What Is Your Diagnosis?—Case Report Collection

A special issue of Dermato (ISSN 2673-6179).

Deadline for manuscript submissions: 30 June 2025 | Viewed by 6725

Special Issue Editors


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Guest Editor
Centro Hospitalar Universitário São João, Porto, Portugal
Interests: oncobiology; urogenital tumors; cutaneous solid tumors; soft tissue & bone tumors; CNS tumors; neuroendocrine tumors

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Guest Editor
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
Interests: cutaneous lymphoma; psoriasis; genomics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Case Report Special Issue calls for perceptions of established or new standpoints concerning dermatology entities. It aims to include articles addressing case reports relevant to clinical dermatology practice and provide an evidence-based, balanced, pathology-oriented review of a clinical pathology topic. The topic should be restricted to a single defined diagnostic entity.

Dr. Jose Manuel Lopes
Prof. Dr. Robert Gniadecki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dermato is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diagnosis
  • treatment
  • toxicities of therapy
  • advances in diagnosis and treatment

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Published Papers (3 papers)

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7 pages, 3846 KiB  
Case Report
Rare Presentation, Critical Diagnosis: Primary Actinomycosis of the Foot
by Alexandra Maria Dorobanțu, Mihai Lupu, Liliana Gabriela Popa, Raluca Tatar, Calin Giurcaneanu, Irina Tudose and Olguta Anca Orzan
Dermato 2024, 4(3), 72-78; https://doi.org/10.3390/dermato4030008 - 4 Jul 2024
Cited by 1 | Viewed by 1483
Abstract
Actinomycosis, an uncommon granulomatous infection caused by the Actinomyces species, rarely targets as primary involvement the limb and is often linked to traumatic incidents. In this report, we present the case of a 44-year-old female who developed multiple small nodules on her left [...] Read more.
Actinomycosis, an uncommon granulomatous infection caused by the Actinomyces species, rarely targets as primary involvement the limb and is often linked to traumatic incidents. In this report, we present the case of a 44-year-old female who developed multiple small nodules on her left foot over approximately 12 months. Some nodules exhibited firmness and a violet hue, while others discharged a yellowish fluid. The patient had no significant comorbidities. Despite thorough blood paraclinical assessments, including complete blood count, serological HIV testing, and QuantiFERON-TB Gold testing, no abnormalities were detected. Bacteriological examinations and cultures of the discharge yielded negative results. Dermatoscopic examination revealed ovoid yellowish structures, with confocal microscopy highlighting granulomas. A subsequent skin biopsy confirmed characteristic changes indicative of actinomycosis. Although systemic antibiotic therapy with penicillin derivatives was initially considered, the patient’s documented allergic history to this medication class, verified through allergological testing, prompted the initiation of doxycycline treatment. Notably, significant improvement was observed at the 3-month follow-up. This case underscores the importance of reporting rare instances of actinomycosis due to its diagnostic complexity and management challenges. Full article
(This article belongs to the Special Issue What Is Your Diagnosis?—Case Report Collection)
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12 pages, 10698 KiB  
Case Report
The Transition from Pemphigus Foliaceus to Pemphigus Vegetans—An Intriguing Phenomenon within the Spectrum of Autoimmune Blistering Diseases: A Case Report
by Olguța Anca Orzan, Liliana Gabriela Popa, Iulia Badiu, Ana Ion, Călin Giurcăneanu, Beatrice Bălăceanu-Gurău and Irina Tudose
Dermato 2024, 4(2), 60-71; https://doi.org/10.3390/dermato4020007 - 14 Jun 2024
Viewed by 2419
Abstract
Pemphigus vegetans and pemphigus foliaceus are rare autoimmune blistering diseases characterized by the disruption of desmosomal adhesion proteins, particularly desmoglein 3 and desmoglein 1. We report the case of a 62-year-old male who presented initially with scaly red plaques posing several diagnostic challenges. [...] Read more.
Pemphigus vegetans and pemphigus foliaceus are rare autoimmune blistering diseases characterized by the disruption of desmosomal adhesion proteins, particularly desmoglein 3 and desmoglein 1. We report the case of a 62-year-old male who presented initially with scaly red plaques posing several diagnostic challenges. A histopathological examination revealed subcorneal acantholysis, matching the suspected clinical diagnosis of pemphigus foliaceus. The patient progressed, developing vegetating plaques, and a new biopsy was performed. The new histopathological and direct immunofluorescence exams were consistent with pemphigus vegetans. This case highlights the diagnostic challenges posed by the transition of pemphigus foliaceus to its vegetating form. We discuss the role of desmogleins in the pathogenesis of pemphigus and explore potential therapeutic strategies targeting these specific autoantigens. Full article
(This article belongs to the Special Issue What Is Your Diagnosis?—Case Report Collection)
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4 pages, 1161 KiB  
Case Report
Adenosquamous Carcinoma of the Skin: A Case Report
by Rim Jridi, Franziska Hartmann, Stefanie Boms, Andrea Tannapfel and Thilo Gambichler
Dermato 2023, 3(4), 263-266; https://doi.org/10.3390/dermato3040020 - 13 Dec 2023
Viewed by 2095
Abstract
Adenosquamous carcinoma of the skin (ASCS) or primary cutaneous adenosquamous carcinoma is a rare malignant neoplasm. It is characterized by the presence of both glandular and squamous cell components and a propensity for aggressive clinical behavior. Due to its rarity, it continues to [...] Read more.
Adenosquamous carcinoma of the skin (ASCS) or primary cutaneous adenosquamous carcinoma is a rare malignant neoplasm. It is characterized by the presence of both glandular and squamous cell components and a propensity for aggressive clinical behavior. Due to its rarity, it continues to pose diagnostic challenges. To date, only a few cases of this tumor have been reported, and even fewer have been thoroughly investigated via immunohistochemistry. Full article
(This article belongs to the Special Issue What Is Your Diagnosis?—Case Report Collection)
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