstrating superior long-term convergence behavior and a 47–56% reduction in performance variance across repeated runs. Compared to existing approaches in the literature, the proposed method attains competitive or superior accuracy with substantially fewer features, indicating a marked reduction in computational complexity. These results suggest that the proposed hybrid feature selection framework has strong potential for deployment in resource-constrained agricultural monitoring scenarios, where efficient inference and reduced model complexity are critical. Full article

Existing research has demonstrated that meta-learning methods hold considerable promise in addressing the challenges posed by few-shot object detection. However, remote sensing scenarios present two major challenges. The sparse features of small objects provide insufficient support information for query enhancement, and significant morphological variations caused by lighting and viewpoint differences hinder intra-class consistency capture via direct alignment in few-shot learning. To address these challenges, we propose a generative meta-learning detection framework. The framework first introduces a Dynamic Relation Dual-Stream Network to achieve dynamic support-query feature alignment through joint modeling of evolutionary and relational features, thereby enhancing representation in few-shot conditions. Second, an Optimal Transport-based Generative Meta-Learner is developed to mitigate feature distribution bias via generative augmentation in latent space. Additionally, an Orthogonal Frequency Decomposition Head is incorporated to adaptively separate query features into low-frequency contour and high-frequency detail components, effectively suppressing background noise interference. Experiments on multiple remote sensing datasets demonstrate that the proposed method achieves consistent performance gains over leading baseline methods in various few-shot settings. Its effectiveness is further validated across different backbone networks, highlighting strong generalization in few-shot remote sensing object detection. Full article

Motor imagery (MI) classification using EEG signals is central to brain–computer interfaces but remains challenging due to low signal-to-noise ratio, non-stationarity, and high inter-subject variability. We introduce EEG-TriNet++, a multi-branch deep learning architecture that enhances both classification accuracy and cross-subject generalization. The model integrates three complementary components: convolutional spatial–spectral encoders for channel-wise and frequency-specific patterns, bidirectional LSTMs to model temporal dynamics, and a Transformer head for global relational reasoning. A patchwise tokenization strategy and neural architecture search optimize the trade-off between efficiency and representational capacity. To address individual differences, a model-agnostic meta-learning (MAML) module enables rapid adaptation to new users with limited data. Evaluated on two public MI datasets under within-subject and leave-one-subject-out (LOSO) protocols, EEG-TriNet++ achieves 79.1% and 78.6% accuracy in within-subject tasks, and 72.4% and 71.3% in LOSO settings. Ablation studies validate the contribution of each module, and comparisons with state-of-the-art methods demonstrate consistent performance gains under identical conditions. Full article

Addressing challenges in few-shot image classification, this study introduces the Multi-Dimensional Attention and Composite Loss Former, a meta-learning model built on a Residual Network-12 backbone. The model incorporates multi-dimensional attention mechanisms and is trained with a composite loss function applied across the entire architecture. It enhances feature extraction by dynamically focusing on critical local and global information, while the composite loss optimizes classification accuracy, emphasizes hard samples, suppresses overfitting, and promotes intra-class feature compactness. Comprehensive experiments conducted on the miniImageNet and tieredImageNet datasets demonstrate that the proposed model achieves superior performance in both meta-training and meta-testing stages compared to existing benchmarks, effectively validating its robustness and generalization capabilities in few-shot learning tasks. Full article

Emotional intelligence (EI) and transformational leadership (TL) have been identified as key factors in team effectiveness (TE); however, the empirical evidence remains fragmented and exhibits substantial conceptual and methodological heterogeneity, particularly in studies that simultaneously integrate these three variables. To address this gap, the present study examined the relationships among TL, EI, and TE by applying the PRISMA 2020 protocol and the PICO-S framework. A total of 728 studies published in Scopus, Web of Science, ScienceDirect, Emerald, ProQuest, and APA PsycNet were identified, of which 22 studies were included in the systematic review and 15 documents in the meta-analysis. The results revealed positive and statistically significant correlations between TL–TE (9 studies, 18 effects, N = 3480; r ≈ 0.45), EI–TE (8 studies, 15 effects, N = 3440; r ≈ 0.41), and EI–TL (4 studies, 6 effects, N = 1955; r ≈ 0.63), with effect sizes and levels of heterogeneity ranging from moderate to high. Additionally, variations in the strength of these relationships were observed according to sample size, year of publication, and methodological quality. In conclusion, EI emerges as a central resource that strengthens TL and, through psychological and relational mechanisms, consistently enhances TE in complex organizational contexts. Full article

