Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (41)

Search Parameters:
Keywords = DD fusion

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
22 pages, 24173 KiB  
Article
ScaleViM-PDD: Multi-Scale EfficientViM with Physical Decoupling and Dual-Domain Fusion for Remote Sensing Image Dehazing
by Hao Zhou, Yalun Wang, Wanting Peng, Xin Guan and Tao Tao
Remote Sens. 2025, 17(15), 2664; https://doi.org/10.3390/rs17152664 - 1 Aug 2025
Viewed by 154
Abstract
Remote sensing images are often degraded by atmospheric haze, which not only reduces image quality but also complicates information extraction, particularly in high-level visual analysis tasks such as object detection and scene classification. State-space models (SSMs) have recently emerged as a powerful paradigm [...] Read more.
Remote sensing images are often degraded by atmospheric haze, which not only reduces image quality but also complicates information extraction, particularly in high-level visual analysis tasks such as object detection and scene classification. State-space models (SSMs) have recently emerged as a powerful paradigm for vision tasks, showing great promise due to their computational efficiency and robust capacity to model global dependencies. However, most existing learning-based dehazing methods lack physical interpretability, leading to weak generalization. Furthermore, they typically rely on spatial features while neglecting crucial frequency domain information, resulting in incomplete feature representation. To address these challenges, we propose ScaleViM-PDD, a novel network that enhances an SSM backbone with two key innovations: a Multi-scale EfficientViM with Physical Decoupling (ScaleViM-P) module and a Dual-Domain Fusion (DD Fusion) module. The ScaleViM-P module synergistically integrates a Physical Decoupling block within a Multi-scale EfficientViM architecture. This design enables the network to mitigate haze interference in a physically grounded manner at each representational scale while simultaneously capturing global contextual information to adaptively handle complex haze distributions. To further address detail loss, the DD Fusion module replaces conventional skip connections by incorporating a novel Frequency Domain Module (FDM) alongside channel and position attention. This allows for a more effective fusion of spatial and frequency features, significantly improving the recovery of fine-grained details, including color and texture information. Extensive experiments on nine publicly available remote sensing datasets demonstrate that ScaleViM-PDD consistently surpasses state-of-the-art baselines in both qualitative and quantitative evaluations, highlighting its strong generalization ability. Full article
Show Figures

Figure 1

17 pages, 2200 KiB  
Article
Visual Place Recognition Based on Dynamic Difference and Dual-Path Feature Enhancement
by Guogang Wang, Yizhen Lv, Lijie Zhao and Yunpeng Liu
Sensors 2025, 25(13), 3947; https://doi.org/10.3390/s25133947 - 25 Jun 2025
Viewed by 388
Abstract
Aiming at the problem of appearance drift and susceptibility to noise interference in visual place recognition (VPR), we propose DD–DPFE: a Dynamic Difference and Dual-Path Feature Enhancement method. Embedding differential attention mechanisms in the DINOv2 model to mitigate the effects of process interference [...] Read more.
Aiming at the problem of appearance drift and susceptibility to noise interference in visual place recognition (VPR), we propose DD–DPFE: a Dynamic Difference and Dual-Path Feature Enhancement method. Embedding differential attention mechanisms in the DINOv2 model to mitigate the effects of process interference and adding serial-parallel adapters allows efficient model parameter migration and task adaptation. Our method constructs a two-way feature enhancement module with global–local branching synergy. The global branch employs a dynamic fusion mechanism with a multi-layer Transformer encoder to strengthen the structured spatial representation to cope with appearance changes, while the local branch suppresses the over-response of redundant noise through an adaptive weighting mechanism and fuses the contextual information from the multi-scale feature aggregation module to enhance the robustness of the scene. The experimental results show that the model architecture proposed in this paper is an obvious improvement in different environmental tests. This is most obvious in the simulation test of a night scene, verifying that the proposed method can effectively enhance the discriminative power of the system and its anti-jamming ability in complex scenes. Full article
(This article belongs to the Section Electronic Sensors)
Show Figures

