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Rehabilitation Approaches to Reduce Frailty and Promote Healthy Aging

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Care Sciences".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 913

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Guest Editor
Department of Medicine and Physiotherapy, Postgraduate Program in Health and Behavior, Catholic University of Pelotas (UCPEL), Pelotas 96015-560, Brazil
Interests: intensive care units; critical illness; frailty and elderly patients
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Special Issue Information

Dear Colleagues,

Frailty Syndrome is a clinical condition of genetic and neuroendocrine origin, causing greater vulnerability to diseases or acute stress in the elderly, and is characterized by reduced muscle mass and strength and low energy when carrying out daily activities.

The phenotype of this syndrome described by Fried is considered the gold standard for diagnosis and has five components: unintentional weight loss (greater than or equal to 4.5 kg in the last year), a feeling of exhaustion, physical inactivity, a low walking speed, and decreased grip strength. Individuals displaying one or two positive features are characterized as pre-frail, and those displaying more than two are considered frail. The most common symptoms are involuntary weight loss, weakness, a reduced walking speed, and exhaustion.

It is important to note that no specific rehabilitation approach has yet been determined to treat Frailty Syndrome as a whole; however, physical exercise remains one of the best options to increase muscle mass.

Recent studies have shown that with an appropriate physical rehabilitation program, it is possible to prevent or even reverse frailty. There is a consensus that physical activity is the best treatment for frailty in older adults, but none on the ideal type of exercise. Recent reviews indicate that multicomponent modalities are the most often recommended, with the most frequently cited practices being resistance exercises and balance training. Such initiatives aim to promote healthy aging and have increased the life expectancy in this population.

It is important to highlight the impact of frailty on this population’s quality of life, as well as their participation in the workplace. This fragility not only translates into greater difficulty in dealing with certain occupational risks but also a greater likelihood of suffering violence and aggression or being excluded from the labor market. Furthermore, loneliness in older people is often related to their frailty. All these phenomena have a major impact on public health, and addressing them requires not only treatment but also health promotion initiatives.

Therefore, this Special Issue will compile studies that report on treatment, rehabilitation, and prevention strategies for managing Frailty Syndrome.

Dr. Luiz Alberto Forgiarini-Júnior
Guest Editor

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Keywords

  • frailty syndrome
  • rehabilitation
  • aging
  • health promotion
  • physiotherapy

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Published Papers (1 paper)

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Research

14 pages, 2980 KB  
Article
Frailty and Socioeconomic Development in the European Region—Associations with Mortality in Middle-Aged and Older Adults
by Rónán O’Caoimh, Aoife Wall and Mark R. O’Donovan
Int. J. Environ. Res. Public Health 2026, 23(3), 307; https://doi.org/10.3390/ijerph23030307 - 28 Feb 2026
Viewed by 481
Abstract
The Sociodemographic Index (SDI) captures a country’s or region’s relative socioeconomic development and has been linked to age-related disease burden and life expectancy. Frailty is a multidimensional geriatric syndrome associated with adverse health outcomes and mortality. This study examined the relationship between country-level [...] Read more.
The Sociodemographic Index (SDI) captures a country’s or region’s relative socioeconomic development and has been linked to age-related disease burden and life expectancy. Frailty is a multidimensional geriatric syndrome associated with adverse health outcomes and mortality. This study examined the relationship between country-level SDI, frailty prevalence, and mortality across Europe. We conducted a secondary analysis of community-dwelling adults aged 50 years and older from 12 countries participating in the Survey of Health, Ageing and Retirement in Europe (SHARE). Frailty status and SDI were assessed at Wave 2 (2007), with mortality follow-up at Wave 4 (2011). Countries were categorised into lower- and higher-SDI groups using the median as a cut-off. Frailty was measured using a 70-item frailty index (FI ≥ 0.25) and a modified Fried frailty phenotype (FP ≥ 3 criteria). Frailty prevalence varied substantially by country and assessment method, ranging from 7 to 40% using the FI and 4–21% using the FP. Prevalence was lowest in Switzerland and highest in Poland and was strongly correlated with national SDI scores (r ≥ 0.8). After adjustment for age and sex, lower SDI was independently associated with higher odds of frailty using both frailty measures. Although mortality was lower in higher-SDI countries, this association was not statistically significant after adjusting for age, sex, and frailty. Lower social development was strongly associated with frailty prevalence but did not independently predict mortality, highlighting frailty as a potential pathway linking social context to later-life health outcomes in Europe. Full article
(This article belongs to the Special Issue Rehabilitation Approaches to Reduce Frailty and Promote Healthy Aging)
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