Search Results (149)

Background: Concerns over women’s mental health have intensified globally, especially among mothers managing dual careers and family responsibilities. Positive Psychology Interventions (PPIs), such as gratitude journaling and well-being workshops, have demonstrated promise in enhancing mental health; however, their applicability in Arab contexts remains underexplored. This study aims to investigate the effectiveness of PPIs on mothers’ well-being, gratitude, depression, anxiety, and stress in Saudi Arabia. Methods: This quasi-experimental, one-group pretest–posttest study assessed the effects of a four-week PPI on 37 Saudi working mothers (aged 21–50 years) employed at a private school in Riyadh. The intervention included guided gratitude journaling thrice weekly and two workshops on positive psychology and gratitude. Pre- and post-intervention assessments used validated Arabic versions of the Depression Anxiety Stress Scale (DASS-21), WHO-5 Well-being Index, and Gratitude Questionnaire (GQ-6). Results: Significant improvements were found post-intervention: depression, anxiety, and stress scores decreased (p < 0.001), while well-being and gratitude increased (p = 0.001). However, participants with lower household income (<50,000 SAR) showed less improvement, indicating a potential moderating effect of socioeconomic status. Conclusions: The intervention demonstrated promising short-term improvements in mental health and well-being among Saudi mothers. The findings underscore the importance of culturally appropriate PPIs and highlight the need for further research using controlled, long-term designs. Limitations include the small, non-random sample, absence of a control group, and restriction to a single geographic region. Full article

This study investigates the impact of family engagement on student reading achievement in the United Arab Emirates (UAE) using counterfactual explainable artificial intelligence (CXAI) analysis. Drawing data from 24,600 students in the UAE PISA dataset, the analysis employed Gradient Boosting, SHAP (SHapley Additive exPlanations), and counterfactual simulations to model and interpret the influence of ten parental involvement variables. The results identified time spent talking with parents, frequency of family meals, and encouragement to achieve good marks as the strongest predictors of reading performance. Counterfactual analysis revealed that increasing the time spent talking with parents and frequency of family meals from their minimum (1) to maximum (5) levels, while holding other variables constant at their medians, could increase the predicted reading score from the baseline of 358.93 to as high as 448.68, marking an improvement of nearly 90 points. These findings emphasize the educational value of culturally compatible parental behaviors. The study also contributes to methodological advancement by integrating interpretable machine learning with prescriptive insights, demonstrating the potential of XAI for educational policy and intervention design. Implications for educators, policymakers, and families highlight the importance of promoting high-impact family practices to support literacy development. The approach offers a replicable model for leveraging AI to understand and enhance student learning outcomes across diverse contexts. Full article

Background: Syndromic inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders, involving the retina and additional organs. Over 80 forms of syndromic IRD have been described. Methods: We aimed to phenotypically and genotypically characterize a cohort of 171 individuals from 140 Israeli families with syndromic IRD. Ophthalmic examination included best corrected visual acuity, fundus examination, visual field testing, retinal imaging and electrophysiological evaluation. Most participants were also evaluated by specialists in fields relevant to their extra-retinal symptoms. Genetic analyses included haplotype analysis, homozygosity mapping, Sanger sequencing and next-generation sequencing. Results: In total, 51% of the families in the cohort were consanguineous. The largest ethnic group was Muslim Arabs. The most common phenotype was Usher syndrome (USH). The most common causative gene was USH2A. In 29% of the families, genetic analysis led to a revised or modified clinical diagnosis. This included confirmation of an atypical USH diagnosis for individuals with late-onset retinitis pigmentosa (RP) and/or hearing loss (HL); diagnosis of Heimler syndrome in individuals with biallelic pathogenic variants in PEX6 and an original diagnosis of USH or nonsyndromic RP; and diagnosis of a mild form of Leber congenital amaurosis with early-onset deafness (LCAEOD) in an individual with a heterozygous pathogenic variant in TUBB4B and an original diagnosis of USH. Novel genotype–phenotype correlations included biallelic pathogenic variants in KATNIP, previously associated with Joubert syndrome (JBTS), in an individual who presented with kidney disease and IRD, but no other features of JBTS. Conclusions: Syndromic IRDs are a highly heterogeneous group of disorders. The rarity of some of these syndromes on one hand, and the co-occurrence of several syndromic and nonsyndromic conditions in some individuals, on the other hand, complicates the diagnostic process. Genetic analysis is the ultimate way to obtain an accurate clinical diagnosis in these individuals. Full article

