Molecular Targets of Colorectal Cancer Chemoprevention
A special issue of Gastrointestinal Disorders (ISSN 2624-5647).
Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 504
Special Issue Editor
Special Issue Information
Dear Colleagues,
According to the International Agency for Research on Cancer, colorectal cancer (CRC) was the third most commonly diagnosed cancer, with 2 million new cases in 2020 across the globe. At the same time, CRC was second on the list of most common cancer-related deaths worldwide, causing almost 1 million deaths. Although the trends of CRC incidences are either slightly decreasing or not changing in adults 50 and above, there is an increased incidence of young-onset (in ages <50 years) CRC in many parts of the world. While the medical field is responding to this issue by focusing on early detection by offering more screening at an earlier age to curb this increase in the young onset of CRC, we still do not know exactly what the main underlying mechanisms and molecular characterization of these cancers are.
The main aim of this Special Issue is to highlight some of the relevant ongoing efforts in the field of CRC chemoprevention with a focus on molecular profiling using multi-omics-based approaches; i.e., proteomics, proteogenomics, and RNA sequencing. This may help us to offer more premises to make progress in the molecularly directed chemoprevention of CRC.
We encourage authors to submit their original research (preclinical or clinical) or provide their current review and opinion in the “Molecular Targets of Colorectal Cancer Chemoprevention” Special Issue.
Dr. Muhammad Nadeem Aslam
Guest Editor
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Keywords
- colon cancer
- early onset
- chemoprevention
- cancer prevention
- calcium sensing receptor
- molecular targets
- proteomics
- proteogenomics
- RNA sequencing
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