Figure 1

13 pages, 4280 KiB  
Article
Performance Characteristics of the Battery-Operated Silicon PIN Diode Detector with an Integrated Preamplifier and Data Acquisition Module for Fusion Particle Detection
by Allan Xi Chen, Benjamin F. Sigal, John Martinis, Alfred YiuFai Wong, Alexander Gunn, Matthew Salazar, Nawar Abdalla and Kai-Jian Xiao
J. Nucl. Eng. 2025, 6(2), 15; https://doi.org/10.3390/jne6020015 - 15 May 2025
Viewed by 679
Abstract
We present the performance and application of a commercial off-the-shelf Si PIN diode (Hamamatsu S14605) as a charged particle detector in a compact ion beam system (IBS) capable of generating D–D and p–B fusion charged particles. This detector is inexpensive, widely available, and [...] Read more.
We present the performance and application of a commercial off-the-shelf Si PIN diode (Hamamatsu S14605) as a charged particle detector in a compact ion beam system (IBS) capable of generating D–D and p–B fusion charged particles. This detector is inexpensive, widely available, and operates in photoconductive mode under a reverse bias voltage of 12 V, supplied by an A23 battery. A charge-sensitive preamplifier (CSP) is mounted on the backside of the detector’s four-layer PCB and powered by two ±3 V lithium batteries (A123). Both the detector and CSP are housed together on the vacuum side of the IBS, facing the fusion target. The system employs a CF-2.75-flanged DB-9 connector feedthrough to supply the signal, bias voltage, and rail voltages. To mitigate the high sensitivity of the detector to optical light, a thin aluminum foil assembly is used to block optical emissions from the ion beam and target. Charged particles generate step responses at the preamplifier output, with pulse rise times in the order of 0.2 to 0.3 µs. These signals are recorded using a custom-built data acquisition unit, which features an optical fiber data link to ensure the electrical isolation of the detector electronics. Subsequent digital signal processing is employed to optimally shape the pulses using a CR-RCn filter to produce Gaussian-shaped signals, enabling the accurate extraction of energy information. Performance results indicate that the detector’s baseline RMS ripple noise can be as low as 0.24 mV. Under actual laboratory conditions, the estimated signal-to-noise ratios (S/N) for charged particles from D–D fusion—protons, tritons, and helions—are approximately 225, 75, and 41, respectively. Full article
Show Figures

Graphical abstract

44 pages, 823 KiB  
Review
A Systematic Literature Review of DDS Middleware in Robotic Systems
by Muhammad Liman Gambo, Abubakar Danasabe, Basem Almadani, Farouq Aliyu, Abdulrahman Aliyu and Esam Al-Nahari
Robotics 2025, 14(5), 63; https://doi.org/10.3390/robotics14050063 - 14 May 2025
Cited by 1 | Viewed by 2909
Abstract
The increasing demand for automation has led to the complexity of the design and operation of robotic systems. This paper presents a systematic literature review (SLR) focused on the applications and challenges of Data Distribution Service (DDS)-based middleware in robotics from 2006 to [...] Read more.
The increasing demand for automation has led to the complexity of the design and operation of robotic systems. This paper presents a systematic literature review (SLR) focused on the applications and challenges of Data Distribution Service (DDS)-based middleware in robotics from 2006 to 2024. We explore the pivotal role of DDS in facilitating efficient communication across heterogeneous robotic systems, enabling seamless integration of actuators, sensors, and computational elements. Our review identifies key applications of DDS in various robotic domains, including multi-robot coordination, real-time data processing, and cloud–edge–end fusion architectures, which collectively enhance the performance and scalability of robotic operations. Furthermore, we identify several challenges associated with implementing DDS in robotic systems, such as security vulnerabilities, performance and scalability requirements, and the complexities of real-time data transmission. By analyzing recent advancements and case studies, we provide insights into the potential of DDS to overcome these challenges while ensuring robust and reliable communication in dynamic environments. This paper aims to contribute to the transformative impact of DDS-based middleware in robotics, offering a comprehensive overview of its benefits, applications, and security implications. Our findings underscore the necessity for continued research and development in this area, paving the way for more resilient and intelligent robotic systems that operate effectively in real-world scenarios. This review not only fills existing gaps in the literature but also serves as a foundational resource for researchers and practitioners seeking to leverage DDS in the design and implementation of next-generation robotic solutions. Full article
(This article belongs to the Special Issue Innovations in the Internet of Robotic Things (IoRT))
Show Figures

