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124,953 Results Found

  • Article
  • Open Access
10 Citations
7,093 Views
14 Pages

Cyano-B12 or Whey Powder with Endogenous Hydroxo-B12 for Supplementation in B12 Deficient Lactovegetarians

  • Sadanand Naik,
  • Namita Mahalle,
  • Eva Greibe,
  • Marie S. Ostenfeld,
  • Christian W. Heegaard,
  • Ebba Nexo and
  • Sergey N. Fedosov

6 October 2019

Lactovegetarians (n = 35) with low vitamin B12 (B12) status were intervened for eight weeks capsules containing cyano-B12 (CN-B12), (2 × 2.8 µg/day), or equivalent doses of endogenous B12 (mainly hydroxo-B12 (HO-B12)) in whey powder. Bloo...

  • Article
  • Open Access
56 Citations
8,925 Views
18 Pages

Anti-Tumor Effects of Vitamin B2, B6 and B9 in Promonocytic Lymphoma Cells

  • Kathleen Mikkelsen,
  • Monica D. Prakash,
  • Nyanbol Kuol,
  • Kulmira Nurgali,
  • Lily Stojanovska and
  • Vasso Apostolopoulos

Chronic inflammation can lead to tumour initiation and progression. Vitamin B complex has the ability to regulate the immune response and, therefore, inflammation but many of the mechanistic and molecular processes involved in this regulation are sti...

  • Review
  • Open Access
20 Citations
6,813 Views
23 Pages

Most B cell lymphomas arise from the oncogenic transformation of B cells that have undergone the germinal center (GC) reaction of the T cell-dependent immune response, where high-affinity memory B cells and plasma cells are generated. The high prolif...

  • Article
  • Open Access
9 Citations
2,227 Views
29 Pages

8 December 2023

Boron presents an important role in chemistry, biology, and materials science. Diatomic transition-metal borides (MBs) are the building blocks of many complexes and materials, and they present unique electronic structures with interesting and peculia...

  • Article
  • Open Access
5 Citations
2,738 Views
20 Pages

18 January 2023

The BeiDou Global Navigation Satellite System (BDS), including the second generation (BDS-2) and the third generation (BDS-3), has been widely used in areas of positioning, navigation, and timing (PNT). One of the essential prerequisites for accurate...

  • Article
  • Open Access
3,030 Views
12 Pages

Vitamin B1, B2, and B6 Intakes and Risk of Gastric Cancer: Findings from a Case-Control Study

  • Ngoan Tran Le,
  • Yen T.-H. Pham,
  • Huy Thanh Dang,
  • Linh Thuy Le,
  • Nhi Y.-N. Huynh,
  • Jennifer Cullen and
  • Hung N. Luu

18 December 2024

Background/Objectives: Gastric cancer is one of the leading malignancies worldwide. B vitamins play important roles in DNA synthesis and methylation because they are considered co-enzymes in one-carbon metabolism. There is inconclusive evidence regar...

  • Article
  • Open Access
17 Citations
3,976 Views
14 Pages

AKR1B1 and AKR1B10 as Prognostic Biomarkers of Endometrioid Endometrial Carcinomas

  • Marko Hojnik,
  • Snježana Frković Grazio,
  • Ivan Verdenik and
  • Tea Lanišnik Rižner

7 July 2021

The roles of aldo-keto reductase family 1 member B1 (AKR1B1) and B10 (AKR1B10) in the pathogenesis of many cancers have been widely reported but only briefly studied in endometrial cancer. To clarify the potential of AKR1B1 and AKR1B10 as tissue biom...

  • Review
  • Open Access
54 Citations
12,597 Views
23 Pages

B-cell receptor (BCR) is a B cell hallmark surface complex regulating multiple cellular processes in normal as well as malignant B cells. Igα (CD79a)/Igβ (CD79b) are essential components of BCR that are indispensable for its functionality,...

