Separation and Analysis of Circulating Markers in Liquid Biopsy

Dear Colleagues,

Liquid biopsy has emerged as a momentous technological breakthrough in medical sciences and engineering with significant potential for early disease detection, diagnosis, prognosis, therapeutic outcome prediction, and evaluation of recurrence or disease progression. Its minimally invasive examination allows for more frequent monitoring of patients at an affordable cost, with less pain and risk involved. It is also expected to bring substantial socioeconomic burden reduction to our society through this game-changing strategy. For these reasons, developing sensitive separation and in-depth analytical tools of circulating markers (CTCs, Exosomes, cfDNA, etc.) is urgently needed.

This Special Issue in Applied Sciences aims to feature recent advances and progresses in this field, specifically focusing on two main technologies, separation and analysis, toward liquid biopsy. As the key to liquid biopsy is isolating circulating markers from body fluids more sensitively and analyzing the isolated circulating markers more precisely, this Special Issue will allow many young researchers in this field to be inspired and get to know technical challenges in the field. Any manuscripts and extended versions of conference papers that cover novel ideas toward this field are welcome, and the inclusion of clinical implications with actual clinical specimens would be a plus.

Dr. Yoon-Tae Kang
Guest Editor

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• circulating markers
• separation and analysis
• liquid biopsy
• CTCs
• Exosomes
• cfDNA
• disease detection, diagnosis, and prognosis