Load of HIV, Viral Hepatitis and STIs in the Context of COVID-19 Pandemic

A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Infectious Diseases".

Deadline for manuscript submissions: closed (15 February 2023) | Viewed by 4859

Special Issue Editors


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Guest Editor
Faculty of Nursing, Universidade Federal de Goiás, Goiânia 74690-900, GO, Brazil
Interests: viral hepatitis; STIs; HIV; vulnerable people

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Guest Editor
Federal University of Mato Grosso do Sul and Oswaldo Cruz Foundation, Mato Grosso do Sul, Campo Grande 79081-746, MS, Brazil
Interests: viral hepatitis; STIs; HIV; vulnerable people

Special Issue Information

Dear Colleagues,

HIV, HTLV, viral hepatitis, and sexually transmitted infections (STIs) are important global public health concerns. It is estimated that 1.5 million people acquired HIV in 2020; each year, there are 3.0 million new cases of hepatitis B and C, and 374 million new cases of STIs. These infections cause of a high burden of acute and chronic diseases worldwide, including cancer, infertility in women, and death. The Global Health Sector Strategy reports for 2016–2021 have described advances in the control and prevention of these infections. However, additional measures are needed in order to reach the global target laid out in the UN’s Sustainable Development Goals to eliminate them as public health threats by 2030.

According to the World Health Organization, many health services that are effective at preventing, diagnosing, and treating HIV, viral hepatitis, and STIs have been disrupted or had reduced attendance since the start of the COVID-19 pandemic. In addition, social restriction measures and the fear of acquiring COVID-19 have reduced the demand for care and have had a negative impact on advances in the control and prevention of these diseases. In this issue, we invite submissions presenting different scenarios regarding the potential adverse effects of the COVID-19 pandemic on these diseases, as well as its impact on achieving the UN’s Sustainable Development Goals and the Global Health Sector’s goal to eliminate these diseases as threats to public health by 2030.

Dr. Sheila Teles
Dr. Ana Rita Coimbra Motta-Castro
Guest Editors

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Keywords

  • viral hepatitis
  • sexually transmitted infections
  • HIV
  • epidemiology

Published Papers (3 papers)