Figure 1

20 pages, 3955 KiB  
Article
Lightweight Pepper Disease Detection Based on Improved YOLOv8n
by Yuzhu Wu, Junjie Huang, Siji Wang, Yujian Bao, Yizhe Wang, Jia Song and Wenwu Liu
AgriEngineering 2025, 7(5), 153; https://doi.org/10.3390/agriengineering7050153 - 12 May 2025
Viewed by 752
Abstract
China is the world’s largest producer of chili peppers, which occupy particularly important economic and social values in various fields such as medicine, food, and industry. However, during its production process, chili peppers are affected by pests and diseases, resulting in significant yield [...] Read more.
China is the world’s largest producer of chili peppers, which occupy particularly important economic and social values in various fields such as medicine, food, and industry. However, during its production process, chili peppers are affected by pests and diseases, resulting in significant yield reduction due to the temperature and environment. In this study, a lightweight pepper disease identification method, DD-YOLO, based on the YOLOv8n model, is proposed. First, the deformable convolutional module DCNv2 (Deformable ConvNetsv2) and the inverted residual mobile block iRMB (Inverted Residual Mobile Block) are introduced into the C2F module to improve the accuracy of the sampling range and reduce the computational amount. Secondly, the DySample sampling operator (Dynamic Sample) is integrated into the head network to reduce the amount of data and the complexity of computation. Finally, we use Large Separable Kernel Attention (LSKA) to improve the SPPF module (Spatial Pyramid Pooling Fast) to enhance the performance of multi-scale feature fusion. The experimental results show that the accuracy, recall, and average precision of the DD-YOLO model are 91.6%, 88.9%, and 94.4%, respectively. Compared with the base network YOLOv8n, it improves 6.2, 2.3, and 2.8 percentage points, respectively. The model weight is reduced by 22.6%, and the number of floating-point operations per second is improved by 11.1%. This method provides a technical basis for intensive cultivation and management of chili peppers, as well as efficiently and cost-effectively accomplishing the task of identifying chili pepper pests and diseases. Full article
(This article belongs to the Topic Digital Agriculture, Smart Farming and Crop Monitoring)
Show Figures

Figure 1

18 pages, 7828 KiB  
Article
Track-Constrained Dual-Baseline Fusion Algorithm for Parallel Train Integrity Monitoring and Positioning with Reduced Sensitivity on Track Curvature
by Jingheng Shao, Qianru Chen, Hengwei Zhang, Yiping Jiang and Wei Jiang
Electronics 2025, 14(8), 1591; https://doi.org/10.3390/electronics14081591 - 14 Apr 2025
Viewed by 348
Abstract
Conventional methods for train positioning and integrity monitoring are limited by their dependence on trackside infrastructure. This reliance on fixed equipment has prompted the investigation of global navigation satellite systems (GNSSs) as a more efficient alternative. The track-constrained algorithm based on the ‘train [...] Read more.
Conventional methods for train positioning and integrity monitoring are limited by their dependence on trackside infrastructure. This reliance on fixed equipment has prompted the investigation of global navigation satellite systems (GNSSs) as a more efficient alternative. The track-constrained algorithm based on the ‘train head (TH) and train tail (TT)’ double-difference (DD) baseline model (Single DD algorithm) has been applied for positioning and train length monitoring. It has been observed that the coefficient matrix can cause the inflation of the odometer corrections when the difference in track slope at both ends of the train is small. This inflation problem reduces the train positioning accuracy. A dual DD baseline fusion algorithm (Dual DD algorithm) with minimized sensitivity on the difference in track slope is thereby introduced. Furthermore, to validate the status of reference stations, a cross-checking function is utilized. The simulation results demonstrate that with a noise setting of 0.0067 m in carrier phase measurement, the Dual DD algorithm enhances the accuracy of train location estimation by up to 10 times compared to the Single DD algorithm. Meanwhile, the simulation result of train length difference validates the feasibility of the cross-checking function. Full article
(This article belongs to the Special Issue Constellation Satellite Design and Application)
Show Figures

