Special Issue "Antibody Phage Display"
A special issue of Antibodies (ISSN 2073-4468).
Deadline for manuscript submissions: closed (1 May 2019)
Dr. Jamshid Tanha
Human Health Therapeutics Portfolio, National Research Council Canada, 100 Sussex Drive, Ottawa, Ontario, K1A 0R6, Canada
Website | E-Mail
Interests: Single domain antibody; Single domain antibody stability; Antibody phage and ribosome display technologies; Antibody affinity maturation; Antibody structure; Recombinant antibody/intrabody; Synthetic and natural antibody libraries; Microbiology
Despite the existence of several conceptually similar antibody discovery platforms, the antibody phage display library platform remains the most popular of all, mainly due to its robust nature, simplicity of use, and highly versatile nature with respect to the selection conditions. These factors, combined with the control over the direction of the selection the platform offers, allows for the efficient isolation of antibodies with the desired affinity, specificity, stability and function. Complementing the antibody phage display library platform with automation, next-generation sequencing or other antibody display platforms has further enhanced its capacity. Many of the antibody therapeutics approved or in development are obtained from phage display libraries including some blockbusters such as Humira and Lucentis.
This Special Issue will provide recent advances in aspects of antibody phage display libraries including antigen design, presentation and expression, immunization strategies and library design, construction, selection and screening that relate to the development of therapeutic and diagnostic antibodies.
Dr. Jamshid Tanha
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Antibody phage display libraries
- Therapeutic and diagnostic antibodies
- Antigen design, presentation and expression
- Immunization strategies
- Library design, construction, selection and screening