Characterization of Bio-Molecular Crystals from the Classic to Modern Methods
A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 202
Special Issue Information
Dear Colleagues,
Nowadays, new technologies have allowed scientists to look at the molecular structure of small molecules at very high resolution. The situation is very promising in the case of biomolecular crystals (proteins, membrane proteins, nucleic acids, polysaccharides, and their complexes). High-resolution structures need to include modern methods like robotics for the obtainment of crystals up to using synchrotron facilities, where microcrystals in the size of microns are feasible to be diffracted. There are other techniques like nuclear magnetic resonance (NMR) to obtain the structure in solution or modern cryo-electron microscopy, which allow one to obtain the 3D structure of huge macromolecular complexes. Some methods like chemical modelling also allow one to predict the 3D structure with high reliability; additionally, the modern serial crystallography via X-ray free electron lasers is a promising method to obtain the 3D structures in a short time. This Special Issue will focus on technical and theoretical aspects related to the characterization of biomacromolecular samples, either in solution or in a solid state, or in a gas state. All papers focused on methods should include an overview or a description of the methods and an experimental case study as application. The experimental setup will be also reviewed. We encourage all scientists to submit contributions to this Special Issue. We will be delighted to see your contribution to Crystals.
Sincerely yours,
Dr. Vivian Stojanoff
Prof. Dr. Abel Moreno
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Systems: biological macromolecules, protein crystals; biocrystals; crystal growth; protein crystallography; crystal chemistry; biomineralization; biomimetics;
- Methods: X-ray methods for structure molecular determination (powder diffraction, small molecule, macromolecular crystallography, solution scattering); cryo-EM; NMR; mass spectroscopy; etc.