  • Article
  • Open Access
8 Citations
3,331 Views
23 Pages

17 November 2022

The BeiDou Global Navigation Satellite System (BDS-3) can provide PPP-B2b satellite-based Precise Point Positioning (PPP) real-time service to the Asia–Pacific region via PPP-B2b signal transmitted from the three Geostationary Earth Orbit (GEO)...

  • Article
  • Open Access
4 Citations
4,358 Views
16 Pages

Optimization of Vitamin B1, B2, and B6 Absorption in Nang Tay Dum Floating Rice Grains

  • Thi Thao Loan Nguyen,
  • Thi Mong Nghi Pham,
  • Thanh Binh Ho and
  • Binh Ly-Nguyen

23 August 2024

As reported by the FAO, in 2022, approximately 735 million people experienced undernourishment, underscoring the critical need for effective strategies to address micronutrient deficiencies. Among these strategies, the mass fortification of staple fo...

  • Article
  • Open Access
723 Views
24 Pages

Application of Pure and Ion-Doped FeB, CoB, MnB, and Fe2B Nanoparticles for Magnetic Hyperthermia

  • Angel T. Apostolov,
  • Iliana N. Apostolova and
  • Julia M. Wesselinowa

12 June 2025

This study investigates Mn1−xXxB (X = Fe, Co) and (Fe1−xCox)2B nanoparticles as candidates for self-controlled magnetic hyperthermia (SCMH) in cancer therapy. Using a microscopic model and Green’s function techniques, we calculate t...

  • Article
  • Open Access
12 Citations
8,023 Views
14 Pages

PAGE-B and REACH-B Predicts the Risk of Developing Hepatocellular Carcinoma in Chronic Hepatitis B Patients from Northeast, Brazil

  • Alessandra Porto de Macedo Costa,
  • Marcos Antonio Custódio Neto da Silva,
  • Rogério Soares Castro,
  • Ana Leatrice de Oliveira Sampaio,
  • Antônio Machado Alencar Júnior,
  • Márcia Costa da Silva and
  • Adalgisa de Souza Paiva Ferreira

31 March 2022

This study aims to evaluate the accuracy of the PAGE-B and REACH-B scores in predicting the risk of developing HCC in patients with chronic hepatitis B regularly followed up at a reference service in the State of Maranhão. A historical, longit...

  • Article
  • Open Access
2 Citations
1,564 Views
21 Pages

11 February 2025

In 2020, BDS-3 began broadcasting high-precision positioning correction products through B2b signals, effectively addressing the limitations of ground-based augmentation. However, challenges such as the “south wall effect” from geostation...

  • Review
  • Open Access
82 Citations
12,768 Views
33 Pages

7 February 2014

Human small heat shock proteins are molecular chaperones that regulate fundamental cellular processes in normal unstressed cells as well as in many cancer cells where they are over-expressed. These proteins are characterized by cell physiology depend...

  • Article
  • Open Access
2 Citations
2,619 Views
14 Pages

Due to alternative splicing, the SLCO1B3 gene encodes two protein variants; the hepatic uptake transporter liver-type OATP1B3 (Lt-OATP1B3) and the cancer-type OATP1B3 (Ct-OATP1B3) expressed in several cancerous tissues. There is limited information a...

  • Article
  • Open Access
31 Citations
6,526 Views
19 Pages

31 October 2018

The purpose of this study is to explore the driving forces of innovation in micro and small enterprises (MSEs) in the tourism industry and to understand how these drivers help allocate and utilize resources, thereby increasing innovations’ succ...

  • Article
  • Open Access
9 Citations
3,468 Views
20 Pages

Background: Gram-negative infections of the peritoneal cavity result in profound modifications of peritoneal B cell populations and induce the migration of peritoneal B cells to distant secondary lymphoid organs. However, mechanisms controlling the e...

  • Article
  • Open Access
35 Citations
6,669 Views
16 Pages

22 July 2019

The sharing economy is treated as an alternative consumption model. Its aim is to increase the efficiency of the resources used and create a new value for society. In order to create a new value for business, attempts are being made to implement a sh...

