Atomic-Resolution Crystallography of Biomolecules
A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".
Deadline for manuscript submissions: closed (31 October 2020) | Viewed by 306
Special Issue Editor
2. Biocenter Oulu, University of Oulu, 90014 Oulu, Finland
Interests: membrane proteins; structural biology; protein crystallography; cryo-EM; structural neurobiology; myelin; structural basis of disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Structural biology is the key to understanding the function of biological macromolecules. Significant state-of-the-art developments in recent years have brought about novel methods to decipher structures of biomolecules, most importantly cryo-EM, SAXS, and XFEL techniques. In addition, improvements in computing power and algorithms are bringing computer simulations closer to biologically important timescales. However, in the midst of these exciting developments, atomic-resolution crystallography remains an important and central tool in understanding fine details of macromolecular structure and function.
The purpose of this Special Issue is to collect current views and recent results on various aspects of (sub)atomic-resolution crystallography of biomolecules. The topics include, but are not limited to, the following:
- the benefits of ultrahigh-resolution crystallography;
- results from atomic-resolution studies of biomolecules;
- methods for crystallisation for such studies;
- technical aspects of data collection and processing; and
- refinement and validation of ultrahigh-resolution biomolecular structures.
Prof. Dr. Petri Kursula
Dr. Salla Ruskamo
Guest Editors
Manuscript Submission Information
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Keywords
- macromolecular crystallography
- biomolecular crystallization
- data collection
- data processing
- structure refinement and validation
- atomic resolution
- proteins and nucleic acids
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