Background/Objectives: Social participation is important for healthy aging but challenging for older immigrants because of factors such as the loss of cultural community, language and transportation barriers, ageism, and racism. This study aimed to examine (1) the type of social activities in which older immigrants from Arabic (Arab), Mandarin (East Asian), and Punjabi-speaking (South Asian) communities in Canada engage; (2) their desire for more participation in social activities; and (3) factors they perceive as preventing their engagement in more social activities. Methods: Using a cross-sectional design, we collected data, using existing measures, from 476 older immigrants between fall 2022 and winter 2023. Descriptive statistics were used to analyze the data. Results: More than 75% of participants reported engagement in three solitary activities (having a hobby, going on a day trip; and using the internet and/or email) and more than 85% participated in community-based activities with family inside and outside and with friends outside the household. Most (71%) expressed a desire to participate in more social activities in the community, but they were prevented from doing so due to factors such as language barriers or not wanting to go alone. Conclusions: Interventions are needed to facilitate community-based participation among older immigrants and improve their quality of life. Full article

Parents provide most of the support needed for children with cerebral palsy (CP) to increase the child’s participation and independence. Understanding the experiences of parents caring for children with CP is essential for developing effective family programs and services. The current knowledge about parents’ experiences in CP is based on studies in Western countries, with little known about this phenomenon in Arab countries like Saudi Arabia. This study aimed to understand the unique experiences and support needs of Saudi parents caring for children with CP from a social-ecological perspective. We conducted a qualitative, exploratory, descriptive study involving 12 semi-structured interviews with mothers and fathers of children with different types of CP. We analyzed the data using a reflexive thematic approach, following six distinct phases. Participants’ narratives revealed a complex caregiving journey marked by both challenges and rewards. Support from Saudi nuclear and extended family members was considered important; however, many parents expressed a need for additional physical and financial assistance from their families. Parents reported feeling stressed and experiencing challenges in accessing and navigating educational and healthcare services. Our findings highlight that Islamic values play a crucial role in the experiences of Saudi parents. These values foster a sense of collectivism, highlighting the importance of family support and community involvement, which can affect the Saudi caregiving environment. Parents remain an essential yet often invisible part of the Saudi caregiving system. Without adequate support, parents are at risk of experiencing social, financial, academic, physical, and mental health challenges, which may affect their overall family well-being. Future work may need to consider spiritual and gender roles when developing programs or services to support Saudi parents of children with CP. Full article

Background: Premature hair graying (PHG) is one of the most prevalent conditions affecting individuals worldwide. It has been recognized as an important cause of low self-esteem, with a significant physical and social impact. This study investigated the factors associated with PHG by comparing medical students and resident physicians to other non-medical majors at Imam Abdulrahman Bin Faisal University (IAU). Methods: This is a comparative cross-sectional study conducted on resident physicians and students from 10 different colleges of IAU, Eastern Province, Saudi Arabia. This study evaluated the characteristics of PHG and its associated risk factors using an online distributed questionnaire. Results: A total of 2644 students and resident physicians were included in this study, with 45.6% coming from medical colleges. The findings show that the premature graying of hair was higher among obese and overweight individuals and those with a combined deficiency of vitamins B12 and vitamin D. Other factors associated with PHG included a family history of PHG, a lack of exercise, smoking, and allergic rhinitis. Gray hair onset before 25 years old was higher among those with high stress levels (95%) than those with moderate (90%) and or mild (86%) stress levels (p = 0.029). Conclusions: In our study, higher stress levels were related to an earlier age of PHG onset, and there was no difference between medical and non-medical students in PHG. Recommendations for future research include randomized clinical trials and larger cohort studies regarding the characteristics of PHG in the Middle East and those with Arabic ethnicity and assessing the medications that induce possible hair repigmentation. Full article

