Search Results (6)

The platelet count, a component of the full blood count, has been identified as a useful diagnostic marker for cancer in primary care. The reference range for the platelet count is 150 to 400 or 450 × 10⁹/L; this range does not account for natural variation in platelet count by age and sex. This study used three primary care cohorts from England, Canada, and Australia. Patients aged 40 years and over with a full blood count were included and stratified by age (in 10-year bands), sex, (male/female), and platelet count group. Cancer incidence within one year of the test date was estimated from linked registry data. In all three countries, there was a clear upwards trend in cancer incidence with increasing platelet count for both sexes and at all age groups. Lung and colorectal were the most common sites. These results have important implications for the international application of this work; analysis of local health datasets will be crucial to determining appropriate thresholds. Appropriate upper thresholds will depend on local populations, healthcare needs, and priorities. Further research is needed to assess the likely impact of new recommendations on the healthcare system, on cancer outcomes, and patient benefit. Full article

The 1980 Ms 6.9 Irpinia earthquake was responsible for the activation or reactivation of numerous gravitative deformations mainly hosted by clayey lithotypes, affecting wide areas of Benevento Province and the Sele and Ofanto R. Valleys. The case of Calitri offers valuable insights into a methodological approach to studying mass movements affecting human settlements. Post-earthquake investigations in Calitri involved extensive geognostic boreholes and in situ surveys, providing substantial data for lithological characterization and landslide modeling. Additionally, over the past two decades, satellite-based techniques have supported the mapping and characterization of ground deformations in this area, improving our understanding of spatiotemporal evolution. Despite these efforts, a detailed subsurface comprehensionof the tectono-stratigraphy and geometriesof gravity-induced deformation remains incomplete. This study aims to enhance our knowledge of gravity-driven deformations affecting urban areas by using deep-penetrating GroundPenetrating Radar (GPR) surveys to identify landslide-related structures, rupture surfaces, and lithological characterization of the involved lithotypes. The integration of GPR surveys with classical morphotectonic analysis led to the delineation of the main subsurface discontinuities (stratigraphy, tectonics, and gravity-related), correlating them with available geognostic data. This approach provided non-invasive, detailed insights into subsurface features and stands out as one of the rare case studies in Italy that employed the GPR method for landslide investigations. Full article

Landslides play a significant role in the morpho-evolutional processes of slopes, affecting them globally under various geological conditions. Often unnoticed due to low velocities, they cause diffuse damage and loss of economic resources to the infrastructure or villages built on them. Recognizing and mapping mass movements is crucial for mitigating economic and social impacts. Conventional monitoring techniques prove challenging for large areas, necessitating resource-intensive ground-based networks. Leveraging abundant synthetic aperture radar (SAR) sensors, satellite techniques offer cost-effective solutions. Among the various methods based on SAR products for detecting landslides, multi-temporal differential interferometry SAR techniques (MTInSAR) stand out for their precise measurement capabilities and spatiotemporal evolution analysis. They have been widely used in several works in the last decades. Using information from the official Italian landslide database (IFFI), this study employs Sentinel-1 imagery and two new processing chains, E-PS and E-SBAS algorithms, to detect deformation areas on the slopes of Calitri, a small town in Southern Italy; these algorithms assess the cumulated displacements and their state of activity. Taking into account the non-linear trends of the scatterers, these innovative algorithms have helped to identify a dozen clusters of points that correspond well with IFFI polygons. Full article

The restrictive measures adopted worldwide against SARS-CoV-2 produced a drastic reduction in respiratory pathogens, including RSV, but a dramatic rebound was thereafter reported. In this multicenter retrospective observational study in 15 Pediatric Emergency Departments, all children <3 years old with RSV infection admitted between 1 September and 31 December 2021 were included and compared to those admitted in the same period of 2020 and 2019. The primary aim was to evaluate RSV epidemiology during and after the COVID-19 pandemic peak. The secondary aims were to evaluate the clinical features of children with RSV infection. Overall, 1015 children were enrolled: 100 in 2019, 3 in 2020 and 912 in 2021. In 2019, the peak was recorded in December, and in 2021, it was recorded in November. Comparing 2019 to 2021, in 2021 the median age was significantly higher and the age group 2–3 years was more affected. Admissions were significantly higher in 2021 than in 2020 and 2019, and the per-year hospitalization rate was lower in 2021 (84% vs. 93% in 2019), while the duration of admissions was similar. No difference was found in severity between 2019–2020–2021. In conclusion, after the COVID-19 pandemic, an increase in RSV cases in 2021 exceeding the median seasonal peak was detected, with the involvement of older children, while no difference was found in severity. Full article

The evaluation of cereal-based product contamination by pesticide residues is a topic of worldwide importance, and reliable analytical methods for official check analyses and monitoring studies are required for multi-residue analysis at trace levels. In this work, a validated multi-residual analytical method by gas-chromatography and tandem mass spectrometry coupled with a rapid QuEChERS procedure was used for the determination of 37 pesticides (pyrethroids, organophosphorus and organochlorine compounds) in 209 commercially available samples of cereals and 11 legumes, placed on the Italian market in 2018 and 2019, coming from different regions of Italy, eastern Europe, and some non-European countries. No pesticide traces were observed in the analyzed legume samples. A total of 18 cereal samples were found to be contaminated by at least one pesticide, with a concentration level higher than the corresponding quantification limit, but never exceeding the maximum level fixed in the European Regulations. This work is the first part of a surveillance study for pesticide control in food samples. Full article

This paper aims to present, through a photographic reportage, the current state of rebuilding of the most devastated villages by the earthquake that hit the Southern Italy on 23 November 1980, in Irpinia-Basilicata. The earthquake was characterized by magnitude Ml = 6.9 and epicentral intensity I₀ = X MCS. It was felt throughout Italy with the epicenter in the Southern Apennines, between the regions of Campania and Basilicata that were the most damaged areas. About 800 localities were serious damaged; 7,500 houses were completely destroyed and 27,500 seriously damaged. The photographic survey has been done in 23 towns during the last five years: Castelnuovo di Conza, Conza della Campania, Laviano, Lioni, Santomenna, Sant’Angelo dei Lombardi, Balvano, Caposele, Calabritto and the hamlet of Quaglietta, San Mango sul Calore, San Michele di Serino, Pescopagano, Guardia dei Lombardi, Torella dei Lombardi, Colliano, Romagnano al Monte, Salvitelle, Senerchia, Teora, Bisaccia, Calitri and Avellino. Forty years after the 1980 earthquake, the photographs show villages almost completely rebuilt with modern techniques where reinforced concrete prevails. Only in few instances, the reconstruction was carried out trying to recover the pre-existing building heritage, without changing the original urban planning, or modifying it. We argue that this photography collection allows to assess the real understanding of the geological information for urban planning after a major destructive seismic event. Even more than this, documenting the rebuilding process in a large epicentral area reveals the human legacy to the natural landscape, and our ability, or failure, to properly interpret the environmental fate of a site. Full article