Novel Insights into the Physiological and Pathological Role of Leptin and Leptin Receptor
A special issue of Receptors (ISSN 2813-2564).
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 131
Special Issue Editors
Interests: breast cancer; glioblastoma; seminoma; obesity; leptin; aromatase
Special Issues, Collections and Topics in MDPI journals
Interests: breast cancer; tumor microenvironment; adipokines; nuclear receptors; ESR1 mutations; endocrine-resistance; exosomes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, research efforts have been expanded to clarify the role of leptin/leptin receptors in human physiology and in the pathophysiology of several disorders. However, more studies are needed to fully elucidate leptin/leptin receptor signaling pathways. The adipocyte-derived factor leptin and its receptor (ObR) are widely expressed in a large spectrum of tissues, wherein they play a pivotal role in energy homeostasis, metabolism, and in neuroendocrine and immune functions. Further, it has been demonstrated that the leptin/leptin receptor signaling pathway is linked to the proliferation, migration, and invasion of cancer cells. Indeed, targeting the leptin/leptin receptor has generated a great amount of interest in the design and development of several modulators that could offer a valuable therapeutic strategy in many diseases.
In this Special Issue, we welcome original research articles, as well as review articles, in order to provide new knowledge about the physiological and pathological significance of leptin/leptin receptors.
You may choose our Joint Special Issue in Biomolecules.
Dr. Salvatore Panza
Dr. Luca Gelsomino
Guest Editors
Manuscript Submission Information
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Keywords
- leptin
- leptin receptor
- metabolic disorders
- obesity
- cancer