This study investigates the impact of family socio-economic status on children’s bilingual oral language and reading abilities. The participants were 92 Arabic–English bilingual children (Mean_age = 8.52 years old) in Grade 3 of primary schools and their parents in the United Arab Emirates. A correlational research design was used. The children completed several bilingual oral language and reading tests, and their parents filled in the family background questionnaire. The results of general regression show that mothers’ education level and family income affected children’s English, but not Arabic, oral language and word reading abilities. Family income was a significant predictor of children’s English oral language skills, and mothers’ education level contributed to children’s English word reading. However, fathers’ education level did not predict children’s bilingual abilities. The contextual influence on children’s language and literacy development is discussed. Full article

Background: Gamma-glutamylcysteine synthetase catalyzes the first and rate-limiting step in the synthesis of glutathione. Gamma-glutamylcysteine synthetase deficiency is a very rare condition that has so far been detected so far in nine patients from seven families worldwide. The inheritance of this disorder is autosomal recessive. Methods: We report a case of 4.11-year-old boy, of Arab-Muslim origin, living in an Arab town in Israel who presented at the age of 2 days with severe anemia, reticulocytosis, and leukocytosis. Investigation for common causes of hemolytic anemia was negative (peripheral blood smear was normal, and he had a negative Coombs test, normal G6PD, and normal flow cytometry spherocytosis). The anemia worsened during the following days (hemoglobin (Hb): 7.2 g/dL) and he needed several blood transfusions. NGS (next-generation sequencing) gene panel analysis was performed. Results: In an NGS gene panel analysis for hereditary hemolytic anemias, we found a homozygotic change in the GCLC gene—G53.385.643c379C > T(homo)pArg127Cys—which confirms the diagnosis of gamma-glutamylcysteine synthetase deficiency. An additional rare change was found in this case in the GCLC gene, with unknown clinical significance: g.53373917, c 828 + 3A > G. Except for chronic anemia (Hb levels around 8 g/dL), the child has normal physical and neurological development. Conclusions: This study reports a rare case of gamma-glutamylcysteine synthetase deficiency in a 4.11-year-old Arab-Muslim boy from Israel who presented with severe anemia at 2 days old, aiming to document the first such case in the Middle East and contribute to the medical literature on this extremely rare condition that has only been detected in nine patients worldwide. Genetic analysis revealed a homozygotic change in the GCLC gene, confirming the diagnosis, and while the patient experiences chronic anemia, he maintains normal physical and neurological development, adding valuable insights to the understanding of this rare genetic disorder. An additional rare change was found in this case in the GCLC gene, with unknown clinical significance: g.53373917, c 828 + 3A > G. Full article

This study investigates social support type and long-term mortality following AMI. Demographic and clinical data were collected retrospectively from a tertiary hospital for all patients with AMI (2011–2017). Study groups based on support type were defined: (1) employed partner (served as the reference group); (2) unemployed partner; (3) no partner, family support; (4) institutional or benefit-dependent; and (5) non-kin support (caregiver). Ten-year all-cause mortality risk was assessed and compared between the groups. We identified 2652 AMI patients with recorded support type: mean age 67.6 (SD = 14) years, 66% male; 40% had no partner, followed by those with an unemployed partner (31%). Over the follow-up of (median) 7.6 years, 1471 patients died; significantly higher mortality rates were observed in patients without family support (67.9%) or receiving non-kin support (94.9%). Those with non-kin support were at the highest mortality risk, AdjHR = 2.20, 95% CI: 1.67–2.91, p < 0.001, as compared with the reference group. Subgroup analyses found women below age 75 years, Arab women, and those with higher functional status to be most vulnerable to mortality in the absence of family support. Lack of family support was associated with increased long-term mortality among AMI patients. Assessment of support status among AMI patients is integral for secondary prevention. Full article

