Biomechanical Techniques for Biomedical Imaging

A special issue of Journal of Imaging (ISSN 2313-433X).

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 2921

Special Issue Editors


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Guest Editor
Departamento de Fisica Aplicada, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain
Interests: visual optics; visual perception; biomedical optics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Departamento de Física Aplicada, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain
Interests: visual optics; optical design; optical quality; imaging systems; biomechanics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biomechanical imaging (BMI) has spread during the last decade as a promisng and powerful tool in biomedicine with increasing fields of application. Knowledge of mechanical properties of biological tissues such as elastic modulus, stiffness, viscosity, or viscoelasticity are crucial to understanding the structural integrity and organization that allow mechanobiology to function as a biomarker for distinguishing between health and diseased tissues. Current methods to measure biomechanical properties, such as tridimensional elasticity imaging, ultrasound elastography, and acoustic model-based imaging technologies have demonstrated in vivo biomechanical tridimensional resolution in biomedical imaging. Those imaging techniques have been expanded in parallel with computational and predictive methods in biomechanics for resolving inverse problems of viscoelastic nonlinearity of biological tissues.

We request contributions presenting imaging techniques that will contribute to highlighting the current state of the art in biomechanical imaging as well as computational models contributing to the study of mechanobiology.

Dr. Francisco Avila Gomez
Dr. Laura Remón
Guest Editors

Manuscript Submission Information

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Keywords

  • electronic speckle laser interferometry
  • ultra-sound elastography
  • Brillouin microscopy
  • atomic force microcopy
  • traction force microcopy
  • computational methods in biomechanics
  • acoustic based-method imaging techniques
  • elasticity imaging

Published Papers (1 paper)

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13 pages, 3398 KiB  
Article
On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties
by Francisco J. Ávila, Maria Concepción Marcellán and Laura Remón
J. Imaging 2021, 7(12), 280; https://doi.org/10.3390/jimaging7120280 - 18 Dec 2021
Cited by 2 | Viewed by 2224
Abstract
Optical properties of the cornea are responsible for correct vision; the ultrastructure allows optical transparency, and the biomechanical properties govern the shape, elasticity, or stiffness of the cornea, affecting ocular integrity and intraocular pressure. Therefore, the optical aberrations, corneal transparency, structure, and biomechanics [...] Read more.
Optical properties of the cornea are responsible for correct vision; the ultrastructure allows optical transparency, and the biomechanical properties govern the shape, elasticity, or stiffness of the cornea, affecting ocular integrity and intraocular pressure. Therefore, the optical aberrations, corneal transparency, structure, and biomechanics play a fundamental role in the optical quality of human vision, ocular health, and refractive surgery outcomes. However, the inter-relationships of those properties are not yet reported at a macroscopic scale within the hierarchical structure of the cornea. This work explores the relationships between the biomechanics, structure, and optical properties (corneal aberrations and optical density) at a macro-structural level of the cornea through dual Placido–Scheimpflug imaging and air-puff tonometry systems in a healthy young adult population. Results showed correlation between optical transparency, corneal macrostructure, and biomechanics, whereas corneal aberrations and in particular spherical terms remained independent. A compensation mechanism for the spherical aberration is proposed through corneal shape and biomechanics. Full article
(This article belongs to the Special Issue Biomechanical Techniques for Biomedical Imaging)
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