Innovative Exercise-Based Approaches for Chronic Condition Management

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Health Assessments".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 369

Special Issue Editor


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Guest Editor
1. Prevention and Health in Exercise and Sport (PHES) Research Group, Department of Physical Education and Sports, University of Valencia, 46010 Valencia, Spain
2. Research Institute on Traffic and Road Safety (INTRAS), University of Valencia, Serpis 29, 46022 Valencia, Spain
Interests: physical activity; exercise; ocular health; cardiovascular health; resistance training
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Special Issue Information

Dear Colleagues,

The rising prevalence of chronic diseases, dependence, sedentary lifestyles, and mental health challenges has underscored the critical need for effective, non-pharmacological health interventions. Exercise-based interventions have emerged as a powerful tool in promoting health, preventing disease, and managing a wide range of conditions, including cardiovascular and ocular disease, diabetes, obesity, and depression.

We are pleased to invite you to contribute to the Special Issue "Innovative Exercise-Based Approaches for Chronic Condition Management". This Special Issue aims to explore the latest research, innovative strategies, and clinical applications of exercise as a key component in health management. By gathering insights from interdisciplinary experts, this Special Issue will highlight the preventive and therapeutic potential of physical activity and exercise in improving individual and public health outcomes.

This Special Issue aims to continue showing the role of physical activity and exercise in promoting well-being, managing chronic conditions, and preventing disease through high-quality research and clinical studies that explore exercise-based, innovative, evidence-based approaches to health control. The goal is to bring together interdisciplinary perspectives that advance the understanding of the preventive and therapeutic potential of physical activity.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  1. Effects of physical activity and exercise on different health dimensions (e.g., musculoskeletal, cardiovascular, ocular, metabolic, psychological).
  2. Influence of exercise-based interventions on body composition and functionality (including perceptual mechanisms, balance, strength, and other parameters).
  3. Measurement and quantification of exercise for health.
  4. Healthy aging through exercise.

We look forward to receiving your contributions.

Dr. Javier Gene-Morales
Guest Editor

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Keywords

  • physical activity
  • exercise-based interventions
  • chronic disease prevention
  • health promotion
  • cardiovascular health
  • ocular health
  • mental well-being
  • metabolic function
  • lifestyle interventions
  • public health outcomes

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Published Papers (1 paper)

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Research

28 pages, 3802 KiB  
Article
Effects of High-Resistance Elastic Band Training and a Curcumin-Based Formulation on Neuro-Oxidative and Functional Health in Sedentary Older Adults
by Alvaro Juesas, Angel Saez-Berlanga, Javier Gene-Morales, Pablo Jiménez-Martínez, Carlos Alix-Fages, Julio Fernandez-Garrido, Oscar Caballero, Danica Janicijevic, Virginia Zarza and Juan C. Colado
Healthcare 2025, 13(9), 1055; https://doi.org/10.3390/healthcare13091055 - 3 May 2025
Viewed by 146
Abstract
Background/Objectives: Physical exercise and curcumin supplementation can positively influence parameters related to cognition and neuro-oxidative status. However, research on the combined effects of resistance training with elastic bands and supplementation with a curcumin-based formulation is limited. Moreover, different types of contractions (e.g., [...] Read more.
Background/Objectives: Physical exercise and curcumin supplementation can positively influence parameters related to cognition and neuro-oxidative status. However, research on the combined effects of resistance training with elastic bands and supplementation with a curcumin-based formulation is limited. Moreover, different types of contractions (e.g., concentric and eccentric) may elicit distinct neurophysiological effects. This study evaluated the effectiveness of two high-resistance training (high-RT) programs using elastic bands in improving neuro-oxidative markers (brain-derived neurotrophic factor [BDNF] and F2-isoprostanes), cognitive function, physical performance, and quality of life, and examined the additional benefits of curcumin supplementation. Methods: Eighty-one sedentary older adults were randomly assigned to one of the following groups: accentuated eccentric training with either a bio-optimized curcumin formulation (Aecc-Cur) or placebo (Aecc-Pla); maximum strength training with either curcumin (Max-Cur) or placebo (Max-Pla); or a control group receiving curcumin (C-Cur) or placebo (C-Pla) without training. The training groups participated in a 16-week full-body high-RT program using elastic bands. Results: BDNF significantly increased in Aecc-Cur and Aecc-Pla (both p ≤ 0.020) but showed no changes after Max-Cur or Max-Pla (both p ≥ 0.256). All other dependent variables improved similarly across training groups (all p ≤ 0.50). Curcumin supplementation combined with exercise significantly reduced F2-isoprostanes in the Max-Cur group compared to Aecc-Pla, and enhanced 6-Minute Walk Test performance in Aecc-Cur and Max-Cur compared to their placebo counterparts. C-Cur showed nonsignificant changes in BDNF, F2-isoprostanes, social functioning, and vitality, while C-Pla worsened these parameters. Notably, at least half of the participants in the experimental groups exhibited clinically significant improvements in 11 of 14 dependent variables. Conclusions: Both high-RT protocols led to improvements in almost all dependent variables, with the Aecc program demonstrating greater effectiveness in boosting BDNF, a key neuroprotection marker. Curcumin supplementation alone and with exercise positively influenced neuro-oxidative markers and quality of life. Full article
(This article belongs to the Special Issue Innovative Exercise-Based Approaches for Chronic Condition Management)
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