Genetic and Molecular Mechanisms of Cardiometabolic Diseases and Cancers—2nd Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular Genetics and Genetic Diseases".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 1042
Special Issue Editors
Interests: genetic epidemiology; cardiometabolic disease
Special Issues, Collections and Topics in MDPI journals
Interests: molecular epidemiology of chronic diseases; data mining
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiometabolic diseases (CMDs) and cancers, the two most prevalent non-communicable diseases globally, constitute major concerns worldwide. Recent evidence suggests close co-morbid linkages and shared risk factors between CMDs and cancers, calling for an integrated and systematic interrogation into their intercorrelation. Nevertheless, the mechanisms whereby genetic and other factors contribute to their co-occurrence remain unclear. Further research is therefore expected to provide novel insights into the genetic and molecular mechanisms underlying their correlations. Possible perspectives may involve shared genetic factors like genetic pleiotropy. In addition, complex interactions between genes and the environment, such as inter-generational genetic and environment transmission and interacting phenotypes influenced by genotypes, as well as their effects on the differentiated co-morbidity risks, require more comprehensive assessment.
In this Special Issue, we intend to take CMDs and cancers as examples to elucidate the intricate interconnections among complex diseases, and we welcome the submission of original high-quality research and review articles focused on (1) disease comorbidities; (2) genetic pleiotropy and heterogeneity; (3) genetic overlap and causality between CMD and cancers; and (4) indirect genetic effects.
Prof. Dr. Tao Wu
Prof. Dr. Dafang Chen
Guest Editors
Manuscript Submission Information
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Keywords
- cardiometabolic disease
- oncology
- comorbidity
- genetic pleiotropy
- direct genetic effects
- indirect genetic effects
- parent-of-origin
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