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Healthcare
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Gynecological Cancer: Screening, Prevention and Treatment
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Gynecological Cancer: Screening, Prevention and Treatment

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 3 August 2026 | Viewed by 989

Special Issue Editors

Dr. Ottavia D'Oria

E-Mail Website
Guest Editor
Obstetrics and Gynecological Unit, Department of Woman’s and Child’s Health, San Camillo-Forlanini Hospital, 00152 Rome, Italy
Interests: gynecological oncology; gynecological ultrasound; cancer screening
Special Issues, Collections and Topics in MDPI journals
Dr. Andrea Giannini

E-Mail Website
Guest Editor
Unit of Gynecology, Sant'Andrea Hospital, Department of Surgical and Medical Sciences and Translational Medicine, Sapienza University of Rome, 00189 Rome, Italy
Interests: gynecologic oncology; endometrial cancer; gynecologic surgery; ovarian cancer; cervical cancer
Special Issues, Collections and Topics in MDPI journals
Dr. Tullio Golia D’Augè

E-Mail Website
Guest Editor
Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Policlinico Umberto I, 00161 Rome, Italy
Interests: gynecological oncology; endometrial cancer; gynecological surgery; ovarian cancer; cervical cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will consolidate contemporary knowledge, disseminate innovative methodologies, and foster interdisciplinary research aimed at the prevention of gynecological neoplasms. Gynecological cancers represent a significant global health challenge for women. Despite advancements in diagnostic and therapeutic modalities, prevention remains pivotal in combating these malignancies. The imperative to prevent gynecological tumors arises from their substantial incidence and mortality rates, positioning these cancers as a major global health concern. Many gynecological cancers are preventable through interventions such as early screening and vaccination, underscoring the critical role of prevention in mitigating the burden of these diseases. These malignancies profoundly affect women's health, exacerbate healthcare disparities, and impose considerable economic and societal costs.

We are pleased to invite you to contribute your original research articles and reviews to this Special Issue, which focuses on advancing the prevention of gynecological tumors through innovative strategies, interdisciplinary research, and the consolidation of contemporary knowledge.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Epidemiology of gynecological cancers;
  • Preventive screening programs;
  • Vaccination strategies;
  • Molecular and genetic risk factors;
  • Public health initiatives;
  • Socioeconomic and healthcare disparities;
  • Innovative preventive interventions;
  • Interdisciplinary approaches;
  • Economic impact studies;
  • Educational and awareness programs.

We look forward to receiving your contributions.

Dr. Ottavia D'Oria
Dr. Andrea Giannini
Dr. Tullio Golia D’Augè
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gynecological cancer prevention
  • screening programs
  • HPV vaccination
  • epidemiology of gynecological tumors
  • genetic risk factors
  • public health strategies
  • healthcare disparities in cancer prevention

