Molecular Genomics of Oral Submucous Fibrosis Pathology

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 579

Special Issue Editor


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Guest Editor
National Institutes of Health (NIH), Bethesda, MD 20892, USA
Interests: cancer; biomarker; genetics; gene expression; RNAseq; scRNAseq; epigenetics; ChIPseq immunology

Special Issue Information

Dear Colleagues,
Oral Submucous Fibrosis (OSF) is primarily characterized by the accumulation and increased deposition of collagen in oral submucosal tissue, which leads to several downstream changes in the associated tissues. Various factors contribute to these fibrous and associated changes, which include, but are not limited to, the activation of fibroblasts and chronic inflammation induced by transforming growth factor-beta (TGF-β) and other key cytokines. Recent advances in various sequencing techniques have identified novel molecular pathways associated with the pathogenesis of OSF. Novel biomarkers of OSF have been identified, and newer therapeutic strategies are paving the way for significant advances in the management of OSF.

In this upcoming Special Issue, we aim to bring together cutting-edge research dedicated to enhancing our understanding of the molecular pathogenesis and the epigenetic landscape of OSF, including gene expression, therapeutic strategies, the functional implication of polymorphisms, and pathogenesis.

We are excited to invite you to contribute scientific articles for the upcoming Special Issue of Biomedicines. We encourage submission under the categories of original research articles, reviews, and perspectives. Your contributions will significantly contribute to the growing body of knowledge in this field.

Key themes for submissions include, but are not limited to, the following:

  1. Molecular basis of and signaling pathways in OSF.
  2. Gene expression patterns using advanced sequencing technologies in OSF.
  3. Immune biomarkers of OSF.
  4. Epigenetic landscape of OSF.
  5. Biomarkers and therapeutic approaches for managing OSF and improving patient outcomes.
  6. Clinical applications of novel research.

Submission guidelines and further details can be found on our website. We look forward to receiving your insightful contributions and working towards the collective progress in unraveling the complexities of Oral Submucous Fibrosis.

Dr. Sanjit Mukherjee
Guest Editor

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Keywords

  • oral submucous fibrosis
  • gene expression
  • biomarker
  • DNA methylation
  • epigenetic drugs
  • immune biomarkers
  • pathology
  • therapeutic interventions
  • epithelial mesenchymal transition
  • cancer stem cell marker

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Published Papers

This special issue is now open for submission.
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