Recent Advances in Toxoplasma gondii Infections
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Infectious Diseases".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 191
Special Issue Editors
Interests: Toxoplasma gondii; host–parasite interaction; toxoplasmosis; neurodevelopment and behavior; drug discovery; treatment efficacy; diagnosis and prevention; co-infections
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
This Special Issue focuses on recent advancements in Toxoplasma gondii infections.
Toxoplasma gondii is an intracellular parasite that is capable of infecting a wide range of hosts, serving as an intermediate for T. gondii to reach its definitive host, felines. Infection with toxoplasma is common, but severe disease does not ensue unless the host is immunosuppressed or immunocompromised. Due to the latent nature of this parasite, studies are ongoing to determine the host–parasite interactions during infection and gain a better understanding of the biology of the parasite for the design of better treatments aimed at eradicating the parasite. The predilection of this parasite to infect the brain and heart remains an area of active investigation. Recent systematic studies suggest the association of toxoplasmosis with neurodevelopmental and neuropsychiatric disorders. At the cellular level, chronic toxoplasmosis has been shown to alter brain connectivity by disrupting neurotransmitter signaling.
There is a need to better understand the toxoplasma biology by understanding the host–parasite interactions that will in turn facilitate the development of effective treatments and prevention strategies for toxoplasmosis. This Special Issue aims to report recent findings in the biology of toxoplasma infections (cell biology, drug discovery, vaccine development neuroinflammation, behavior, pathophysiology of infection, etc.).
Dr. Imaan Benmerzouga
Dr. Marc Benson
Guest Editors
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