Figure 1

17 pages, 2789 KiB  
Article
The PD1 Molecule May Contribute to Lower Treatment-Free Remission Rates in Patients with Chronic Myeloid Leukemia with the e13a2 Transcript
by Paulina Kwaśnik, Michał Kiełbus, Joanna Zaleska, Dorota Link-Lenczowska, Magdalena Zawada, Hubert Wysogląd, Tomasz Sacha and Krzysztof Giannopoulos
J. Clin. Med. 2025, 14(7), 2304; https://doi.org/10.3390/jcm14072304 - 27 Mar 2025
Viewed by 524
Abstract
Background/Objectives: Chronic myeloid leukemia (CML) is characterized by the presence of the BCR::ABL1 fusion gene, most commonly in the e14a2 or e13a2 variants. Studies show that the transcript type in CML may be important for achieving treatment-free remission (TFR). This study aimed [...] Read more.
Background/Objectives: Chronic myeloid leukemia (CML) is characterized by the presence of the BCR::ABL1 fusion gene, most commonly in the e14a2 or e13a2 variants. Studies show that the transcript type in CML may be important for achieving treatment-free remission (TFR). This study aimed to immunologically characterize CML patients with e13a2 and e14a2 transcripts to search for differences that may contribute to achieving remission in patients after therapy withdrawal. Methods: Using multicolor flow cytometry, we analyzed the differences in the immune system at the time of imatinib discontinuation and the early stage of TFR in fifty-one CML patients with different transcripts. RQ-PCR and ddPCR were used to monitor the dynamics of BCR::ABL1 transcript changes. The patients were grouped using principal component analysis (PCA) based on the percentage of detected immune cells that were classified as populations consistently selected by the MCFS-ID algorithm from randomly selected data. Results: PCA separated CML patients into two groups defined by k-means clustering, indicating significant heterogeneity within the studied population. We found a significant association between Cluster metrics (Cluster 1 and 2) and BCR::ABL1 transcript types (e13a2 or e14a2) (p = 0.003, 95% CI: 0.026–0.595, OR = 0.14, Fisher test). The e13a2 transcript was less frequent in Cluster 2 than in Cluster 1, while e14a2 was more common in Cluster 2. Additionally, patients grouped into Cluster 1 had significantly higher percentages of the PD1 expressing populations cDC PD1+, CD56dimCD16+PD1+, CD8+PD1+, CD4+PD1+, and CD19+PD1+, as identified by the MCFS-ID algorithm, compared to patients in Cluster 2. Conclusions: Our results suggest that immunological differences may be related to the BCR::ABL1 transcript type, which could affect the number of active CML cells represented by the BCR::ABL1 transcript amount and thus may determine molecular recurrence. Full article
(This article belongs to the Section Hematology)
Show Figures

