Search Results (18)

Enhancing the livelihood environment for fishermen’s communities with the rapid technological growth is essential in the marine sector. Among the various issues in the fishing industry, fishing zone identification and fish catch detection play a significant role in the fishing community. In this work, the automated prediction of potential fishing zones and classification of fish species in an aquatic environment through machine learning algorithms is developed and implemented. A prototype of the boat structure is designed and developed with lightweight wooden material encompassing all necessary sensors and cameras. The functions of the unmanned boat (FishID-AUV) are based on the user’s control through a user-friendly mobile/web application (APP). The different features impacting the identification of hotspots are considered, and feature selection is performed using various classifier-based learning algorithms, namely, Naive Bayes, Nearest neighbors, Random Forest and Support Vector Machine (SVM). The performance of classifications are compared. From the real-time results, it is clear that the Naive Bayes classification model is found to provide better accuracy, which is employed in the application platform for predicting the potential fishing zone. After identifying the first catch, the species are classified using an AlexNet-based deep Convolutional Neural Network. Also, the user can fetch real-time information such as the status of fishing through live video streaming to determine the quality and quantity of fish along with information like pH, temperature and humidity. The proposed work is implemented in a real-time boat structure prototype and is validated with data from sensors and satellites. Full article

In the contemporary automobile scene, environmental effect abatement is being increasingly sought; this demands a full rethinking of the entire system and entails more than just the reduction in exhaust pollutant emissions. Currently, the most popular approach is the electrification of automobiles, which significantly reduces pollution in major urban areas while simultaneously posing a new set of problems. The two types of zero-emission vehicles that are now being developed the most are hydrogen fuel cells and battery electric cars, but another option is the Hydrogen Internal Combustion Engine (HYICE) engine, which is highly advantageous in terms of pollutants, aside from Nitrogen Oxides (NOx), which can be considerably decreased. The purpose of this study is to develop a novel vehicle design that transports this type of technology into a sporting context while striving for considerable environmental benefits and integrating them into a society where the love of automobiles still has a strong following. The cutting-edge Industrial Design Structure (IDeS) methodology is used in this work, and a sample structure was created to demonstrate how the problems and technical limitations represented can be solved. The steps of the methodology are followed to shape the final product, with careful consideration given to the design of the styling component through the use of the Stylistic Design Engineering (SDE) method. With the ultimate goal of achieving sustainable driving pleasure, the study looks into whether recyclable materials can be used for the body and whether extremely light materials can be used for the chassis. Full article

The development of new approaches for the synthesis of new bioactive heterocyclic derivatives is of the utmost importance for pharmaceutical industry. In this regard, the present study reports the green synthesis of new benzaldazine and ketazine derivatives via the condensation of various carbonyl compounds (aldehydes and ketones with the 3-(1-hydrazineylideneethyl)-1H-indole using the grinding method with one drop of acetic acid). Various spectroscopic techniques were used to identify the structures of the synthesized derivatives. Furthermore, the anticancer activities of the reported azine derivatives were evaluated against colon, hepatocellular, and breast carcinoma cell lines using the MTT technique with doxorubicin as a reference medication. The findings suggested that the synthesized derivatives exhibited potential anti-tumor activities toward different cell lines. For example, 3c, 3d, 3h, 9, and 13 exhibited interesting activity with an IC₅₀ value of 4.27–8.15 µM towards the HCT-116 cell line as compared to doxorubicin (IC₅₀ = 5.23 ± 0.29 µM). In addition, 3c, 3d, 3h, 9, 11, and 13 showed excellent cytotoxic activities (IC₅₀ = 4.09–9.05 µM) towards the HePG-2 cell line compared to doxorubicin (IC₅₀ = 4.50 ± 0.20 µM), and 3d, 3h, 9, and 13 demonstrated high potency (IC₅₀ = 6.19–8.39 µM) towards the breast cell line (MCF-7) as compared to the reference drug (IC₅₀ = 4.17 ± 0.20 µM). The molecular interactions between derivatives 3a-h, 7, 9, 11, 13, and the CDK-5 enzyme (PDB ID: 3IG7) were studied further using molecular docking indicating a high level of support for the experimental results. Furthermore, the drug-likeness analysis of the reported derivatives indicated that derivative 9 (binding affinity = −8.34 kcal/mol) would have a better pharmacokinetics, drug-likeness, and oral bioavailability as compared to doxorubicin (−7.04 kcal/mol). These results along with the structure–activity relationship (SAR) of the reported derivatives will pave the way for the design of additional azines bearing indole with potential anticancer activities. Full article

