Antiviral Drug Discovery and Development: Current Innovations and Future Trends
A special issue of Future Pharmacology (ISSN 2673-9879).
Deadline for manuscript submissions: 31 May 2024 | Viewed by 586
Special Issue Editor
Interests: antiviral drug; medicinal chemistry; drug design; new drug modalities
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Infections caused by viruses have been a prominent factor contributing to human mortality since ancient times. Despite the escalating number of antiviral medications approved for clinical use, prolonged usage can readily result in the emergence of drug resistance and adverse effects. The discovery of safe and efficacious antiviral medications is therefore pivotal in the management of viral infections.
Viral infections pose a significant threat to human health. For medicinal chemists, the research and development of antiviral drugs should not only focus on current chronic viral infections such as AIDS and hepatitis B, which are challenging to cure, but should also adopt a strategic vision by targeting potential future virus outbreaks and developing broad-spectrum antiviral drugs. This critical situation necessitates the proficient utilization of classical medicinal strategies for antiviral drug development, and the simultaneously fostering of innovative research paradigms in order to greatly enhance the success rate of such endeavors. This Special Issue warmly welcomes novel research in the field of antiviral drugs.
In this Special Issue, original research articles and reviews are welcome.
Prof. Dr. Peng Zhan
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Future Pharmacology is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antiviral drug discovery
- rational drug design
- phenotypic screening
- structure optimization
- structure–activity relationship
- structural biology
- molecular simulation
- virtual screening
- chemical synthesis
- combinatorial chemistry
- computational chemistry
- molecular hybridization
- scaffold hopping
- bioisosterism
- prodrug
- mechanic-based drug design
- transition state theory
- targeted covalent inhibitors
- substrate envelope
- high-throughput synthesis
- high-throughput protein crystallography
- parallel medicinal chemistry
- spatial-patterned interaction
- multivalent interaction
- molecular tongs
- molecular tweezers
- geometry-matching topography
- membrane-disrupting molecules
- supramolecular drug
- proximity-induced nucleic acid degrader
- proteolysis targeting chimera
- proximity-mediated effects
- sequence-based design
- sub-stoichiometric modulation
- artificial intelligence
- drug resistance