  • Review
  • Open Access
25 Citations
13,365 Views
29 Pages

Simplifying the B Complex: How Vitamins B6 and B9 Modulate One Carbon Metabolism in Cancer and Beyond

  • Carolina N. Franco,
  • Laurence J. Seabrook,
  • Steven T. Nguyen,
  • Jack T. Leonard and
  • Lauren V. Albrecht

11 October 2022

Vitamin B micronutrients are essential regulators of one carbon metabolism that ensures human health. Vitamin B9, or folate, lies at the heart of the folate cycle and converges with the methionine cycle to complete the one carbon pathway. Additionall...

  • Article
  • Open Access
11 Citations
4,546 Views
21 Pages

20 February 2024

This study empirically examines factors that can influence the sustainable corporate performance of Korean business-to-business (B2B) companies with the help of unique survey data. Factors such as technological capability, the chief executive officer...

  • Article
  • Open Access
15 Citations
4,397 Views
21 Pages

Analysis of BDS-3 PPP-B2b Positioning and Time Transfer Service

  • Runzhi Zhang,
  • Zaimin He,
  • Langming Ma,
  • Gongwei Xiao,
  • Wei Guang,
  • Yulong Ge,
  • Xiangbo Zhang,
  • Jihai Zhang,
  • Jian Tang and
  • Xueqing Li

9 June 2022

With the completion of the BeiDou global navigation satellite system (BDS-3), the BeiDou Navigation Satellite System Signal In Space Interface Control Document Precise Point Positioning Service Signal PPP-B2b (Version 1.0) was officially announced, a...

  • Article
  • Open Access
3 Citations
4,812 Views
23 Pages

A Study on the Performance of B&B Operations Is Conducted in Sustainable Tourism

  • Chien-Tai Hsu,
  • Yi-Chun Lin,
  • Kai-Chao Yao and
  • Pei-Chi Ma

20 September 2024

Taiwan’s bed and breakfast (B&B) industry has experienced significant development in its nearly 25-year history, transforming from B&B run by retirees to mature service providers that adopt modern business and Internet technology skills...

  • Review
  • Open Access
9 Citations
4,713 Views
16 Pages

22 June 2023

Understanding the molecular mechanisms of neurological disorders is necessary for the development of personalized medicine. When the diagnosis considers not only the disease symptoms, but also their molecular basis, treatments tailored to individual...

  • Article
  • Open Access
44 Citations
5,963 Views
28 Pages

28 January 2022

BeiDou Global Navigation Satellite System (BDS-3) provides a regional Precise Point Positioning (PPP) service, called PPP-B2b, for users in China and surrounding areas through B2b signal transmitted from its three geostationary earth orbit (GEO) sate...

  • Article
  • Open Access
32 Citations
5,695 Views
17 Pages

Ni–B alloys deposited by the electroless method are considered to be hard variants of the electroless nickel family. Inclusion of Mo or W to form ternary alloys improves the thermal stability of electroless nickel coatings. Therefore, in the pr...

  • Article
  • Open Access
25 Citations
5,781 Views
23 Pages

An In-Depth Assessment of the New BDS-3 B1C and B2a Signals

  • Qinghua Zhang,
  • Yongxing Zhu and
  • Zhengsheng Chen

21 February 2021

An in-depth and comprehensive assessment of new observations from BDS-3 satellites is presented, with the main focus on the Carrier-to-Noise density ratio (C/N0), the quality of code and carrier phase observations for B1C and B2a signal. The signal c...

  • Review
  • Open Access
18 Citations
6,513 Views
17 Pages

EphrinB2–EphB4 Signaling in Neurooncological Disease

  • Andras Piffko,
  • Christian Uhl,
  • Peter Vajkoczy,
  • Marcus Czabanka and
  • Thomas Broggini

31 January 2022

EphrinB2–EphB4 signaling is critical during embryogenesis for cardiovascular formation and neuronal guidance. Intriguingly, critical expression patterns have been discovered in cancer pathologies over the last two decades. Multiple connections...