Globally, manufacturing ecosystems are facing the challenge of twin transition, i.e., how to utilize digitalization for improving or transforming the sustainability of manufacturing operations. Here, operations refer widely to the upstream of manufacturing, while the entire product lifecycle also covers the downstream and end-of-life operations. Here, sustainability is understood to consider the impact of the product lifecycle at environmental, social, and governance (ESG) levels. In this article, we explore this progress through the digitalization concept of business-to-business data sharing, and through one example of a manufacturing ecosystem in Finland. We discuss the federated data space concept and the international data spaces (IDS) architecture as technological building blocks of twin transition, and report the first results from an industry−research shared-risk project. Semi-structured interviews and a diary-style reporting from an industry−research IDS proof-of-concept (PoC) experiment are presented and analyzed within a design science research method framework. The findings give the first indications that while data sharing is seen as important and increasing in relevance in industry, it is currently challenging for companies to see how an open standard architecture creates value beyond a single limited ecosystem view. We also highlight possible avenues for further research. Full article

Outbreaks of hydropericardium hepatitis syndrome caused by fowl adenovirus serotype 4 (FAdV-4) with a novel genotype have been reported in China since 2015, with significant economic losses to the poultry industry. Fiber2 is one of the important structural proteins on FAdV-4 virions. In this study, the C-terminal knob domain of the FAdV-4 Fiber2 protein was expressed and purified, and its trimer structure (PDB ID: 7W83) was determined for the first time. A series of affinity peptides targeting the knob domain of the Fiber2 protein were designed and synthesized on the basis of the crystal structure using computer virtual screening technology. A total of eight peptides were screened using an immunoperoxidase monolayer assay and RT-qPCR, and they exhibited strong binding affinities to the knob domain of the FAdV-4 Fiber2 protein in a surface plasmon resonance assay. Treatment with peptide number 15 (P15; WWHEKE) at different concentrations (10, 25, and 50 μM) significantly reduced the expression level of the Fiber2 protein and the viral titer during FAdV-4 infection. P15 was found to be an optimal peptide with antiviral activity against FAdV-4 in vitro with no cytotoxic effect on LMH cells up to 200 μM. This study led to the identification of a class of affinity peptides designed using computer virtual screening technology that targeted the knob domain of the FAdV-4 Fiber2 protein and may be developed as a novel potential and effective antiviral strategy in the prevention and control of FAdV-4. Full article

Recent analysis has shown deteriorating traffic conditions in urban areas, caused by an increase in the motorization rate, which has risen to 66.6 vehicles per 100 inhabitants. As a result of the pandemic, individuality has grown, hence private vehicles are becoming more prevalent whilst public transport and sharing are negatively affected. Therefore, European policies have encouraged and innovated more sustainable mobility. Thus, the developed project aims to achieve more efficient mobility and more sustainable environments, towards social and economic well-being. The proposed means of transport aims to appeal to an audience with a reduced ability to drive a car as intended. The IDeS methodology was applied to develop a self-driving, urban micro mobility vehicle, aimed to give enough room and equipment for people with moving disabilities. The innovation of the IDeS method is state-of-the-art and ought to satisfy current product needs, which leads to an innovative micromobility vehicle and portrays a design for a car that will help to close the gaps in urban mobility. These design processes, which are distinguished by the fusion of several industrial techniques, enabled the development of a plan that addresses current mobility issues for disabled people and opens to new mobility prospects. Full article

This case study aims to develop a new innovative SUV (Sport Utility Vehicle) model exploiting IDeS (Industrial Design Structure), which is an engineering approach conceived to optimize car design projects in the automotive industry like never before. A compact SUV was chosen because it is a type of vehicle that is highly requested by customers, and it is extremely successful in the market due to its versatility. In fact, compact SUVs are mixed vehicles that combine the pragmatism of a car with the typical robustness of an off-road vehicle making them suitable both for urban and off-road scenarios. The following pages will illustrate the steps followed for the realization of the final product using the SDE (Stylistic Design Engineering) method and other various design technologies, such as Quality Function Deployment (QFD), Benchmarking (BM) and Top Flop Analysis (TPA). In the final part of this project, the virtual prototyping of the product is carried out using Additive Manufacturing (AM) with an FDM 3D printer. The combination of these methods forms, to all intents and purposes, the IDeS, a newly developed innovative and cutting-edge discipline capable of schematically guiding the new product development process in companies with unprecedented efficiency. Full article

