Advances in Bifunctional Organocatalysis
A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Catalysis in Organic and Polymer Chemistry".
Deadline for manuscript submissions: closed (10 October 2021) | Viewed by 417
Special Issue Editor
Interests: organocatalysis; bifunctional; asymmetric synthesis; hydrogen-bond; enantioselective; thiourea; squaramide; cinchona alkaloid
Special Issue Information
Dear Colleagues,
Since the initial introduction of organocatalysis, defined in 2000 as the use of molecules of low molecular weight to perform organic reactions, it has become an important alternative to asymmetric synthesis. Its power as a synthetic tool is emphasized by the large number of new reactions and activation modes described in the literature during the last couple of decades. Nowadays, organocatalysis represents an important option since it also presents the possibility of carrying out cascade reactions, allowing the construction of enantiopure, sophisticated targets in a single operation with the use of a single catalyst; it also represents a key step in the synthesis of intermediates of different natural products and biologically active compounds. The use of catalysts based on non-covalent interactions has been explored as an alternative methodology for the catalytic activation of a wide variety of substrates with different natures. Among them, bifunctional catalysts that can promote enantioselective processes through hydrogen-bonding have been widely explored in recent decades. These catalysts, based on a hydrogen bond donor core (mainly thiourea or squaramide) decorated with a second functionality, allow the synergistic activation of both coupling partners involved in the reaction, giving access to products that are otherwise difficult to synthesize. The secondary functionality has been particularly modified in recent years in order to develop new organocatalysts able to activate substrates of different natures. Therefore, recently, bifunctional organocatalysts have been widely employed in the literature, making this family of catalysts a powerful tool in asymmetric synthesis, with further potential yet to be exploited.
Dr. Jose A. Fernandez-Salas
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Organocatalysis
- bifunctional
- asymmetric synthesis
- hydrogen-bond
- enantioselective
- thiourea
- squaramide
- cinchona alkaloid
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