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Research

11 pages, 301 KiB  
Article
Impact of COVID-19 Pandemic on Seroprevalence of HIV, HBV, HCV and HTLV I-II in a Blood Bank in Medellín, Colombia, 2019–2022
by Jaiberth Antonio Cardona-Arias and Luis Felipe Higuita-Gutiérrez
Trop. Med. Infect. Dis. 2023, 8(2), 118; https://doi.org/10.3390/tropicalmed8020118 - 14 Feb 2023
Cited by 2 | Viewed by 1565
Abstract
The objective of this research was to analyze the impact of the COVID-19 pandemic on seroprevalence of HIV, HBV, HCV and HTLV I-II in donors from a blood bank in Medellin, Colombia, 2019–2022. A cross-sectional analytical study was carried out with three groups: [...] Read more.
The objective of this research was to analyze the impact of the COVID-19 pandemic on seroprevalence of HIV, HBV, HCV and HTLV I-II in donors from a blood bank in Medellin, Colombia, 2019–2022. A cross-sectional analytical study was carried out with three groups: pre-pandemic with 14,879 donors; preventive isolation with 9035; and selective isolation + new normality with 26,647 subjects. Comparisons were made with Chi2 and Bonferroni adjustment, Kruskal–Wallis’ H with Dunnett’s post-hoc, prevalence ratios, and multivariate logistic regression. COVID-19 decreased donations of men, altruistic and repetitive donors, and increased the age of donors. HIV increased with the COVID-19 pandemic, while HBV, HCV, and HTLV I-II decreased. The pandemic had an independent effect on these viral infections. These findings constitute an alert about what may be happening in the general population and show the importance of improving epidemiological surveillance and the investigation of these infections. Full article
12 pages, 695 KiB  
Article
Health-Related Quality of Life, Pain and Sleep in Patients with HIV Depending on the Clinical Situation: A Cross-Sectional Pilot Study
by Jon Salmanton-García, Francisco Alburquerque-Sendín, Javier Martín-Vallejo, Alicia Iglesias-Gómez and Miguel Cordero-Sánchez
Trop. Med. Infect. Dis. 2022, 7(12), 409; https://doi.org/10.3390/tropicalmed7120409 - 30 Nov 2022
Cited by 1 | Viewed by 1173
Abstract
Introduction: Health-related quality of life (HRQL), pain and sleep have been described as relevant traits in patients with human immunodeficiency virus (HIV). The aim of this study is to describe and evaluate HRQL, pain and sleep and their interdependence in HIV-positive patients. Methods: [...] Read more.
Introduction: Health-related quality of life (HRQL), pain and sleep have been described as relevant traits in patients with human immunodeficiency virus (HIV). The aim of this study is to describe and evaluate HRQL, pain and sleep and their interdependence in HIV-positive patients. Methods: A cross-sectional study on HIV-infected patients was conducted. A set of five different questionnaires was used: two questionnaires addressing HRQL (Short Form 36 [SF-36] Health Survey and Medical Outcomes Study Short Form 30 [MOS-SF 30]), one on pain (McGill Pain Questionnaire) and one on sleep (Pittsburgh Sleep Quality Index [PSQI]). We also collected the sociodemographic and clinical characteristics of patients. Results: The sample included 109 patients (age: 46.08 ± 10.49 years; 68.8% male). The pain experience was independent of HRQL and sleep. Relationships among HRQL, pain and sleep associated to sociodemographic and clinical factors were not detected (p > 0.05). Patients with CDC category A showed moderate to high correlations among HRQL, pain and sleep. In CDC B-type patients, a moderate correlation was observed between pain and mental health. In CDC C patients, moderate correlations were observed between HRQL and sleep and pain and sleep, with no correlations between HRQL and pain. Conclusions: HRQL, pain and sleep are differently correlated in HIV patients depending on their clinical stage. Neither the nadir of CD4-T cells nor the current count of CD4-T cells was found to be related with HRQL, pain or sleep. Full article
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11 pages, 619 KiB  
Article
Viral Hepatitis A, B and C in a Group of Transgender Women in Central Brazil
by Lucila Pessuti Ferri, Priscilla dos Santos Junqueira, Mayara Maria Souza de Almeida, Mariana Gomes Oliveira, Brunna Rodrigues de Oliveira, Bruno Vinícius Diniz e Silva, Larissa Silva Magalhães, Lívia Melo Villar, Karlla Antonieta Amorim Caetano, Márcia Maria Souza, Megmar Aparecida dos Santos Carneiro, Regina Maria Bringel Martins and Sheila Araujo Teles
Trop. Med. Infect. Dis. 2022, 7(10), 269; https://doi.org/10.3390/tropicalmed7100269 - 27 Sep 2022
Cited by 1 | Viewed by 1733
Abstract
Transgender women (TGW) have limited access to affordable viral hepatitis testing, hepatitis B vaccination, and treatment. We aimed to estimate the prevalence of viral hepatitis A, B, and C, as well as to compare the adherence and immunogenicity of two hepatitis B vaccine [...] Read more.
Transgender women (TGW) have limited access to affordable viral hepatitis testing, hepatitis B vaccination, and treatment. We aimed to estimate the prevalence of viral hepatitis A, B, and C, as well as to compare the adherence and immunogenicity of two hepatitis B vaccine schedules among TGW in Central Brazil. A total of 440 TGW were interviewed and tested for hepatitis A, B, and C serological markers from 2017 to 2018. The hepatitis B vaccine was offered to 230 eligible TGW: 112 received a super accelerated hepatitis B vaccine schedule (G1) and 118 a standard schedule (G2). The antibody against the hepatitis A virus (HAV) was detected in 75.63% of the participants, and 12.3% of the TGW were exposed to the hepatitis B virus (HBV). Two (0.46%) participants were HBV carriers. Only 41.5% of the participants showed a serological profile of hepatitis B vaccination. The antibody against the hepatitis C virus (anti-HCV) was found in six participants (1.37%). Of the TGW who received the first vaccine dose, 62 (55.36%) and 49 (41.52%) in G1 and G2, respectively, received three doses (p = 0.036). The vaccine response was evaluated in 28 G1 and 22 G2 TGW; of these, 89.3% and 100% developed protective anti-hepatitis B surface-antigen titers, respectively (p = 0.113). Since one-third of younger transgender women are susceptible to HAV, hepatitis B immunization is low, and the anti-HCV rate is higher in this group than in the general population in Central Brazil, public-health attention is warranted. The super-accelerated scheme demonstrated better adhesion and good immunogenicity, suggesting that it would be a more cost-effective solution. Full article
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