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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Article
Barriers and Predictors of HPV Vaccine Uptake Among Female Medical Students in Saudi Arabia: A Multi-Center Cross-Sectional Study
by Hanadi Bakhsh, Sarah Ali Altamimi, Falak Nasser Aldosari, Lujain Hatim Aljohani, Sarah Abdulrahman Alali, Nujud Ibrahim Almutlaq, Norah Khalid Alrusaini, Shuruq Munif Alshammari, Yara Abdulaziz Alsuhaibani and Shatha Abdulwahab Alshehri
Healthcare 2025, 13(19), 2408; https://doi.org/10.3390/healthcare13192408 - 24 Sep 2025
Abstract
Background/Objectives: Low HPV vaccine uptake persists in Saudi Arabia despite improving awareness. This study aimed to assess the level of awareness, knowledge, and uptake of the human papillomavirus (HPV) vaccine among female medical students in Saudi Arabia, and to identify key demographic, academic, [...] Read more.
Background/Objectives: Low HPV vaccine uptake persists in Saudi Arabia despite improving awareness. This study aimed to assess the level of awareness, knowledge, and uptake of the human papillomavirus (HPV) vaccine among female medical students in Saudi Arabia, and to identify key demographic, academic, and informational factors that predict vaccination behavior. It also sought to explore perceived barriers influencing vaccine acceptance within this population. Methods: A multi-center cross-sectional survey recruited 246 female medical students from five Saudi universities using convenience sampling. An anonymous, structured, and validated questionnaire assessed HPV/vaccine knowledge, attitudes, uptake, and perceived barriers. Data were analyzed using descriptive statistics, t-tests, ANOVA, correlation, and logistic regression. Results: Overall, 82.9% of participants had heard of HPV and 78.9% knew of the vaccine, but only 10.3% demonstrated high vaccine-specific knowledge. While 69.5% expressed willingness to be vaccinated, only 22.8% had received at least one dose. The most reported barriers were perceived lack of necessity (45.3%), abstinence from sexual activity (41.3%), and safety concerns (34.7%). Logistic regression indicated that higher academic year and higher vaccine-specific knowledge significantly predicted vaccine uptake (p < 0.001). Conclusions: Despite high general awareness, low vaccine-specific knowledge and cultural framing constrain HPV vaccine uptake among future prescribers. Universities should integrate cancer-prevention framing into curricula, strengthen female-to-female counseling, and provide on-campus vaccination opportunities. Addressing knowledge gaps and sociocultural barriers is critical to improving HPV vaccine coverage in Saudi Arabia. Full article
(This article belongs to the Special Issue Gynecological Cancer: Screening, Prevention and Treatment)
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20 pages, 352 KB  
Article
Emotional, Cognitive, and Social Factors Influencing Romanian Women’s Intention to Undergo Cervical Cancer Screening: A Mixed-Method Study
by Nicoleta-Monica Pașca, Diana Taut, Sebastian Pintea and Adriana-Smaranda Băban
Healthcare 2025, 13(17), 2147; https://doi.org/10.3390/healthcare13172147 - 28 Aug 2025
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Abstract
Objective: To identify emotional, cognitive, and social factors associated with Romanian women’s intention to undergo cervical cancer screening (CCS). Methods: An online, cross-sectional, mixed-method survey was conducted among Romanian women. Quantitative statistics were performed to uncover associations, while inductive content thematic analysis was [...] Read more.
Objective: To identify emotional, cognitive, and social factors associated with Romanian women’s intention to undergo cervical cancer screening (CCS). Methods: An online, cross-sectional, mixed-method survey was conducted among Romanian women. Quantitative statistics were performed to uncover associations, while inductive content thematic analysis was used to refine results. Results: 317 women responded. Previous history of CCS (OR = 7.564, CI = 3.523–16.241, p < 0.001), testing positive for HPV strains (OR = 30.176, CI = 1.828–498.049, p < 0.001), knowing that the infection can cause CC (OR = 4.398, CI = 1.117–14.994, p < 0.017), believing the infection is asymptomatic (OR = 2.919, CI = 0.883–8.411, p = 0.04 and being aware of the HPV vaccine (OR = 5.56, CI = 1.722–16.649, p = 0.002 were associated with the intention to undergo screening. Fear of receiving a cancer diagnosis (OR = 2.727, CI = 1.291–5.764, p = 0.009) was associated with higher intention to undergo screening, while shame and feelings of violated privacy negatively impacted the intention. High perceived chances of being infected (OR = 3.38, p = 0.002) and perceiving CCC as beneficial (OR = 7.634, p < 0.001) drove respondents to pursue CCS. Doctor’s recommendation (OR = 15.357) and partner’s support were associated with the intention to pursue CCS when anticipating an HPV infection (OR = 6.016, CI = 2.808–12.888, p < 0.001) or a diagnosis of CC (OR = 4.794, CI = 2.267–10.139, p < 0.001). When anticipating a diagnosis of CC, guilt (OR = 2.557) and fear of dying (OR = 2.253) were significant factors impacting women’s intention to screen. Qualitative analyses uncovered limited knowledge regarding HPV, a lack of awareness about the CCS’s advantages, low perceived susceptibility, and financial burden as factors deterring women from screening. Fear, responsibility, and previous personal or family history of cancer or symptoms were the main drivers motivating participants to engage in CCS. Conclusions: Findings highlighted key emotional, cognitive, and social factors that influence Romanian women’s intention to undergo CCS. This analysis can serve as a foundational support for developing future tailored interventions designed to address low addressability within the targeted population, especially as Romania is in a nascent state of creating population-based screening programs. Full article
(This article belongs to the Special Issue Gynecological Cancer: Screening, Prevention and Treatment)
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