Genetic Insights into Aging and Age-Related Diseases
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 36
Special Issue Editor
Interests: somatic mutations; genomic instability; neurodegeneration; aging; genetics; genomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The progression of aging is determined by complex multifactorial interactions. Genetics and epigenetics are important contributors, as they can be directly related to the hallmarks of aging: genome instability, telomere attrition, epigenetic alteration, and mitochondrial dysfunction. These genetic and epigenetic abnormalities also contribute to the susceptibility to neurodegeneration, cancer, and other age-related diseases by mechanisms that are poorly understood. Understanding the mechanisms by which genetics combines with environmental factors to lead to disease or health is a critical gap in our knowledge that needs to be addressed in order to develop preventive and therapeutic interventions and promote successful aging. This Special Issue will focus on research that reveals the details of how genetic and epigenetic factors increase the susceptibility to/or protect against age-related diseases.
Dr. Monica Sanchez-Contreras
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- somatic mutations
- aging
- genomic instability
- DNA damage
- neurodegeneration
- cancer
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