Minimally Invasive Surgery for Upper Gastrointestinal Tract Diseases: New Trends and Future Perspectives

A special issue of Gastrointestinal Disorders (ISSN 2624-5647).

Deadline for manuscript submissions: 31 October 2026 | Viewed by 545

Special Issue Editor


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Guest Editor
Department of Clinical Medicine and Surgery, 'Federico II' University of Naples, Via Pansini 5, 80131 Naples, Italy
Interests: mininvasive surgery; robotic surgery; laparoscopic surgery; upper GI surgery; lower GI surgery

Special Issue Information

Dear Colleagues,

Over the past few decades, minimally invasive surgery (MIS) has revolutionized the management of upper gastrointestinal (UGI) tract diseases, providing significant advantages in terms of postoperative recovery, morbidity reduction, and quality of life. Continuous technological progress, with laparoscopic surgery first and then robotic surgery, has allowed for increasingly precise and personalized treatment of benign and malignant diseases of the UGI tract.

This Special Issue aims to provide an updated and comprehensive overview of recent developments and future perspectives in MIS for UGI diseases. Benign conditions such as gastroesophageal reflux disease (GERD) and achalasia have greatly benefited from minimally invasive and endoscopic approaches, which offer durable results with reduced invasiveness. Similarly, the application of MIS in the treatment of esophageal and gastric malignancies has expanded, supported by advances in instrumentation, imaging, and perioperative care. Emerging technologies such as artificial intelligence (AI) and indocyanine green (ICG) fluorescence imaging are further enhancing the capabilities of modern surgery. AI-assisted systems have the potential to improve diagnostic accuracy, optimize intraoperative decision-making, and refine surgical training through real-time data analysis and predictive modeling. Meanwhile, ICG fluorescence has proven valuable in intraoperative visualization, perfusion assessment, and lymphatic mapping, thereby increasing the precision and safety of complex procedures.

We invite submissions of original research articles, clinical studies, systematic reviews, and technical notes addressing, but not limited to, the following topics:

  • Minimally invasive and robotic techniques for benign and malignant UGI diseases;
  • Clinical and functional outcomes after minimally invasive esophagectomy and gastrectomy;
  • Integration of AI in preoperative planning and intraoperative guidance;
  • Role of ICG fluorescence imaging in oncologic and functional UGI surgery.

By gathering contributions from surgeons, endoscopists, and researchers in related disciplines, this Special Issue seeks to promote a multidisciplinary discussion on the current state and future directions of MIS for UGI diseases, fostering scientific exchange and improving patient care through technological and procedural innovation.

Dr. Giuseppe Palomba
Guest Editor

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Keywords

  • robotic surgery
  • laparoscopic surgery
  • esophageal surgery
  • gastroesophageal reflux disease (GERD)
  • achalasia
  • esophageal cancer
  • gastric cancer
  • artificial intelligence (AI)
  • indocyanine green (ICG) fluorescence

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Published Papers (1 paper)

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Review

15 pages, 748 KB  
Review
Minimally Invasive Pancreas-Preserving Duodenal Resections: Indications, Technical Strategies, and Outcomes
by Mario Annecchiarico, Giuseppe Loiaco, Claudia Cirillo, Antonio Antonino, Giulio Argenio, Angela Romano, Antonio Varricchio, Francesco Carafa, Pellegrino Gambardella, Giovanni Aprea and Giuseppe Palomba
Gastrointest. Disord. 2026, 8(2), 25; https://doi.org/10.3390/gidisord8020025 - 18 May 2026
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Abstract
Minimally invasive pancreas-preserving duodenal resection (MIPPDR) encompasses laparoscopic, robotic, and intentionally hybrid duodenal resections performed without pancreatic parenchymal excision, ranging from transduodenal local excision or ampullectomy to sleeve, segmental, subtotal, near-total, and total duodenectomy. This targeted narrative review was designed to provide a [...] Read more.
Minimally invasive pancreas-preserving duodenal resection (MIPPDR) encompasses laparoscopic, robotic, and intentionally hybrid duodenal resections performed without pancreatic parenchymal excision, ranging from transduodenal local excision or ampullectomy to sleeve, segmental, subtotal, near-total, and total duodenectomy. This targeted narrative review was designed to provide a clinically oriented synthesis of the available literature on indications, operative strategies, platform selection, reconstruction, perioperative outcomes, oncological adequacy, and functional considerations. A structured literature search was performed in PubMed/MEDLINE, Scopus, and Web of Science up to March 2026. The review focused on minimally invasive or intentionally hybrid pancreas-preserving duodenal resections reporting operative technique, perioperative outcomes, oncological outcomes, or functional sequelae. The minimally invasive literature consisted predominantly of case reports, technical notes, video articles, and small retrospective series, with substantial heterogeneity in lesion type, anatomical location, procedure extent, reconstruction, and outcome reporting. Laparoscopy appeared most reproducible for distal, infra-papillary, and limited resections with relatively low reconstructive burden, whereas robotics appeared to offer specific technical advantages for periampullary dissection, ductal identification, and intracorporeal reconstruction. However, the available evidence was insufficient to define firm comparative indications between platforms or to demonstrate superiority of one minimally invasive approach over another. Functional outcomes, despite their central relevance to the rationale of pancreas preservation, were poorly standardized and inconsistently reported. MIPPDR was therefore interpreted as a selective pancreas-preserving strategy positioned between advanced endoscopic therapy and pancreaticoduodenectomy. Future studies should adopt anatomy-based reporting, distinguish ampullary, periampullary, and distal duodenal disease, and include standardized functional endpoints. Full article
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