Risk of Cardiovascular Disease and Cancer: Identification of Shared Disease Pathways
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 415
Special Issue Editor
Interests: cancer prevention; presurgical / Window of Opportunity (WOP) trials; phytochemicals in cancer prevention; drug repurposing in cancer prevention; risk biomarkers; breast intraepithelial neoplasia management
Special Issue Information
Dear Collogues,
Cardiovascular disease (CVD) and cancer are major causes of death worldwide, and strategies aimed at improving their treatment and prevention are global priorities. While they are distinct diseases, they share many similarities. The evidence suggests that modifiable risk factors, including diet, a sedentary lifestyle, obesity, and tobacco use, are critical to the pathogenesis of both diseases and reflect common genetic, cellular, and signaling mechanisms. Identifying new therapeutic and preventive strategies for both disorders is dependent on understanding this important biological overlap. Additionally, genetic and environmental interactions add to both diseases' complexity and will be the key to future research.
There is no doubt that multifaceted interventions are needed to address these issues, including behavioral and policy strategies as well as novel pharmacologic approaches. The most powerful strategy for preventing both cancer and CVD may be to modify common risk factors and target common disease pathways. In this Special Issue, we aim to publish original articles and/or reviews discussing the genetic and molecular factors that contribute to CVD and cancer, and how the strategies typically used for the prevention of atherosclerosis can be applied to cancer prevention.
Dr. Matteo Lazzeroni
Guest Editor
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