Figure 1

13 pages, 3073 KiB  
Article
Electron Screening in Deuteron–Deuteron Reactions on a Zr Target with Oxygen and Carbon Contamination
by Agata Kowalska, Mateusz Kaczmarski, Konrad Czerski, Rakesh Dubey, Gokul Das Haridas, Mathieu Valat, Natalia Targosz-Ślęczka, Paweł Figiel, Justyna Słowik and Jolanta Baranowska
Materials 2025, 18(6), 1331; https://doi.org/10.3390/ma18061331 - 18 Mar 2025
Cited by 1 | Viewed by 704
Abstract
The electron screening effect is responsible for a significant increase in the nuclear reaction rates in metals at very low energies. This is dependent on the local crystal structure of the metallic target and the occurrence of defects or additional elemental impurities in [...] Read more.
The electron screening effect is responsible for a significant increase in the nuclear reaction rates in metals at very low energies. This is dependent on the local crystal structure of the metallic target and the occurrence of defects or additional elemental impurities in the crystal. Here, we studied the deuteron–deuteron fusion reactions on zirconium targets previously implanted with carbon and oxygen ions. The 2H(d,p)3H reaction yield was measured at two deuteron energies, 8 and 20 keV, in order to determine the strength of the electron screening effect and its dependence on the density of the implanted impurities. We found that carbon implantation strongly reduced the experimentally determined screening energy, while oxygen implantation had the opposite effect. These results are especially important for the application of nuclear fusion in metallic environments at very low energies. Full article
Show Figures

Figure 1

26 pages, 34170 KiB  
Article
Navigating ALICE: Advancements in Deployable Docking and Precision Detection for AUV Operations
by Yevgeni Gutnik, Nir Zagdanski, Sharon Farber, Tali Treibitz and Morel Groper
Robotics 2025, 14(1), 5; https://doi.org/10.3390/robotics14010005 - 31 Dec 2024
Cited by 2 | Viewed by 1650
Abstract
Autonomous Underwater Vehicles (AUVs) operate independently using onboard batteries and data storage, necessitating periodic recovery for battery recharging and data transfer. Traditional surface-based launch and recovery (L&R) operations pose significant risks to personnel and equipment, particularly in adverse weather conditions. Subsurface docking stations [...] Read more.
Autonomous Underwater Vehicles (AUVs) operate independently using onboard batteries and data storage, necessitating periodic recovery for battery recharging and data transfer. Traditional surface-based launch and recovery (L&R) operations pose significant risks to personnel and equipment, particularly in adverse weather conditions. Subsurface docking stations provide a safer alternative but often involve complex fixed installations and costly acoustic positioning systems. This work introduces a comprehensive docking solution featuring the following two key innovations: (1) a novel deployable docking station (DDS) designed for rapid deployment from vessels of opportunity, operating without active acoustic transmitters; and (2) an innovative sensor fusion approach that combines the AUV’s onboard forward-looking sonar and camera data. The DDS comprises a semi-submersible protective frame and a subsurface, heave-compensated docking component equipped with backlit visual markers, an electromagnetic (EM) beacon, and an EM lifting device. This adaptable design is suitable for temporary installations and in acoustically sensitive or covert operations. The positioning and guidance system employs a multi-sensor approach, integrating range and azimuth data from the sonar with elevation data from the vision camera to achieve precise 3D positioning and robust navigation in varying underwater conditions. This paper details the design considerations and integration of the AUV system and the docking station, highlighting their innovative features. The proposed method was validated through software-in-the-loop simulations, controlled seawater pool experiments, and preliminary open-sea trials, including several docking attempts. While further sea trials are planned, current results demonstrate the potential of this solution to enhance AUV operational capabilities in challenging underwater environments while reducing deployment complexity and operational costs. Full article
(This article belongs to the Special Issue Navigation Systems of Autonomous Underwater and Surface Vehicles)
Show Figures

