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TropicalMed
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Trachoma and Its Management
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Trachoma and Its Management

A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366).

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 1836

Special Issue Editors

Dr. Rebecca Flueckiger

E-Mail Website
Guest Editor
RTI International, Atlanta, GA 30329-4434, USA
Interests: geospatial modeling; maternal and child health; neglected tropical diseases
Dr. Jeremiah Ngondi

E-Mail Website
Co-Guest Editor
RTI International, Atlanta, GA 30329-4434, USA
Interests: trachoma elimination; malaria control and elimination; disease surveillance; population-based health surveys; neglected tropical diseases

Special Issue Information

Dear Colleagues,

This Special Issue entitled "Trachoma and Its Management" presents a comprehensive exploration of current research and strategies aimed at addressing the challenges posed by trachoma in regions where it remains endemic. Encompassing epidemiological studies, innovative interventions, community engagement approaches, and technological advancements, the collection provides a holistic view of the efforts to understand, control, and manage trachoma. From analyzing disease prevalence and risk factors to showcasing effective treatments and emphasizing the crucial role of community involvement and health systems, this Special Issue serves as a valuable resource for policymakers, healthcare professionals, and researchers dedicated to mitigating the impact of trachoma and improving eye health on a global scale.

Dr. Rebecca Flueckiger
Dr. Jeremiah Ngondi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • trachoma
  • neglected tropical diseases
  • epidemiology
  • disease prevalence
  • global eye health

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

12 pages, 2221 KiB  
Article
Correlates of Trachoma Recrudescence: Results from 51 District-Level Trachoma Surveillance Surveys in Amhara, Ethiopia
by Eshetu Sata, Nicholas A. Presley, Phong Le, Andrew W. Nute, Zebene Ayele, Ayalew Shiferaw, Demelash Gessese, Ambahun Chernet, Berhanu Melak, Tania A. Gonzalez, Kimberly A. Jensen, Adisu Abebe Dawed, Taye Zeru, Zerihun Tadesse, Elizabeth Kelly Callahan and Scott D. Nash
Trop. Med. Infect. Dis. 2024, 9(12), 298; https://doi.org/10.3390/tropicalmed9120298 - 5 Dec 2024
Viewed by 319
Abstract
Trachoma recrudescence is a serious concern for trachoma control programs. Programs define recrudescence as the return of trachomatous inflammation-follicular (TF) prevalence above elimination threshold (≥5%) on district-level trachoma surveillance surveys (TSSs). This study aimed to determine potential correlates of trachoma recrudescence within a [...] Read more.
Trachoma recrudescence is a serious concern for trachoma control programs. Programs define recrudescence as the return of trachomatous inflammation-follicular (TF) prevalence above elimination threshold (≥5%) on district-level trachoma surveillance surveys (TSSs). This study aimed to determine potential correlates of trachoma recrudescence within a historically highly endemic region. Between 2015 and 2021, population-based TSSs were conducted in 51 districts of Amhara, Ethiopia. District estimates were calculated accounting for multistage design; logistic regression was used to estimate the association of key correlates with recrudescence at the district level. Among the 51 districts, 17 (33%) were recrudescent. Correlates of recrudescence included indicators of historic trachoma burden, such as higher trachomatous inflammation-intense (TI) prevalence (odds ratio [OR]: 2.6, CI: 1.4–5.3) and higher Chlamydia trachomatis (Ct) infection prevalence (OR: 2.9, CI: 1.1–9.9) at the first recorded impact survey. The increased prevalence of children with clean faces (OR: 0.4, CI: 0.21–1.0) and the increased prevalence of travel time to a water source ≤ 30 min (OR: 0.5, CI: 0.2–1.1) at the TSS were associated with a protective effect from recrudescence. Data on historical trachoma burden as well as current water and sanitation conditions may help programs predict where recrudescence is more likely to occur and thus help programs sustain elimination as a public health problem. Full article
(This article belongs to the Special Issue Trachoma and Its Management)
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8 pages, 184 KiB  
Article
Optimizing Trichiasis Case Finding to Attain the Elimination of Trachoma as a Public Health Problem
by Joy Shu’aibu, Grace Ajege, Caleb Mpyet, Michael Dejene, Sunday Isiyaku, Abubakar Tafida, Michaela Kelly, Innocent Emereuwa and Paul Courtright
Trop. Med. Infect. Dis. 2024, 9(7), 157; https://doi.org/10.3390/tropicalmed9070157 - 11 Jul 2024
Viewed by 802
Abstract
Background: As national trachoma programmes increase efforts to reduce the burden of trachomatous trichiasis (TT), TT case finding and referral are critical public health programme components. Our research aimed to explore the most effective and efficient approaches to finding, referring, and managing TT [...] Read more.
Background: As national trachoma programmes increase efforts to reduce the burden of trachomatous trichiasis (TT), TT case finding and referral are critical public health programme components. Our research aimed to explore the most effective and efficient approaches to finding, referring, and managing TT cases. Methods: This was a prospective descriptive study, utilizing both routine programme data and primary data collection. This study compared four different approaches to finding TT cases across three different local government areas (LGAs) in Kano State, Nigeria. Each of the study LGAs was divided into four sub-units to accommodate the four different approaches. Results: The number of outreach attendees was 4795 across the four case finding approaches, and this varied hugely, with the smallest number and proportion (403, 0.26%) in settings only employing house-to-house case finding and the largest number and proportion (1901, 0.99%) when town criers were used. That said, the proportion of TT cases among people presenting at outreach was highest (32.5%) when house-to-house case finding was used and lowest (10.3%) when town criers were used. More female TT patients were found (53–70%) and had surgery (79–85%) compared to male cases, across all approaches. The average project expenditure for finding one TT case was similar for approaches that included house-to-house case finding (USD 5.4–6.3), while it was 3.5 times higher (USD 21.5 per TT case found) when town criers were used. Discussion: This study found that the house-to-house TT case finding approaches were the most efficient method with the highest yield of TT cases. Including other eye condition and/or vision testing yielded similar results but required more personnel and cost. Full article
(This article belongs to the Special Issue Trachoma and Its Management)
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