Diagnosis and Treatment of Dermatological Diseases

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 29 August 2024 | Viewed by 817

Special Issue Editor


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Guest Editor
Department of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland
Interests: nail diseases; onychopathology; dermatopathology; dermatological surgery; diseases of the oral mucosa; aesthetic dermatology
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Special Issue Information

Dear Colleagues,

The skin is the body‘s largest organ. It protects us against our environment and keeps us—literally—in shape. Without the particular structure of the very thin outer layer of our epidermis, the horny layer or stratum corneum, we would not be able to live outside water. The skin is also a mirror of our own internal world and is often claimed to reflect our soul. Blushing and stress-induced sweating are classical examples of the latter; paleness, exaggerated pigmentation, icterus, and many infections are examples of the former. These phenomena may give a first hint towards an internal disease that had hitherto not been recognized.

Not only is the skin the most frequent site for benign and malignant tumours, it may also signal the presence of an internal neoplasm when developing a  paraneoplastic dermatosis. On the other hand, a genuine skin dermatosis may have a serious impact on many internal organs, as is evidenced by the so-called metabolic syndrome observed more and more frequently in psoriasis. The skin is probably the most frequent organ to be affected by allergic reactions to endogenous and exogenous allergens, and allergies are increasing in prevalence and severity.

This Special Issue welcomes both original and review scientific articles relating to the diagnosis and treatment of innumerable conditions, from cosmetic to life-threatening, that are able to interfere with the integrity of our skin.

Prof. Dr. Eckart Haneke
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skin care
  • nail care
  • skin disease
  • inflammation
  • dermatopathology
  • onychopathology
  • paraneoplastic dermatosis
  • atopic dermatitis
  • eczema
  • psoriasis
  • contact dermatitis
  • actinic keratosis
  • acne
  • allergies
  • tumour
  • melanoma

Published Papers (1 paper)

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Research

10 pages, 727 KiB  
Article
Assessment of Standard Surgical Excision Efficacy and Analysis of Recurrence-Associated Factors in 343 Cases of Nasal Basal Cell Carcinoma: A Single-Center Retrospective Study
by Karolina Baltrušaitytė, Ernest Zacharevskij, Loreta Pilipaitytė, Kęstutis Braziulis and Arūnas Petkevičius
Healthcare 2024, 12(5), 513; https://doi.org/10.3390/healthcare12050513 - 21 Feb 2024
Viewed by 604
Abstract
In Caucasians, basal cell carcinoma, the predominant non-melanoma skin cancer type, poses challenges for surgeons due to anatomical and aesthetic concerns, particularly when located on the nose. The study aimed to evaluate tumor distribution, size, morphological subtypes, surgical outcomes, radicality levels, and their [...] Read more.
In Caucasians, basal cell carcinoma, the predominant non-melanoma skin cancer type, poses challenges for surgeons due to anatomical and aesthetic concerns, particularly when located on the nose. The study aimed to evaluate tumor distribution, size, morphological subtypes, surgical outcomes, radicality levels, and their correlation with recurrence rates. A retrospective analysis encompassed 343 cases of nasal skin cancer over a four-year period from 1 January 2019 to 31 December 2022. The research cohort comprised 252 female and 91 male participants, averaging 75.2 years old. Tumors were most found on the left sidewall of the nose (25.4%) and the dorsum (24.8%). The infiltrative morphological subtype was predominant (70.8%). Standard surgical excision with fasciocutaneous plastic was the preferred surgical procedure. Radical excision, defined by the absence of tumor cells in a resection margin, was accomplished in 79.0% of lesions, whereas 16.9% demonstrated incomplete excision, signifying the presence of tumor cells in the resection margin. Non-radically excised tumors exhibited a significantly higher recurrence rate (24.1%) compared to those with radical excision (6.3%). In nasal reconstruction, diverse surgical techniques are essential for precise adaptation based on factors like tumor characteristics and patient needs. Despite surgeons’ careful adherence to excision margin guidelines, the possibility of non-radical outcome cannot be eliminated. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Dermatological Diseases)
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