HBV Infection: From Host and Cellular Entry to Viral Persistence
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Microbiology in Human Health and Disease".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 129
Special Issue Editors
Interests: Viral hepatitis; Hepatitis B virus; HBV cellular entry; reporter viruses; CRISPR/Cas editing; reporter proteins; molecular cloning strategies
Interests: viral hepatitis; Hepatitis B virus; HBV cellular entry; lipoprotein/lipid transport and metabolism; neutral lipids (e.g., triglycerides and cholesterolesters); hepatotropic viruses
Special Issue Information
Dear Colleagues,
According to the World Health Organization (WHO) estimation of 2019, 296 million people have been chronically infected with the Hepatitis B virus (HBV) and 820 000 deaths per year are either directly attributed to HBV infection or associated diseases. Due to this high medical relevance, the WHO has proclaimed the elimination of viral hepatitis by 2030. However, although important improvements in HBV therapies have been achieved, there is no reliable cure for chronic HBV infection available to date.
This Special Issue aims to focus on the complete HBV infection cycle, beginning with the virus entry into the host, subsequent virus targeting of the liver, towards viral entry into the host cell and, finally, viral persistence, including cccDNA formation and viral genome integration. Here, we call for articles on clinical studies, case reports and research articles focusing on the discovery of new mechanisms and factors which complete our understanding of the many steps still unresolved HBV infection cycle.
Dr. Jochen M. Wettengel
Dr. Knud Esser
Guest Editors
Manuscript Submission Information
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Keywords
- hepatitis b virus (hbv)
- hbv infection
- hbv replication cycle
- hbv attachment and entry
- hbv liver targeting
- hbv host entry
- hbv cellular entry
- hbv cccdna formation
- hbv cccdna persistence
- hbv genome integration
- hbv novel strategies
- hbv cure