Potential Treatment Targets for Non-alcoholic Liver Disease
A special issue of Medicines (ISSN 2305-6320).
Deadline for manuscript submissions: closed (31 October 2018) | Viewed by 10725
Special Issue Editor
Special Issue Information
Dear Colleagues,
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome (MS) in some or may lead to MS in others and, thus, necessitates a multidisciplinary management approach. In addition, in some cases, it may not be associated with MS and presents as an isolated clinical entity. It is estimated that the global prevalence of NAFLD is over 1 billion. NAFLD affects 80 to 100 million persons in the United States, with up to 15 million developing progressive liver damage resulting in nonalcoholic steatohepatitis (NASH). NASH is the most rapidly rising indication for liver transplantation in the United States. Despite its high prevalence and a significant proportion of NAFLD cases resulting in cirrhosis followed by end-stage liver disease (liver failure), hepatocellular carcinoma, and need for liver transplantation, there are no medications approved for the treatment of NAFLD.
In this Special Issue, we attempt to systematically review current approaches and future prospects to optimize the management of NAFLD.
Prof. Dr. Aijaz Ahmed
Guest Editor
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Keywords
- nonalcoholic fatty liver disease (NAFLD)
- metabolic syndrome (MS)
- nonalcoholic steatohepatitis (NASH)
- end-stage liver disease (liver failure)
- liver transplantation
- chronic liver disease
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