Hepatocellular Carcinoma: From Genomic and Epigenomic Regulation to Drug Discovery

Dear Colleagues,

Hepatocellular carcinoma (HCC) is one of the most common types of liver cancer and is responsible for a significant proportion of cancer-related deaths worldwide. Understanding the molecular mechanisms underlying HCC development and progression is crucial for the development of new diagnostic and therapeutic strategies. This Special Issue aims to gather original research articles, reviews, and perspectives related to the genomic and epigenomic regulation of HCC, including the identification of the key molecular mechanisms involved in the pathogenesis and progression of HCC. Furthermore, the Special Issue will also highlight the current state of the art in drug discovery for HCC, including novel targeted therapies and immunotherapies.

Potential topics of interest include, but are not limited to:

• Genomic and epigenomic profiling of HCC;
• Molecular mechanisms involved in HCC pathogenesis and progression;
• Biomarkers for early detection and prognosis of HCC;
• Targeted therapies for HCC;
• Immunotherapies for HCC;
• Drug-resistance mechanisms in HCC;
• Preclinical and clinical studies of HCC therapeutics

The goal of this Special Issue is to provide a comprehensive overview of the latest advances in the field of HCC research, which will be of interest to researchers, clinicians, and drug developers working in this area.

Dr. Feiyu Chen
Dr. Zhangfeng Zhong
Guest Editors

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