Multi-Omics, Bioinformatics & Cancers
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Bioinformatics".
Deadline for manuscript submissions: closed (15 June 2024) | Viewed by 291
Special Issue Editor
Interests: tumor microenvironment; cancer immunology; immune checkpoint blockade; single-cell spatial analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Tumors showcase a wide range of genetic changes influencing their initiation, growth, and progression, with these mutations granting advantages leading to immune evasion and therapy resistance. The tumor microenvironment significantly shapes interactions between tumor cells and the immune system, impacting treatment outcomes.
Understanding how specific tumor mutations contribute to immune evasion is crucial for effective immunotherapies. Certain oncogenic mutations can generate neoantigens, eliciting an immune response. However, tumor cells employ various mechanisms to escape immune surveillance. Investigating the interplay between tumor mutations and immune evasion mechanisms reveals insights into treatment resistance.
Targeted therapies have transformed cancer treatment, inhibiting key signaling pathways. Yet, resistance, often involving immune evasion mechanisms, poses a challenge. Exploring the crosstalk between immune evasion and targeted therapy resistance unveils complex adaptive responses, guiding the development of combination strategies.
This Special Issue delves into cutting-edge research, exploring therapeutic approaches that exploit the interplay between tumor mutations, immune evasion, and targeted therapy resistance using bioinformatics and multi-omics approaches. We welcome diverse contributions, including those investigating tumor mutational processes' impact on immune recognition, overcoming therapy resistance, and therapeutic modulation of the tumor immune microenvironment.
Dr. Shanye Yin
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer genetics
- bioinformatics
- multi-omics
- drug resistance
- immune
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
