Emerging Molecular and Translational Insights into Obstructive Sleep Apnea and Its Cardiovascular Comorbidities
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: 30 June 2026
Special Issue Editors
2. School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung 804201, Taiwan
Interests: intensive care medicine; emergency medicine; general medicine
Interests: atrial fibrillation; electrophysiology; cardiac remodeling; biomarkers; sleep-disordered breathing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Obstructive Sleep Apnea (OSA) is increasingly being recognized as a systemic disorder associated with cardiovascular, metabolic, and neurocognitive consequences. Among these, its close relationship with atrial fibrillation (AF) and other cardiac arrhythmias highlights the interplay between sleep physiology, autonomic regulation, and molecular remodeling.
This Special Issue aims to showcase recent advances regarding the pathophysiological mechanisms, diagnostic innovations, and therapeutic strategies of OSA and its cardiovascular comorbidities. Topics include molecular mechanisms, epigenetic and transcriptomic regulation, biomarkers, inflammation, oxidative stress, and endothelial dysfunction. We particularly welcome studies exploring translational applications of omics, artificial intelligence, and precision medicine to improve OSA diagnosis, risk stratification, and treatment outcomes. Multidisciplinary research that bridges molecular biology, clinical practice, and digital innovation is encouraged.
Dr. Hui-Ting Wang
Dr. Yunglung Chen
Guest Editors
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Keywords
- obstructive sleep apnea (OSA)
- atrial fibrillation (AF)
- molecular mechanisms
- epigenetics
- biomarkers
- oxidative stress
- inflammation
- endothelial dysfunction
- translational research
- precision medicine
- artificial intelligence
- cardiovascular comorbidities
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