Figure 1

10 pages, 2270 KiB  
Article
Study of the Pure Deuterium Fuel Burning Rate in Z-Pinch Devices with Magneto-Inertial Confinement
by Olzhas Bayakhmetov and Assylkhan Azamatov
Energies 2024, 17(21), 5297; https://doi.org/10.3390/en17215297 - 24 Oct 2024
Viewed by 955
Abstract
The burning rate of pure deuterium (D-D) fuel in Z-pinch devices with magneto-inertial confinement was studied in this paper. The system of particle and energy balance equations for D-D fuel burning with a mixed D-T-3He fusion cycle (D-D, D-T, and D- [...] Read more.
The burning rate of pure deuterium (D-D) fuel in Z-pinch devices with magneto-inertial confinement was studied in this paper. The system of particle and energy balance equations for D-D fuel burning with a mixed D-T-3He fusion cycle (D-D, D-T, and D-3He reactions) was solved numerically, taking into account the densities of all reacted and produced ions (protons, deuterium, tritium, helium-3, and alpha-particles). The obtained results indicate that effective D-D fusion in Z-pinch devices can be successfully achieved under conditions of a hot, dense plasma with an initial temperature of 31 keV or higher. The initial ion density of deuterium and electron density were equal due to quasi-neutrality condition of the plasma, with both reaching 1024 m−3. Although the obtained results show that the burning rate of D-D fuel is approximately 2.3 times slower and its power density notably lower than that of D-T fuel, pure deuterium plasma can be considered as a promising alternative to well-studied deuterium–tritium plasma, with potential future applications in magneto-inertial fusion (MIF) facilities. Full article
(This article belongs to the Section I2: Energy and Combustion Science)
Show Figures

Figure 1

13 pages, 3401 KiB  
Article
Heart Rate Recovery Index and Improved Diastolic Dyssynchrony in Fusion Pacing Cardiac Resynchronization Therapy
by Andra Gurgu, Constantin-Tudor Luca, Cristina Vacarescu, Dan Gaiță, Simina Crișan, Adelina-Andreea Faur-Grigori, Alina-Ramona Cozlac, Cristina Tudoran, Mădălin-Marius Margan and Dragos Cozma
J. Clin. Med. 2024, 13(21), 6365; https://doi.org/10.3390/jcm13216365 - 24 Oct 2024
Cited by 1 | Viewed by 987
Abstract
Background: Restoring electrical synchrony with cardiac resynchronization therapy (CRT) reverses the heart failure phenotype developed by left-ventricular (LV) dyssynchrony. This study aimed to identify new predictors of response to LV-only fusion pacing CRT. Methods: A select group of patients with CRT-P indications received [...] Read more.
Background: Restoring electrical synchrony with cardiac resynchronization therapy (CRT) reverses the heart failure phenotype developed by left-ventricular (LV) dyssynchrony. This study aimed to identify new predictors of response to LV-only fusion pacing CRT. Methods: A select group of patients with CRT-P indications received a right atrium (RA)/LV DDD pacing system. LV dyssynchrony was assessed via offline TDI timing focusing on the temporal difference between peak septal (E″T) and lateral wall (A“T) motion. CRT effectiveness was evaluated at each follow-up, involving the heart rate recovery index (HRRI) parameter (acceleration/deceleration time) derived from exercise testing along with the echocardiographic parameters. Patients were classified into super-responders (SR), responders (R), and non-responders (NR). Results: Baseline initial characteristics: 62 patients (35 male) aged 62 ± 11 y.o. with non-ischemic dilated cardiomyopathy (DCM). Ejection fraction (EF) 27 ± 5.2%; QRS 164 ± 18 ms; 29% had type III diastolic dysfunction (DD), 63% type II DD, and 8% type I DD. Average follow-up was 45 ± 19 months: 34% of patients were SR, 61% R, and 5% NR. The E″T decreased from 90 ± 20 ms to 25 ± 10 ms in SR, with a shorter deceleration time (DT) during exercise test compared to NR (109 ± 68 ms vs. 330 ± 30 ms; p < 0.0001). The responders present a higher HRRI (2.87 ± 1.47 vs. 0.98 ± 0.08; p = 0.03) compared to NR and a significantly decrease in E“T and A“T from 76 ± 13 ms to 51 ± 11 ms (p < 0.0001). Prolonged DT was associated with an accentuated LV dyssynchrony and nonoptimal response to CRT. Conclusions: The study identified new parameters for assessing responsiveness to LV-only fusion pacing CRT, which could improve candidate selection and CRT implementation. Full article
(This article belongs to the Section Cardiology)
Show Figures