Hydrogen is a potential energy carrier for the decarbonization of the heating sector; however, its long-term role remains highly debated. This meta-analysis (2024–early 2025) assesses hydrogen’s potential for domestic heating regarding consumption, costs, and environmental impacts. Current scientific evidence distinguishes between hydrogen use for direct residential heating and its role in integrated energy systems. For residential decarbonization, the literature does not support hydrogen as a primary solution: electrification, especially through heat pumps, remains the most efficient and cost-effective long-term pathway. Direct hydrogen heating faces major thermodynamic and economic barriers, including low conversion efficiency, high Levelized Costs of Energy (LCOE), infrastructure limitations, and challenges in achieving broad social acceptance. Hydrogen’s more strategic value emerges at the system level. Hybrid configurations that combine heat pumps with hydrogen storage show strong potential by using heat pumps to efficiently meet thermal demand while reserving hydrogen for flexible backup and storage. In particular, hydrogen is well suited for long-term seasonal energy storage and grid balancing, enhancing system flexibility and reliability. Its main contribution therefore lies not in direct end-use heating, but in strengthening grid resilience and supporting energy autarky in net-zero scenarios. Hydrogen blending into existing gas networks is widely viewed as a transitional measure to stimulate the hydrogen economy and deliver limited short-term emission reductions, rather than a definitive net-zero solution. Overall, hydrogen’s residential role remains niche, requiring targeted research, development, and large-scale pilot projects to validate competitive applications. Full article

The accuracy of forest canopy height estimation is crucial for forest resource management and ecosystem carbon sequestration. However, existing approaches often face limitations in effectively integrating multisource remote sensing data, feature representation, and model learning strategies. To enhance the prediction performance of the model in complex terrain and multisource data environments, this study comprehensively used ICESat-2/ATLAS photon point clouds, Sentinel-2/MSI multispectral imagery, and SRTM-DEM to construct a remote sensing-driven multisource feature system, which eliminated redundant interference using permutation feature importance analysis. Additionally, a self-attention (SA) mechanism was introduced to strengthen high-dimensional feature representation. Three heterogeneous models, incorporating deep neural network (DNN), extreme gradient boosting (XGBoost), and residual network (ResNet), were independently applied for forest canopy height estimation and were further used as base learners, with a random forest as the meta-learner, and an SA-Blending heterogeneous ensemble model that combines a blending technique with an SA mechanism was proposed to enhance the accuracy of forest canopy height estimation. To evaluate the SA optimization strategy and the role of multisource fusion, this study used the original features, SA-optimized features, and multisource fusion features (i.e., the concatenation and fusion of original features and self-attention mechanism features) as inputs to comprehensively compare the performance of each single model and the integrated model. The results show that: (1) The self-attention mechanism significantly improves the prediction performance of heterogeneous models. Compared with original features inputs, the R² of DNN (SA-Only) and XGBoost (SA-Only) increased to 0.706 and 0.708, respectively, and the RMSE decreased to 1.691 m and 1.613 m. Although the R² for ResNet (SA-Only) decreased slightly to 0.699 and the RMSE increased to 1.712 m, the overall impact was not significant. (2) Under the condition of multisource fusion feature input, DNN+SA, XGBoost+SA, and ResNet+SA all demonstrated higher fitting accuracy and stability, verifying the enhancing effect of the SA mechanism on the association expression of multisource information. (3) The SA-Blending model achieved the best overall performance, with R² of 0.766 and RMSE of 1.510 m. It outperformed individual models and the SA-optimized model in terms of overall accuracy, stability, and robustness. The results can provide technical support for high-precision forest canopy height mapping and are of great significance for ecological monitoring applications. Full article

Background/Objectives: Orthodontically induced root resorption (OIRR) is a well-documented but undesired consequence of orthodontic treatment. This systematic review and meta-analysis aimed to assess the diagnostic performance of artificial intelligence (AI) models applied to cone-beam computed tomography (CBCT) for detecting and quantifying OIRR while evaluating their agreement with manual reference standards and the impact of model architecture, validation design, and quantification strategy. Methods: Comprehensive searches were conducted across PubMed/MEDLINE, Scopus, Web of Science, and EMBASE up to November 2025. Studies were included if they employed AI for OIRR diagnosis using CBCT and reported relevant performance metrics. Following PRISMA guidelines, data were extracted and a random-effect meta-analysis was performed. Subgroup analyses explored the influence of model design and validation. Results: Seven studies were included. Pooled sensitivity from three eligible studies was 0.903 (95% CI: 0.818–0.989), suggesting excellent true positive rates. Specificity ranged from 82% to 98%, and area under the receiver operating characteristic curve values reached up to 0.96 across studies using EfficientNet, U-Net, and other convolutional neural network (CNN)-based architectures. The pooled intraclass correlation coefficient for agreement with manual quantification was 1.000, reflecting near-perfect concordance. Subgroup analyzes showed slightly superior performance in CNN-only models compared to hybrid approaches, and better diagnostic metrics with internal validation. Linear assessments appeared more sensitive to early apical shortening than volumetric methods. Conclusions: AI models applied to CBCT demonstrate excellent diagnostic accuracy and high concordance with expert assessments for OIRR detection. These findings support their potential integration into clinical orthodontic workflows. Full article