  • Article
  • Open Access
13 Citations
3,036 Views
16 Pages

Performance Assessment of BDS-3 PPP-B2b/INS Loosely Coupled Integration

  • Xiaofei Xu,
  • Zhixi Nie,
  • Zhenjie Wang,
  • Boyang Wang and
  • Qinghuai Du

21 June 2022

The BeiDou global navigation satellite system (BDS-3) has been officially providing a real-time precise point positioning (PPP) augmentation service, known as the PPP-B2b service, since 2020. Decimeter-level positioning accuracy is expected to be ach...

  • Article
  • Open Access
19 Citations
6,439 Views
21 Pages

Functional Characterization of Tomato Phytochrome A and B1B2 Mutants in Response to Heat Stress

  • Islam M. Y. Abdellatif,
  • Shaoze Yuan,
  • Renhu Na,
  • Shizue Yoshihara,
  • Haruyasu Hamada,
  • Takuya Suzaki,
  • Hiroshi Ezura and
  • Kenji Miura

31 January 2022

Heat stress (HS) is a prevalent negative factor affecting plant growth and development, as it is predominant worldwide and threatens agriculture on a large scale. PHYTOCHROMES (PHYs) are photoreceptors that control plant growth and development, and t...

  • Article
  • Open Access
10 Citations
3,177 Views
11 Pages

Effects of TiB2 Particles on the Microstructure Evolution and Mechanical Properties of B4C/TiB2 Ceramic Composite

  • Haiyan Niu,
  • Yu Zhu,
  • Ning You,
  • Yangwei Wang,
  • Huanwu Cheng,
  • Dujun Luo,
  • Mengying Tang and
  • Jiamin Zhang

11 September 2021

B4C/TiB2 ceramic composites reinforced with three size scales (average particle size: 7 μm, 500 nm, and 50 nm) of TiB2 were prepared by using a pressureless sintering furnace at 2100 °C under Ar atmosphere for 60 min. The results demonstrated that du...

  • Article
  • Open Access
2 Citations
4,428 Views
28 Pages

Optimal Implementations of 8b/10b Encoders and Decoders for AMD FPGAs

  • Stefan Popa,
  • Mihai Ivanovici and
  • Radu-Mihai Coliban

The 8b/10b IBM encoding scheme is used in a plethora of communication technologies, including USB, Gigabit Ethernet, and Serial ATA. We propose two primitive-based structural designs of an 8b/10b encoder and two of an 8b/10b decoder, all targeted at...

  • Review
  • Open Access
42 Citations
14,894 Views
11 Pages

4 May 2016

The family of NF-κB transcription factors plays a key role in diverse biological processes, such as inflammatory and immune responses, cell survival and tumor development. Beyond the classical NF-κB activation pathway, a second NF-κB pathway has more...

  • Article
  • Open Access
57 Citations
11,011 Views
17 Pages

Dietary Sources of Vitamin B-12 and Their Association with Vitamin B-12 Status Markers in Healthy Older Adults in the B-PROOF Study

  • Elske M. Brouwer-Brolsma,
  • Rosalie A. M. Dhonukshe-Rutten,
  • Janneke P. Van Wijngaarden,
  • Nikita L. van der Zwaluw,
  • Nathalie Van der Velde and
  • Lisette C. P. G. M. De Groot

14 September 2015

Low vitamin B-12 concentrations are frequently observed among older adults. Malabsorption is hypothesized to be an important cause of vitamin B-12 inadequacy, but serum vitamin B-12 may also be differently affected by vitamin B-12 intake depending on...

  • Article
  • Open Access
9 Citations
6,536 Views
13 Pages

Comparative Bioavailability of Synthetic B12 and Dietary Vitamin B12 Present in Cow and Buffalo Milk: A Prospective Study in Lactovegetarian Indians

  • Namita Mahalle,
  • Vijayshri Bhide,
  • Eva Greibe,
  • Christian W. Heegaard,
  • Ebba Nexo,
  • Sergey N. Fedosov and
  • Sadanand Naik

1 February 2019

We assessed improvements in the vitamin B12 status of Indian lactovegetarians receiving four weeks supplementation with natural B12 in milk versus cyano-B12 in capsules. Three groups (n = 22, 23, 22) received daily oral doses of cyano-B12 (2 ×...