Pregnancy and transition to motherhood are significant experiences accompanied by manifold changes, particularly during times of crisis, such as exposure to traumatic events, which involve further levels of complexity and vulnerability. This is especially true for Arab women in Israel, considering the interactions between their physical, mental, and social environments, and their impact on health during pregnancy and childcare in wartime. This study sought to examine the experience of Arab women in Israel, who experienced intersectional marginalization as women in a traditional patriarchal society who belong to a minority group, during the perinatal period, following the events of 7 October 2023, and the subsequent Israel–Hamas war. Semi-structured in-depth interviews were conducted with ten participants in different stages of pregnancy and young mothers to infants up to a year old. The thematic analysis revealed four main themes: The impact of the war on intrapersonal identity; The impact within the couple’s relationship identity; The impact on family identity; Socio-political identity. Shining a spotlight on the experiences of Arab women in Israel and their daily functioning in the current complex reality reveals unique challenges, encompassing profound feelings of fear, anxiety, and imposed silence. Deepening the understanding of marginalized women’s experiences can help policymakers in the field of women’s health to design tailored adaptations in health policies for Arab women from minority groups, navigating the complexities of transitioning to motherhood during periods of social instability and wartime challenges. Full article

Background: Exclusive breastfeeding (EB), feeding an infant solely breast milk, has been recommended worldwide due to its health benefits for infants and mothers. However, EB rates remain low, due to several socio-demographic, occupational, and cultural factors. Objectives: Our aim was to investigate the factors associated with EB amongst Arab mothers living in Israel, i.e., age, education, religiosity, employment status, and the number of children which impact breastfeeding practices. Methods: Data were collected through surveys from Arab mothers of different religious and geographical backgrounds. Results: The findings revealed that older maternal age, higher levels of religiosity, and an increased number of children were positively associated with EB. Employment reduced EB. Muslim mothers were more likely to combine breastfeeding with formula; Christian and Druze mothers showed higher EB rates. Geographical disparities were also noted. Conclusions: This study highlights the complex interplay of socio-demographic and cultural factors that impact breastfeeding practices amongst Arab mothers in Israel, with significant implications for policy development and maternal support programs. We underscore the importance of incorporating religious and cultural considerations into breastfeeding promotion strategies. Public health initiatives should target support for working mothers by advocating extended maternity leave and breastfeeding-friendly workplace policies. Furthermore, community-based interventions should engage family members in supporting breastfeeding mothers. Full article

Family relationships are important for the well-being of older adults, yet these relationships may involve ambivalence and/or conflict, particularly in high-stress scenarios such as hospitalization. This study aimed to identify factors predicting conflict between hospitalized older adults and family members, considering individual, social, and cultural factors. The sample comprised 573 cognitively intact older adults (65+) admitted to internal units in Israeli hospitals. Structural equation modeling (SEM) revealed that emotional support a decrease in conflict (β = −0.105, p = 0.007), while instrumental care (β = 0.146, p = 0.003), number of visitors (β = 0.125, p = 0.011), and the spouse being a primary caregiver (β = 0.159, p < 0.001) was associated with an increase in conflict. On the cultural level, being a Former Soviet Union (FSU) immigrant was a risk factor (β = 0.106, p = 0.016), while being an Israeli Arab had an indirect effect mediated by involvement in instrumental care and larger visitor numbers, which increased the risk for conflict (β = 0.087, p = 0.045). On the individual level, depressive symptoms increased conflict via emotional support (β = 0.01, p = 0.031), and independence in activities of daily living reduced conflict via lower instrumental care (β = −0.002, p = 0.003). These findings highlight the complex interplay of risk and protective factors in predicting conflict and highlight the role of social and cultural factors. Targeted interventions for spouses, caregivers providing instrumental support, and FSU immigrants may help reduce conflict during hospitalization. Full article

