Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers
A special issue of Journal of Clinical & Translational Ophthalmology (ISSN 2813-1053).
Deadline for manuscript submissions: 20 March 2026 | Viewed by 3
Special Issue Editors
Interests: neuroscience; vision science; optometry and vision science; optics; astigmatism; visual perception; retina
Special Issues, Collections and Topics in MDPI journals
Interests: neuro-ophthalmology; neural health and surgical outcomes; neural diagnostics and interventions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The pupil plays a pivotal role in visual performance and clinical diagnostics, functioning as both an optical modulator and a non-invasive biomarker of ocular and systemic health. Variations in pupil size and dynamics directly influence depth of focus, retinal image quality, and the success of vision-enhancing interventions, including intraocular lens (IOL) implantation, corneal inlays, small-aperture optics, and pharmacologic treatments for presbyopia. At the same time, pupil responsiveness offers valuable diagnostic information in neuro-ophthalmology and general medicine, particularly for detecting early signs of neurological and systemic disorders.
This Special Issue will explore the clinical implications of pupil function across a range of diagnostic, pharmacological, and surgical applications. Topics of interest include the effect of pupil size on visual quality and acuity; optimization of multifocal and small-aperture IOLs; surgical outcomes influenced by pupil dynamics; pharmacologic modulation of the pupil; pupillometry in disease detection; and age-related changes in iris biomechanics.
We welcome original research, reviews, and clinical studies from ophthalmology, optometry, neuro-ophthalmology, and vision science. By bridging optical mechanisms with translational and clinical practice, this Special Issue will highlight how understanding and managing pupil behavior can enhance both visual outcomes and systemic health assessment.
You may choose our Joint Special Issue in JCM.
Dr. Pablo De Gracia
Dr. Héctor E. Soriano Baron
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical & Translational Ophthalmology is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pupil function
- visual performance
- intraocular lens (IOL) optimization
- pupillometry diagnostics
- neuro-ophthalmic biomarkers
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