This study is on the conception of the DS700 HYBRID project by the application of the Industrial Design Structure method (IDeS), which applies different tools sourced from engineering and style departments, including QFD and SDE, used to create the concept of a hybrid motorbike that could reach the market in the near future. SDE is an engineering approach for the design and development of industrial design projects, and it finds important applications in the automotive sector. In addition, analysis tools such as QFD, comprising benchmarking and top-flop analysis are carried out to maximize the creative process. The key characteristics of the bike and the degree of innovation are identified and outlined, the market segment is identified, and the stylistic trends that are most suitable for a naked motorbike of the future are analyzed. In the second part the styling of each superstructure and of all the components of the vehicle is carried out. Afterwards the aesthetics and engineering perspectives are accounted for to complete the project. This is achieved with modelling and computing tools such as 3D CAD, visual renderings, and FEM simulations, and virtual prototyping thanks to augmented reality (AR), and finally physical prototyping with the use of additive manufacturing (AM). The result is a product conception able to compete in the present challenging market, with a design that is technically feasible and also reaches new lightness targets for efficiency. Full article

In this paper, industrial design structure (IDeS) is applied for the development of two new full-electric sports sedan car proposals that go by the names Blitz Vision AS and Retro. With a deep analysis of the trends dominating the automotive industry, a series of product requirements was identified using quality function deployment (QFD). The results of such analysis led to the definition of the technical specifications of the product via benchmarking (BM) and top-flop analysis (TFA). The product architecture was then defined by making use of a modular platform chassis capable of housing a variety of vehicle bodyworks. The structured methodology of stylistic design engineering (SDE) was used. This can be divided in six phases: (1) stylistic trends analysis; (2) sketches; (3) 2D CAD drawings; (4) 3D CAD models; (5) virtual prototyping; (6) solid stylistic model. The chassis of the CAD model was verified structurally by means of FEM analysis, whereas the drag coefficients of the two vehicle proposals were compared with one of the main competitor’s vehicles via CFD simulations. The resulting car models are both aesthetically appealing and can be further developed, leading eventually to the production stage. This proves the effectiveness of IDeS and SDE in car design. Full article

The present study was set to validate two different suburban-type sportscar bodies with shared common underpinnings. The chosen method to develop this project was the Industrial Design Structure (IDeS), which characterizes the ability to use the different innovative techniques known within the industrial field, across the whole organization. This method is embodied by following a series of structured analysis tools, such as QFD (Quality Function Deployment), Benchmarking (BM), Top-Flop analysis (TFA), Stylistic Design Engineering (SDE), Prototyping, Testing, Budgeting and Planning. This project aims to study the present-day car market and to foresee deployment in the near future. This attempt was confirmed by delivering the complete styling and technical feasibility characteristics of two different sports cars, obtained by the IDeS methodology. This approach of embodying design together with phases of product development would provide a better engineered, target-oriented product, that uses state-of-the-art style and CAD environments to reduce product development time and, hence, overall Time to Market (TTM). Full article

The evolution of innovative and systematic design methodologies over time has widened the design concept involvement from the product development phase, which also includes the production and start-up phases. Literature findings have presented to accomplish a Generative Design (GD) approach through the application of an innovative method called Industrial Structure Design (IDeS), a systematic design method able to discover the customer’s needs and the fundamental technical solutions to obtain a good innovative product, involving the whole organization for this achievement. Nevertheless, there is a social demand for solutions to the dramatic and growing problem of marine pollution from plastic materials, encouraging the designers to conceive a new innovative drone for waste collection at sea. Therefore, this study aims to merge all the most advanced design technologies with IDeS in an integrated way, by generating a structure that can also be adopted to plan the organization of a production company. The approach is validated with the design of the Recovery Plastic Drone (RPD) obtained with the IDeS methodology, combining Design and Product development phases, leading to a better and innovative solution for the market. Full article

