Advances in Zebrafish Cardiac Disease Models

Dear Colleagues,

Heart diseases such as hypertrophy and heart attack represent the most frequent causes of death in humans. Several research groups worldwide are currently studying the cellular, genetic and molecular mechanisms underlying the onset of cardiovascular diseases to find effective and targeted therapies for individual patients. In this context, studies in alternative animal models, IPSC and organoids can be conducted to investigate repair strategies for human heart tissues. Furthermore, such studies can teach us which repair mechanisms or drugs are potentially effective. Even stochastic mechanisms that underlie the phenotypic differentiation/regeneration of cardiomyocytes could be approached by spatially resolved gene expression profiling and lineage analysis. An elective model used in the last 20 years for studying cell biology and cardiac development/repair and disease is the zebrafish (Brachidanio rerio). This Special Issue aims to expose new and emergent research in the field of cardiac regeneration and the control of pathologies by using alternative models such as the zebrafish.

Dr. Nicla Romano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Dr. Nicla Romano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• zebrafish
• heart
• cardiomyocytes
• heart disease
• cardiac hypertrophy
• regenerative medicine
• cardiac regeneration
• translational models