Nucleocytoviricota
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".
Deadline for manuscript submissions: 1 March 2026 | Viewed by 718
Special Issue Editor
Interests: comparative and evolutionary genomics; dsDNA viruses; discovery and characterization of novel viruses; understanding microbial diversity and viral evolution
Special Issue Information
Dear Colleagues,
In recent years, research on giant viruses and other members of Nucleocytoviricota has seen considerable progress. Nucleocytoviricota is a phylum of widely diverse eukaryotic DNA viruses. Several clades of Nucleocytoviricota independently underwent a dramatic expansion of their genomes, becoming the giants of the virus world. At the same time, some recently described Nucleocytoviricota have relatively small genomes (smaller than 40 kbp) with the genome of the last common ancestor of all Nucleocytoviricota estimated to contain less than a dozen genes. This highlights the flexibility of the Nucleocytoviricota’s genomic structure and the plasticity of their molecular biology.
Nucleocytoviricota infect a broad range of hosts and many of them are extremely important for human economy and health. Some Nucleocytoviricota form complex intracellular structures during their life cycle, and they seem to possess a fascinating array of features for interacting with their hosts. Unlike most known viruses, Nucleocytoviricota have their own specific predators, virophages, that form their own satellite universe within the Bamfordvirae kingdom.
This Special Issue surveys the development in the field of Nucleocytoviricota biology, with a special focus on their biodiversity; interaction with their hosts and virophages; and genomic, evolutionary, and ecological perspectives.
We look forward to receiving your contributions.
Dr. Natalya Yutin
Guest Editor
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Keywords
- Nucleocytoviricota
- giant viruses
- virophages
- host–virus (-virophage) interactions
- virion structure
- viral ecology
- diversity and classification
- evolution of Nucleocytoviricota
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