  • Review
  • Open Access
74 Citations
17,581 Views
30 Pages

20 October 2018

The cellular kinases inhibitory-κB kinase (IKK) α and Nuclear Factor-κB (NF-κB)-inducing kinase (NIK) are well recognised as key central regulators and drivers of the non-canonical NF-κB cascade and as such dictate the i...

  • Article
  • Open Access
4 Citations
4,201 Views
14 Pages

11 March 2021

Committed Business-to-Business (B2B) relationships are linked to sustainable business partnerships and greater profitability. As competition increases, suppliers must seek to differentiate by shifting the focus of their offerings from the product to...

  • Article
  • Open Access
17 Citations
12,757 Views
11 Pages

Synthesis and Reactions of Furo[2,3-b]pyrroles

  • A. Krutosiková,
  • C. A. Ramsden,
  • M. Dandárová and
  • A. Lycka

20 April 1997

Methyl 6H-furo[2,3-b]pyrrole-5-carboxylate (2a) was prepared by thermolysis of the corresponding methyl 2-azido-3-(3-furyl)propenoate (1). 6-Methyl (2b) and 6-benzyl (2c) derivatives were obtained using phase-transfer catalysis conditions (PTC). The...

  • Article
  • Open Access
11 Citations
4,424 Views
20 Pages

Stimulation of Tomato Drought Tolerance by PHYTOCHROME A and B1B2 Mutations

  • Islam M. Y. Abdellatif,
  • Shaoze Yuan,
  • Shizue Yoshihara,
  • Takuya Suzaki,
  • Hiroshi Ezura and
  • Kenji Miura

13 January 2023

Drought stress is a severe environmental issue that threatens agriculture at a large scale. PHYTOCHROMES (PHYs) are important photoreceptors in plants that control plant growth and development and are involved in plant stress response. The aim of thi...

  • Article
  • Open Access
3 Citations
2,075 Views
22 Pages

Sub-Nanosecond UTC Dissemination Based on BDS-3 PPP-B2b Service

  • Zhe Zhang,
  • Baoqi Sun,
  • Kan Wang,
  • Xiaohong Han,
  • Haiyan Yang,
  • Ge Wang,
  • Meifang Wu,
  • Yuanxin Wang,
  • Changjiang Geng and
  • Xuhai Yang

21 December 2023

The BeiDou-3 system (BDS-3) broadcasts PPP-B2b signals to provide real-time PPP service. Compared with the traditional PPP technique, the PPP-B2b service broadcasts corrections through satellite links, covers a wide area, and is independent of the in...

  • Systematic Review
  • Open Access
1 Citations
7,230 Views
13 Pages

Co-Creation with AI in B2B Markets: A Systematic Literature Review

  • David Fehrenbach,
  • Carolina Herrando and
  • María José Martín-De Hoyos

13 September 2024

Artificial intelligence (AI) has significantly disrupted B2B markets, impacting companies at the product, service, and organizational levels. A key focus is on how to leverage the power of AI to augment and automate activities to create value for cus...

  • Article
  • Open Access
7 Citations
3,374 Views
23 Pages

Assessing Trans-Inhibition of OATP1B1 and OATP1B3 by Calcineurin and/or PPIase Inhibitors and Global Identification of OATP1B1/3-Associated Proteins

  • John T. Powell,
  • Ruhul Kayesh,
  • Alexandra Ballesteros-Perez,
  • Khondoker Alam,
  • Pascaline Niyonshuti,
  • Erik J. Soderblom,
  • Kai Ding,
  • Chao Xu and
  • Wei Yue

Organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 are key determinants of drug–drug interactions (DDIs). Various drugs including the calcineurin inhibitor (CNI) cyclosporine A (CsA) exert preincubation-induced trans-inhibitory effec...