Women entrepreneurs in the Middle Eastern region, particularly in the United Arab Emirates (UAE), face several challenges (e.g., cultural) coupled with the recent transformation of the digital economy. This issue poses a significant challenge for financing the business operations. Thus, this study aims to find the relationship between prior family business exposure, growth intention, motivation, and financial bootstrapping with the mediating role of prior experiences among women entrepreneurs in the UAE. A quantitative survey questionnaire method was used to collect responses from 318 women business owners in different regions of the UAE. The findings of the study suggest that there is a positive relationship between prior family business exposure and financial bootstrapping and growth intention and financial bootstrapping, and prior experience plays a mediating role among all exogenous variables. The study offers a unique perspective on the intersection between prior family business exposure, growth intention, motivation, and financial bootstrapping, highlighting the mediating role of prior experience in a demographical and geographic context (e.g., UAE) that is under-researched regarding financial strategies. Full article

Background/Objectives: Oligopolyposis is a rare condition characterized by 10 to 100 adenomas in the colon. We aimed to investigate the clinical and endoscopic features of patients with oligopolyposis by comparing patients who carried pathogenic mutations and those who did not. Methods: This retrospective study included patients with a cumulative count of 10–100 adenomas found in the colon, at a single center. Clinical, endoscopic, and genetic data were analyzed. Results: A total of 155 patients were identified as having oligopolyposis. Genetic testing using a multigene panel was performed among 85 (55%) patients, while founder or family mutation testing was performed among 7 (4.5%) patients. No genetic testing was carried out in 63 (40.5%) patients. Pathogenic polyposis-related mutations were identified in 14 (16%) out of 85 patients who underwent genetic testing. Among these, seven (50%) mutations were found in the APC gene and seven (50%) in the MUTYH gene. A significantly higher proportion of mutation carriers were of Arab ethnicity (35.7% vs. 4.2%, p < 0.001). There was no significant difference between carriers and non-carriers with regard to family history of polyps or cancer. Colorectal cancer was found to be the initial presentation in three (21%) carriers and five (7%) non-carriers. Colonic surgeries were reported among 4 (28.6%) carriers and 13 (18.6%) non-carriers. No significant differences in the rates of colorectal cancer or death were observed between carriers and non-carriers. Conclusions: Only a small proportion of patients with oligopolyposis were found to be mutation carriers, with significant ethnic differences in mutation frequency but no notable differences in clinical features, colorectal cancer rates, or mortality. Full article

This paper reports on the affordances and constraints encountered in the case of an innovative project designed to support early literacy development in Arabic and English while enhancing father-child wellbeing in Abu Dhabi. The project sought to encourage Emirati fathers to engage in interactive shared book reading at home with their young children. In a context where adult–child home reading is not a traditional practice and where children’s reading proficiency in public schools is often below international standards, the project sought to support families with their children’s early literacy development and to develop positive dispositions towards reading. Fathers (N = 80) of kindergarten children (4–5 years) in state schools in the United Arab Emirates (UAE) were invited to participate in interactive workshops about shared parent–child reading. Fathers were provided with selected, high-quality books in both Arabic and English to read aloud with their children at home and were given guidance on ways to read interactively. In this paper, which draws upon survey results, focus group recordings, and researcher field notes from the workshop sites, the affordances and constraints encountered in supporting early home reading and parent–child wellbeing are explored. Recommendations are made for similar reading and wellbeing programs in multilingual contexts. These include providing accessible information to both fathers and mothers on the importance of reading with their children at home, sharing tips and modelling parent–child interactive reading, and the provision of culturally and linguistically appropriate books for families. Full article