Containment Strategies of Infectious Diseases: Epidemiology, Surveillance and Prophylaxis

A special issue of Infectious Disease Reports (ISSN 2036-7449). This special issue belongs to the section "Infection Prevention and Control".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 912

Special Issue Editors


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Guest Editor
Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”/DIPMED, University of Salerno, Baronissi, 84081 Salerno, Italy
Interests: hygiene; prophylaxis; healthcare-associated infections; microbiology; clinical pathology; antibiotic resistance
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”/DIPMED, University of Salerno, Baronissi, 84081 Salerno, Italy
Interests: microbiology and virology; antimicrobial stewardship; medicine; epigenetic; drug discovery; alert germs
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Clinical Pathology and Microbiology Unit, San Giovanni di Dio and Ruggi D'Aragona University Hospital, 84131 Salerno, Italy
Interests: microbiology and virology; arboviruses; infectious disease; antimicrobial resistance; drug discovery; epigenetic, public health; hygiene; prophylaxis; healthcare-associated infections; surveillance

Special Issue Information

Dear Colleagues,

The burden of infectious diseases on public health, the global economy, and healthcare systems is an overwhelming challenge that we have clearly understood through the recent SARS-CoV-2 pandemic, which caused 5.89 million deaths in 2020 and 9.97 million deaths in 2021 worldwide. Increasingly widespread cases are being reported for West Nile Virus, Dengue, Zika, and Monkeypox infections. On the other hand, Mycobacterium tuberculosis resistant to rifampicin and third-generation cephalosporin/carbapenem-resistant Enterobacterales strains in 2024 have become part of the WHO list of “high-priority pathogens”. Indeed, the phenomenon of antibiotic resistance (AMR) is estimated to cause 10 million deaths annually by 2050, underscoring the urgent need for targeted interventions. Last but not least, Candida auris represents a growing threat due to its resistance to many drugs, biofilm formation ability and lethality in invasive forms.

The Special Issue "Containment Strategies of Infectious Diseases: Epidemiology, Surveillance and Prophylaxis", will feature articles focused on preventive measures to manage infections through the robust identification of 'alert' pathogens and epidemic clusters, targeted epidemiological surveillance, and the development and implementation of effective cleansing and sanitization procedures for the decontamination of critical clinical environments, objects, and medical devices.

Manuscripts structured as reviews, original research articles, brief communications, and case reports on this topic will be considered by the editorial team and evaluated for suitability for peer review.

The goal of this Special Issue of Infectious Disease Reports is to share information on new strategies for containing infections in community and nosocomial settings and to evaluate the effectiveness of vaccination campaigns, aiming for a multidisciplinary approach from a public health perspective. This will enable a greater awareness of evolving local realities to improve the management and prevention of future threats.

Dr. Giovanni Boccia
Dr. Gianluigi Franci
Dr. Enrica Serretiello
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Infectious Disease Reports is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hygiene
  • prophylaxis
  • environmental monitoring
  • travel medicine
  • global health
  • molecular diagnosis
  • prevention
  • food transmission disease
  • zoonosis
  • parasitosis
  • fungal infections
  • epidemic/endemic
  • nosocomial infection
  • microbiology
  • virology
  • AMR

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Published Papers (1 paper)

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Review

16 pages, 648 KB  
Review
Clean to Prevent, Monitor to Protect: A Scoping Review on Strategies for Monitoring Cleaning in Hospitals to Prevent HAIs
by Biagio Santella, Antonio Donato, Luigi Fortino, Vittoria Satriani, Rosaria Flora Ferrara, Emanuela Santoro, Walter Longanella, Gianluigi Franci, Mario Capunzo and Giovanni Boccia
Infect. Dis. Rep. 2025, 17(5), 120; https://doi.org/10.3390/idr17050120 - 21 Sep 2025
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Abstract
Background/Objectives: Hospital environmental contamination represents a significant source of healthcare-associated infections, yet standardized monitoring approaches are still inconsistent globally. This scoping review aimed to find and assess various tools and strategies used to monitor hospital environmental cleaning and disinfection practices, mapping current evidence [...] Read more.
Background/Objectives: Hospital environmental contamination represents a significant source of healthcare-associated infections, yet standardized monitoring approaches are still inconsistent globally. This scoping review aimed to find and assess various tools and strategies used to monitor hospital environmental cleaning and disinfection practices, mapping current evidence and finding research gaps to inform evidence-based recommendations for healthcare facilities. Methods: Following PRISMA Scoping Review guidelines, we conducted comprehensive searches on PubMed and Scopus databases from 2010–2025 using terms related to environmental monitoring, surface sampling, air sampling, and infection control in hospital settings. Eighteen studies met inclusion criteria; data were extracted using standardized forms and synthesized narratively, organizing findings by monitoring approach categories. Results: These studies revealed diverse monitoring approaches including fluorescent markers (22.2%), ATP bioluminescence assays (33.3%), microbiological methods (44.4%), and direct observation techniques (27.8%). MRSA was the most frequently targeted pathogen (55.6%), with limited attention to Gram-negative multidrug-resistant organisms and fungi. Studies showed significant variability in pass/fail thresholds (ATP: 50–500 RLU) and lack of standardized benchmarks. Recent research (50% post-2021) increasingly incorporates molecular techniques and digital technologies, though implementation remains resource intensive. Conclusions: A multimodal approach combining visual inspection, ATP assays, and microbiological methods appears most effective for comprehensive environmental monitoring. Critical gaps include lack of standardized thresholds, limited pathogen diversity focus, and insufficient integration of emerging digital technologies. Future research should focus on setting universal standards, expanding pathogen coverage, and assessing cost-effective monitoring strategies, all while ensuring legal compliance with hygiene regulations to enhance patient safety. Full article
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