  • Article
  • Open Access
8 Citations
6,198 Views
14 Pages

27 November 2020

Temporal dynamics in business-to-business (B2B) relationships are the evolution of B2B relationship stages. This study offers new insights in examining the impact of the temporal dynamics on firm performance during the B2B relationship stages. Drawin...

  • Article
  • Open Access
1 Citations
660 Views
21 Pages

Enhancing PPP-B2b Performance with Regional Atmospheric Augmentation

  • Qing Zhao,
  • Shuguo Pan,
  • Wang Gao,
  • Xianlu Tao,
  • Hao Liu,
  • Zeyu Zhang and
  • Qiang Wang

23 October 2025

Currently, the PPP-B2b service faces challenges such as long convergence times and re-convergence issues after signal interruptions due to the lack of high-precision atmospheric enhancement. To address this, this study develops a multi-frequency unco...

  • Short Note
  • Open Access
1 Citations
2,097 Views
5 Pages

2-((4-(2-Ethylhexyl)-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indol-7-yl)methylene)malononitrile

  • Nikita S. Gudim,
  • Ekaterina A. Knyazeva,
  • Konstantin P. Trainov and
  • Oleg A. Rakitin

11 November 2022

New small acceptor–donor (A–D) molecules have been recently investigated as a component of organic solar cells. In this research, 2-((4-(2-ethylhexyl)-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indol-7-yl)methylene)malononitrile was prepared fro...

  • Article
  • Open Access
3 Citations
3,462 Views
9 Pages

12 October 2018

Foods contain natural vitamin B12 forms, such as hydroxo–B12 (HO–B12), whereas vitamin pills contain the synthetic cyano–B12 (CN–B12). Recent studies in rats showed different tissue distributions of CN–B12 and HO–B...

  • Article
  • Open Access
34 Citations
8,610 Views
13 Pages

11 August 2018

To assess the association between intake of folate, vitamin B6, and vitamin B12 with hyperuricemia (HU) among adults from the United States (US), we extracted relevant data from 24,975 US adults aged 20–85 years from the National Health and Nutrition...

  • Article
  • Open Access
8 Citations
3,479 Views
14 Pages

24 August 2022

Elucidation of the factors responsible for hepatitis B virus (HBV) is extremely important in order to understand the viral life cycle and pathogenesis, and thereby explore potential anti-HBV drugs. The recent determination that sodium taurocholate co...

  • Article
  • Open Access
2,269 Views
17 Pages

Method for B Cell Receptor Enrichment in Malignant B Cells

  • Puja Bhattacharyya,
  • Richard I. Christopherson,
  • Kristen K. Skarratt and
  • Stephen J. Fuller

26 June 2024

B cells are central to the adaptive immune response and provide long-lasting immunity after infection. B cell activation is mediated by the surface membrane-bound B cell receptor (BCR) following recognition of a specific antigen. The BCR has been cha...

  • Article
  • Open Access
5 Citations
3,507 Views
18 Pages

Real-Time Precise Point Positioning during Outages of the PPP-B2b Service

  • Yufei Chen,
  • Xiaoming Wang,
  • Kai Zhou,
  • Jinglei Zhang,
  • Cong Qiu,
  • Haobo Li and
  • Shiji Xin

30 January 2023

The precise point positioning service on B2b signal (PPP-B2b) is a real-time decimeter-level positioning service provided by the BeiDou-3 Global Navigation Satellite System (BDS-3). The service provides users with high-precision orbit and clock corre...

  • Article
  • Open Access
10 Citations
2,167 Views
10 Pages

12 December 2022

To analyze the high-temperature oxidation behavior of TiB2-HfB2-Ni cermet material, TiB2-HfB2-Ni cermets were fabricated by hot-pressing sintering technology. The oxidation resistance and the thermal fracture of TiB2-HfB2-Ni cermet were investigated...

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