Special Issue "Development of the Brain in Health and Disease"
A special issue of Journal of Developmental Biology (ISSN 2221-3759).
Deadline for manuscript submissions: closed (31 August 2017).
Interests: neural tube closure; birth defects; folate metabolism; gene-environment interactions; mouse development
The development of the brain depends on specification of the neuroepithelium, regulated tissue movements to generate the closed neural tube and patterning of the dorso-ventral and anterior-posterior axes. Subsequent coordinated growth, timely differentiation of appropriate cell types at precise positions, and establishment of connectivity are essential for brain function. Abnormalities during these developmental processes can lead to structural birth defects, such as holoprosencephaly, neural tube defects, and microcephaly, as well as later functional deficits manifesting as neurological impairment, intellectual disability and epilepsy. The detailed mechanisms underlying these highly complex processes are still the subject of intense research of importance both in understanding the fundamental process in development and the mechanisms underlying disease. This Special Issue of the Journal of Developmental Biology is intended to provide an overview of current progress in this large research field. Contributions can include original research papers or reviews.
Prof. Dr. Nicholas D.E. Greene
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- neural differentiation
- neuronal migration
- brain development
- birth defects
- central nervous system
- neural tube
- neural crest