Advancing Quality of Life Research in Cancer Survivors: Methodologies, Instruments, and Practical Applications

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: closed (30 June 2025) | Viewed by 416

Special Issue Editors


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Guest Editor
1. Division of Population Health and Applied Health Sciences, Memorial University of Newfoundland, St. John’s, NL A1B 3V6, Canada
2. Centre for New Immigrant Wellbeing, Markham, ON L3R 9V1, Canada
3. Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada
Interests: cancer epidemiology; COVID-19; arthritis and disability epidemiology; immigrants health; nutritional epidemiology; statistics modeling; hepatitis epidemiology; quality of life; survey methods

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Guest Editor
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden
Interests: cardiovascular diseases; cognitive aging; cohort studies; dementia; diabetes mellitus; diet; epidemiology; geriatrics; neurodegenerative diseases

Special Issue Information

Dear Colleagues,

Quality of Life (QoL) has become a prominent issue in fields such as clinical medicine, health services, social science, and outcomes research. In cancer care, QoL assessments go beyond survival rates and reflect the broader impacts of cancer on patients' physical, emotional, and social well-being. This Special Issue aims to reflect the latest advancements in this field, providing insights into how QoL metrics can enhance patient care and healthcare outcomes.

We welcome high-quality research articles, theoretical discussions, and methodological reports related to Health-Related Quality of Life (HRQL) in cancer survivors. This Special Issue will address various aspects of the field, including the development and validation of new instruments in diverse populations, patient-oriented research, and site-specific cancer explorations. We particularly welcome the submission of papers that address the QoL aspects of treatment, care, and rehabilitation, reflecting the extensive application of HRQL assessments in healthcare.

In addition to original research, we welcome the submission of review papers, editorials, and educational articles that offer guidance for junior researchers and practitioners. This Special Issue seeks to contribute to the field by offering cutting-edge insights that are applicable across the biological and social sciences.

We look forward to receiving your contributions.

Prof. Dr. Peizhong Peter Wang
Prof. Dr. Weili Xu
Guest Editors

Manuscript Submission Information

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Keywords

  • cancer survivors
  • quality of life (QoL)
  • health-related quality of life (HRQL)
  • patient-reported outcomes
  • psychosocial factors
  • cancer care and rehabilitation
  • instrument validation
  • methodological approaches
  • survivorship care
  • health disparities

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Published Papers (1 paper)

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Review

29 pages, 643 KiB  
Review
Psychological Distress and Quality of Life in Patients with Laryngeal Cancer: A Review
by Maria Octavia Murariu, Eugen Radu Boia, Adrian Mihail Sitaru, Cristian Ion Mot, Mihaela Cristina Negru, Alexandru Cristian Brici, Delia Elena Zahoi and Nicolae Constantin Balica
Healthcare 2025, 13(13), 1552; https://doi.org/10.3390/healthcare13131552 - 29 Jun 2025
Viewed by 133
Abstract
Laryngeal cancer significantly affects not only survival but also core functions such as speech, swallowing, and breathing. These impairments often result in substantial psychological distress and reduced health-related quality of life (HRQoL). This review aims to synthesize current evidence regarding the psychological impact, [...] Read more.
Laryngeal cancer significantly affects not only survival but also core functions such as speech, swallowing, and breathing. These impairments often result in substantial psychological distress and reduced health-related quality of life (HRQoL). This review aims to synthesize current evidence regarding the psychological impact, quality of life outcomes, and system-level challenges faced by laryngeal cancer patients while identifying strategies for integrated survivorship care. Anxiety and depressive symptoms are highly prevalent among laryngeal cancer patients, particularly those undergoing total laryngectomy or chemoradiotherapy. HRQoL outcomes vary significantly depending on treatment modality, with long-term deficits noted in domains such as voice, swallowing, and emotional well-being. Access to psychological support and rehabilitation remains inconsistent, hindered by institutional, socioeconomic, and cultural barriers. Structured survivorship models, psychological screening, and patient-centered rehabilitation have demonstrated benefits but are not universally implemented. Comprehensive care for laryngeal cancer must extend beyond tumor control to address persistent functional and psychological sequelae. A multidisciplinary, anticipatory, and personalized approach—centered on integrated rehabilitation and mental health support—is essential to optimize survivorship outcomes and improve long-term quality of life. Full article
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