This study presents a hybrid analytical framework that enhances project selection by achieving reasonable predictive accuracy through the integration of expert judgment and modern artificial intelligence (AI) techniques. Using an enterprise-level dataset of 10,000 completed software projects with verified real-world statistical characteristics, we develop a three-step architecture for intelligent decision support. First, we introduce an extended Analytic Hierarchy Process (AHP) that incorporates organizational learning patterns to compute expert-validated criteria weights with a consistent level of reliability ($CR=0.04$), and Linear Programming is used for portfolio optimization. Second, we propose a machine learning architecture that integrates expert knowledge derived from AHP into models such as Transformers, TabNet, and Neural Oblivious Decision Ensembles through mechanisms including attention modulation, split criterion weighting, and differentiable tree regularization. Third, the hybrid AHP-Stacking classifier generates a meta-ensemble that adaptively balances expert-derived information with data-driven patterns. The analysis shows that the model achieves 97.5% accuracy, a 96.9% F1-score, and a 0.989 AUC-ROC, representing a 25% improvement compared to baseline methods. The framework also indicates a projected 68.2% improvement in portfolio value (estimated incremental value of USD 83.5 M) based on post factum financial results from the enterprise’s ventures.This study is evaluated retrospectively using data from a single enterprise, and while the results demonstrate strong robustness, generalizability to other organizational contexts requires further validation. This research contributes a structured approach to hybrid intelligent systems and demonstrates that combining expert knowledge with machine learning can provide reliable, transparent, and high-performing decision-support capabilities for project portfolio management. Full article

Wind power plants (WPPs), as large-scale cyber–physical systems (CPSs), have become essential to renewable energy generation but are increasingly exposed to cyber threats. Attacks on supervisory control and data acquisition (SCADA) networks can cause cascading physical and economic impacts. The systematic synthesis of cyber risk analysis methods specific to WPPs and cyber–physical energy systems (CPESs) is a need of the hour to identify research gaps and guide the development of resilient protection frameworks. This study employs a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol to review the state of the art in this area. Peer-reviewed studies published between January 2010 and January 2025 were taken from four major journals using a structured set of nine search queries. After removing duplicates, applying inclusion and exclusion criteria, and screening titles and abstracts, 62 studies were examined for analysis on the basis of a synthesis framework. The studies were classified along three methodological dimensions, qualitative vs. quantitative, model-based vs. data-driven, and informal vs. formal, giving us a unified taxonomy of cyber risk analysis approaches. Among the included studies, 45% appeared to be qualitative or semi-quantitative frameworks such as STRIDE, DREAD, or MITRE ATT&CK; 35% were classified as quantitative or model-based techniques such as Bayesian networks, Markov decision processes, and Petri nets; and 20% adopted data-driven or hybrid AI/ML methods. Only 28% implemented formal verification, and fewer than 10% explicitly linked cyber vulnerabilities to safety consequences. Key research gaps include limited integration of safety–security interdependencies, scarce operational datasets, and inadequate modelling of environmental factors in WPPs. This systematic review highlights a predominance of qualitative approaches and a shortage of data-driven and formally verified frameworks for WPP cybersecurity. Future research should prioritise hybrid methods that integrate formal modelling, synthetic data generation, and machine learning-based risk prioritisation to enhance resilience and operational safety of renewable-energy infrastructures. Full article

Contemporary neural and generative architectures are deficient in self-preservation mechanisms and sustainable stability. In uncertain or noisy situations, they frequently demonstrate oscillatory learning, overconfidence, and structural deterioration, indicating a lack of biological regulatory principles in artificial systems. We present Bio-RegNet, a meta-homeostatic Bayesian neural network architecture that integrates T-regulatory-cell-inspired immunoregulation with autophagic structural optimization. The model integrates three synergistic subsystems: the Bayesian Effector Network (BEN) for uncertainty-aware inference, the Regulatory Immune Network (RIN) for Lyapunov-based inhibitory control, and the Autophagic Optimization Engine (AOE) for energy-efficient regeneration, thereby establishing a closed energy–entropy loop that attains adaptive equilibrium among cognition, regulation, and metabolism. This triadic feedback achieves meta-homeostasis, transforming learning into a process of ongoing self-stabilization instead of static optimization. Bio-RegNet routinely outperforms state-of-the-art dynamic GNNs across twelve neuronal, molecular, and macro-scale benchmarks, enhancing calibration and energy efficiency by over 20% and expediting recovery from perturbations by 14%. Its domain-invariant equilibrium facilitates seamless transfer between biological and manufactured systems, exemplifying a fundamental notion of bio-inspired, self-sustaining intelligence—connecting generative AI and biomimetic design for sustainable, living computation. Bio-RegNet consistently outperforms the strongest baseline HGNN-ODE, improving ARI from 0.77 to 0.81 and NMI from 0.84 to 0.87, while increasing equilibrium coherence $\kappa$ from 0.86 to 0.93. Full article