Bacterial Infections, Oxidative Stress, and Inflammation: Integrative Therapeutic Solutions
Special Issue Editors
Interests: medicinal plants and natural products; free radicals and oxidative stress; animal models; inflammation and inflammatory diseases
Special Issues, Collections and Topics in MDPI journals
Interests: microbiology; bioremediation; yeast; chemistry; engineering
Interests: hydrogels; nanotechnology; controlled drug delivery; polymer materials; nanocellulose; biodegradable polymers; natural polymers; materials characterization; inflammation; antioxidants; natural compounds;
Special Issue Information
Bacterial infections remain a significant global health challenge, contributing to high morbidity and mortality rates. The interplay between bacterial pathogens and the host immune system often results in a cascade of molecular events characterized by oxidative stress and inflammation. These interconnected processes play critical roles in the progression of infectious diseases, influencing both acute and chronic outcomes.
Oxidative stress, driven by an imbalance between reactive oxygen species (ROS) and the antioxidant defense system, is a hallmark of bacterial infections. Excessive ROS production can damage cellular components, including lipids, proteins, and DNA, exacerbating tissue damage and promoting inflammatory pathways. In parallel, the host's inflammatory response, while essential for controlling bacterial proliferation, can become dysregulated, leading to chronic inflammation and tissue injury.
This Special Issue aims to explore the intricate relationship between bacterial infections, oxidative stress, and inflammation. We welcome original research articles, reviews, and case studies that focus on but are not limited to the following topics:
The molecular mechanisms of oxidative stress and inflammation during bacterial infections;
The role of bacterial virulence factors in modulating host oxidative and inflammatory responses;
Novel biomarkers for oxidative stress and inflammation in bacterial infections;
Antioxidant and anti-inflammatory therapeutic strategies to mitigate bacterial infection-induced damage;
Interactions between the microbiota, oxidative stress, and inflammation in health and disease;
Cutting-edge techniques for studying oxidative stress and inflammation in the context of bacterial infections.
This Special Issue aims to provide a comprehensive overview of the mechanisms and clinical implications of oxidative stress and inflammation in bacterial infections. It also aims to advance understanding in this field and present therapeutic strategies to combat bacterial infections and their associated oxidative and inflammatory pathologies. We welcome contributions from diverse disciplines, including microbiology, immunology, pharmacology, and clinical medicine, to foster interdisciplinary dialog and collaboration.
We look forward to receiving your valuable contributions.
Dr. Hicham Wahnou
Dr. Gustavo Fehrenbach
Dr. Tielidy Lima
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bacteria is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bacterial infections
- oxidative stress
- inflammation
- reactive oxygen species (ROS)
- antioxidants
- therapeutic strate-gies
- microbiota
- biomarkers, virulence factors
- nanoformulations
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