Figure 1

15 pages, 1980 KiB  
Article
The Unexplored Role of Mitochondria-Related Oxidative Stress in Diverticular Disease
by Martina Cappelletti, Lucia Pallotta, Rosa Vona, Antonella Tinari, Annalinda Pisano, Giovanni Casella, Daniele Crocetti, Dominga Carlomagno, Ivan Tattoli, Carla Giordano, Paola Matarrese and Carola Severi
Int. J. Mol. Sci. 2024, 25(17), 9680; https://doi.org/10.3390/ijms25179680 - 6 Sep 2024
Viewed by 1583
Abstract
The pathophysiology of diverticular disease (DD) is not well outlined. Recent studies performed on the DD human ex vivo model have shown the presence of a predominant transmural oxidative imbalance whose origin remains unknown. Considering the central role of mitochondria in oxidative stress, [...] Read more.
The pathophysiology of diverticular disease (DD) is not well outlined. Recent studies performed on the DD human ex vivo model have shown the presence of a predominant transmural oxidative imbalance whose origin remains unknown. Considering the central role of mitochondria in oxidative stress, the present study evaluates their involvement in the alterations of DD clinical phenotypes. Colonic surgical samples of patients with asymptomatic diverticulosis, complicated DD, and controls were analyzed. Electron microscopy, protein expression, and cytofluorimetric analyses were performed to assess the contribution of mitochondrial oxidative stress. Functional muscle activity was tested on cells in response to contractile and relaxant agents. To assess the possibility of reverting oxidative damages, N-acetylcysteine was tested on an in vitro model. Compared with the controls, DD tissues showed a marketed increase in mitochondrial number and fusion accompanied by the altered mitochondrial electron transport chain complexes. In SMCs, the mitochondrial mass increase was accompanied by altered mitochondrial metabolic activity supported by a membrane potential decrease. Ulteriorly, a decrease in antioxidant content and altered contraction–relaxation dynamics reverted by N-acetylcysteine were observed. Therefore, the oxidative stress-driven alterations resulted in mitochondrial impairment. The beneficial effects of antioxidant treatments open new possibilities for tailored therapeutic strategies that have not been tested for this disease. Full article
(This article belongs to the Special Issue Oxidative Stress and Antioxidants in Human Diseases)
Show Figures

Figure 1

12 pages, 843 KiB  
Article
Left Atrium Reverse Remodeling in Fusion CRT Pacing: Implications in Cardiac Resynchronization Response and Atrial Fibrillation Incidence
by Cristina Văcărescu, Dragoș Cozma, Simina Crișan, Dan Gaiță, Debora-Delia Anutoni, Mădălin-Marius Margan, Adelina-Andreea Faur-Grigori, Romina Roteliuc, Silvia-Ana Luca, Mihai-Andrei Lazăr, Oana Pătru, Liviu Cirin, Petru Baneu and Constantin-Tudor Luca
J. Clin. Med. 2024, 13(16), 4814; https://doi.org/10.3390/jcm13164814 - 15 Aug 2024
Cited by 1 | Viewed by 1492
Abstract
Background: When compared to biventricular pacing, fusion CRT pacing was linked to a decreased incidence of atrial fibrillation (AF). There is a gap in the knowledge regarding exclusive fusion CRT without interference with RV pacing, and all the current data are based [...] Read more.
Background: When compared to biventricular pacing, fusion CRT pacing was linked to a decreased incidence of atrial fibrillation (AF). There is a gap in the knowledge regarding exclusive fusion CRT without interference with RV pacing, and all the current data are based on populations of patients with intermittent fusion pacing. Purpose: To assess left atrium remodeling and AF incidence in a real-life population of permanent fusion CRT-P. Methods: Retrospective data were analyzed from a cohort of patients with exclusive fusion CRT-P. Device interrogation, exercise testing, transthoracic echocardiography (TE), and customized medication optimization were all part of the six-monthly individual follow-up. Results: Study population: 73 patients (38 males) with non-ischemic dilated cardiomyopathy aged 63.7 ± 9.3 y.o. Baseline characteristic: QRS 159.8 ± 18.2 ms; EF 27.9 ± 5.1%; mitral regurgitation was severe in 38% of patients, moderate in 47% of patients, and mild in 15% of patients; 43% had type III diastolic dysfunction (DD), 49% had type II DD, 8% had type I DD. Average follow-up was 6.4 years ± 27 months: 93% of patients were responders (including 31% super-responders); EF increased to 40.4 ± 8.5%; mitral regurgitation decreased in 69% of patients; diastolic profile improved in 64% of patients. Paroxysmal and persistent AF incidence was 11%, with only 2% of patients developing permanent AF. Regarding LA volume, statistically significant LA reverse remodeling was observed. Conclusions: Exclusive fusion CRT-P was associated with important LA reverse remodeling and a low incidence of AF. Full article
(This article belongs to the Special Issue Clinical Perspectives on Cardiac Electrophysiology and Arrhythmias)
Show Figures

