Special Issue "Conserved and Divergent Mechanisms Regulating Muscle Development and Regeneration"
A special issue of Journal of Developmental Biology (ISSN 2221-3759).
Deadline for manuscript submissions: closed (31 December 2019).
Interests: skeletal muscle; mouse molecular genetics; muscle stem cells; myogenesis; development
Skeletal muscle shows robust regenerative capacity and is able to undergo several rounds of regeneration in response to multiple injuries. This capacity depends on satellite cells, the stem cells of the adult muscle. During regeneration, satellite cells proliferate and differentiate to form new muscle tissue, but they also self-renew to maintain the satellite cell pool. Muscle Stem cells originate from a pool of embryonic/fetal progenitors. Satellite cells and muscle progenitor cells share features like Pax7 expression, the ability to self-renew or to differentiate, and are thought to rely on similar molecular mechanisms for differentiation. Thus, the analysis of developmental processes can guide satellite cell research. Yet, differences in molecular mechanisms have also become apparent. This Special Issue of the Journal of Developmental Biology will provide an overview of the current understanding of skeletal muscle stem development and regeneration, focusing on conserved and divergent mechanisms Contributions can be reviews, as well as research papers, covering comparative analysis of development and regeneration of skeletal muscle.
Prof. Dr. Frederic Relaix
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- skeletal muscle
- muscle stem cells