The present study is designed to evaluate the effect of infrared assisted spouted bed drying (IR-SBD) on the product quality and energy consumption of whole peanut fruits (including peanut kernels and shells). The dehydration of whole peanuts by means of hot-air drying (HD) and infrared drying (ID) were used as the control groups, and the drying characteristics, energy consumption, microstructure, porosity, hardness and fatty acid content were compared. The results showed that, compared to HD and ID, IR-SBD could reduce the drying time by 40% and 33%, respectively, and reduced energy consumption by 66% and 32%, respectively. During the drying process, the structures of both the peanut shells and peanut kernels underwent significant deformation; specifically, the porosity gradually increased gradually. The maximum porosity value was obtained by the samples dried by means of IR-SBD. Under the three drying conditions, the hardness of the peanut shells first decreased and then increased, while the hardness of the peanut kernels showed a trend of first increasing, then decreasing and finally increasing. Compared to the fresh whole peanuts, the IR-SBD dried samples exhibited a 4.07% decrease in fatty acid. This study shows that IR-SBD is a suitable application for the dehydration process of whole peanuts for the purposes of achieving high-efficiency and -quality production in the industrial sector. Full article

In this research article, an organic polymer based polypyrrole (Ppy) composite material has been synthesized and analyzed for the design and fabrication purposes of a fast-responsive, highly sensitive, and an economical resistive-type novel humidity detection sensor. This humidity sensor most suitably serves the purpose for industrial humidity (i.e., values ranging from low to high) detection applications. First, a polypyrrole composite material (a mixture of polypyrrole, polypyrrole-NiO, polypyrrole-CeO₂, and polypyrrole-Nb₂O₅) has been synthesized by chemical oxidative polymerization method, and then is treated at various temperatures, i.e., 100, 150 and 200 °C, respectively. After this treatment, the synthesized samples were then characterized by using FTIR, SEM, and DTA/TGA techniques for analyzing humidity sensing properties. The polypyrrole samples with the best morphological structure and properties were then incorporated on interdigitated electrodes. For the fabrication purposes of this thin film structure, at first a few drops of polyvinyl alcohol (PVA) were placed over interdigitated electrodes (IDE) and then the synthesized polypyrrole composite was uniformly deposited in the form of a thin film over it. The plots show that this is a good resistive-type humidity detection device for the relative humidity range of 30% to 90%. The response and recovery times of this newly fabricated humidity sensor were reported to be the same as 128 s at room temperature. Additionally, the stability and the repeatability response behavior of this Ppy sensor were verified up to five cycles of multiple repetitions. This presents an excellent stability and repeatability performance of the sensor. Furthermore, the capacitances versus humidity response and recovery properties of the designed sensor were studied too. This illustrates an excellent capacitive verses humidity response and shows a linear and an active behavior. Lastly, the experimental result proves that polypyrrole composite thin film shows a reasonable best performance up to a temperature of 100 °C. Full article

The present study aims to validate a new research method called IDeS (industrial design structure) through the design of an electric bicycle for everyday city life. IDeS is the latest evolution of a combination of innovative and advanced systematic approaches that are used to set a new industrial project. The IDeS methodology is sequentially composed of quality function deployment (QFD), benchmarking (BM), top-flop analysis (TFA), stylistic design engineering (SDE), design for X, prototyping and testing, budgeting, and planning. The present work illustrates how to integrate the abovementioned design methods and achieve a convincing result. In going through the IDeS method step by step, we compare the different solutions on the market in order to understand which are the best performing products and to understand what is missing on the market. This method allowed us to design a bicycle that is as close as possible to the “ideal bike”, obtained with the top/flop analysis. Full article

The present study wants to bring to light a new type of crutch designed for a chronic patient with perennial limited mobility, who must use this support every time a move is needed. The main purpose of the project consists in recommending a correct use of the crutch through technology, limiting the damage normally caused by a bad use of crutches and giving a support both for the patient and for the doctor. All of the features of the crutches were defined through relationship matrices and a benchmarking, which helped us for defining the requirements; other important features were defined, taking a look to the technological progresses applied to new, patented crutches. The result is a sensorized crutch, functional and oriented to meet the user’s needs in order to prevent an incorrect use of the support avoiding the growth of other pains. Full article