Figure 1

12 pages, 1998 KiB  
Communication
New Mini Neutron Tubes with Multiple Applications
by Ka-Ngo Leung
J. Nucl. Eng. 2024, 5(3), 197-208; https://doi.org/10.3390/jne5030014 - 26 Jun 2024
Cited by 3 | Viewed by 2653
Abstract
Recent experimental investigations have demonstrated that a substantial amount of H/D ions can be formed by thermal desorption processes. Based on these new findings, new mini axial and coaxial-type neutron tubes have been developed for the production of high or [...] Read more.
Recent experimental investigations have demonstrated that a substantial amount of H/D ions can be formed by thermal desorption processes. Based on these new findings, new mini axial and coaxial-type neutron tubes have been developed for the production of high or low-energy neutrons via the d-d, d-10B, d-7Li or p-7Li nuclear reactions. By operating these mini neutron tubes with a high frequency AC high-voltage supply, short pulses of high intensity neutron beams can be generated. Multiple applications, such as carbon and well logging, neutron imaging, cancer therapy, medical isotope production, fission reactor start-up, fusion reactor material evaluation, homeland security and space exploration can be performed with the subcompact neutron generator system. It is shown that the performance of these new mini neutron tubes can exceed those of the conventional plasma-based neutron sources. Full article
Show Figures

Figure 1

11 pages, 1528 KiB  
Article
Theoretical Study of the D-T Fuel Burning Rate in Z-Pinch Facilities with Magneto-Inertial Confinement
by Olzhas Bayakhmetov and Assylkhan Azamatov
Energies 2024, 17(13), 3069; https://doi.org/10.3390/en17133069 - 21 Jun 2024
Cited by 1 | Viewed by 1202
Abstract
This paper focuses on the theoretical study of the burning rate of D-T fuel in Z-pinch devices with magneto-inertial confinement. The investigated nuclear fusion process involved fast laser ignition of a mixed D-T fuel contained in a capsule at a temperature of 10 [...] Read more.
This paper focuses on the theoretical study of the burning rate of D-T fuel in Z-pinch devices with magneto-inertial confinement. The investigated nuclear fusion process involved fast laser ignition of a mixed D-T fuel contained in a capsule at a temperature of 10 keV, influenced by a strong electromagnetic field. The D-T, D-D, D-3He, 3He-3He, and T-T fusion reactions were employed in the calculations. Based on modern experimental fit data of nuclear fusion reaction rates, the particle and energy balance equations, along with their numerical solutions, were considered, utilizing the ion densities of charged particles such as protons, deuterium, tritium, 3He, and 4He ions. The plasma was in a hot, ultra-dense state, under the quasi-neutrality condition, with initial deuterium and tritium densities of 5×1023 cm−3 and an electron density of 10×1023 cm−3. The ion and electron temperatures were considered equal in this paper. The time dependencies of the ion densities, plasma temperature, energy yield from charged ions and neutrons, fusion power density, and bremsstrahlung radiation loss were investigated. Full article
(This article belongs to the Section B4: Nuclear Energy)
Show Figures

Figure 1

Back to TopTop