Chemical Composition and Toxicology of Indoor Particulate Matter

A special issue of Atmosphere (ISSN 2073-4433). This special issue belongs to the section "Air Quality and Human Health".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 3134

Special Issue Editors

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Guest Editor
Department of Chemistry and Applied Physics, University of León (Unileon), Campus de Vegazana, 24007 León, Spain
Interests: outdoor/indoor air quality; atmospheric aerosol; health effects

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Guest Editor
Centre for Environmental and Marine Studies (CESAM), Department of Environment and Planning (DAO), University of Aveiro (UA), 3810-193 Aveiro, Portugal
Interests: air quality; organic tracers; emissions; aerosols

Special Issue Information

Dear Colleagues,

Considering the current context of the COVID-19 pandemic, indoor air quality has become an increasingly important issue. Time spent indoors has increased due to lockdowns and remote working. In this new reality most of our exposure to particulate matter takes place indoors, where levels can far exceed those measured outdoors. Studies focusing on the detailed physicochemical characterization of particulate matter in indoor environments are of great interest due to their ability to trigger toxicological responses with impact on human health. The toxicological properties of the particulate matter to which we are exposed influence the cytotoxicity, genotoxicity, mutagenicity and potential to induce inflammation, constituting an issue of great concern in the scientific community.

Guest Editors invite you to consider submitting your research for publication in this Special Issue of Atmosphere focusing on “Chemical Composition and Toxicology of Indoor Particulate Matter”. The aim of this Special Issue is to communicate a selection of novel contributions in the form of critical reviews and research papers related to indoor air pollutants/quality and their toxicological effects. Potential authors are welcome to contact the Guest Editors with questions regarding their chosen topics for this Special Issue.

Dr. Cátia Gonçalves
Dr. Ana Margarida Vicente
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • particle chemical composition
  • indoor chemistry
  • toxicological assays
  • health effects
  • exposure
  • inhalable particulate matter

Published Papers (1 paper)

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14 pages, 1369 KiB  
Intrinsic Characteristics and Biological Effects of Standard Reference Indoor Dust SRM® 2585 and Its Inhalable Subfractions PM10 and PM2.5
by Carine El Hajjar, Tiphaine Rogez-Florent, Virginie Seguin, Anthony Verdin, David Garon, Ivannah Pottier and Véronique André
Atmosphere 2022, 13(11), 1818; - 01 Nov 2022
Cited by 1 | Viewed by 2644
Standard Reference Material® (SRM®) 2585 can be considered as a model sample of settled indoor dust. At least 168 adsorbed chemicals were identified and quantified, generating a complex and potentially toxic mixture. Inhalable fractions PM10 and PM2.5 were [...] Read more.
Standard Reference Material® (SRM®) 2585 can be considered as a model sample of settled indoor dust. At least 168 adsorbed chemicals were identified and quantified, generating a complex and potentially toxic mixture. Inhalable fractions PM10 and PM2.5 were isolated and compared to SRM® 2585 for their intrinsic properties and their respiratory toxicity using pertinent normal human bronchoepithelial (NHBE) cells. The intrinsic oxidative potential (OP) of SRM® 2585 and its subfractions was measured in acellular conditions, together with ROS generation and endotoxin content. For SRM® 2585 and PM10, cellular responses were evaluated on NHBE cells after 72 h exposure (1.1 to 110 µg/mL). The presence of endotoxins associated with an intrinsic prooxidant potential did not lead to the induction of an inflammatory response. Interestingly, cytokine production was decreased, strongly for IL-1β and to a lesser extent for IL-6. Only PM10 induced an acute toxicity. In parallel, mutagenicity was evaluated from organic extracts. Mutagenic profiles indicated the concomitant presence of nitro-PAHs in addition to the previously reported PAHs. This could be of concern for long-term health effects in a context of chronic exposure. Full article
(This article belongs to the Special Issue Chemical Composition and Toxicology of Indoor Particulate Matter)
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