As all of the articles published in Cancers (ISSN: 2072-6694) are open access, you have free and unlimited access to the full text of all articles. We welcome you to read our most highly cited papers published in 2023 in the Section “Tumor Microenvironment”, which are listed below:

1. “5-Fluorouracil Suppresses Colon Tumor through Activating the p53-Fas Pathway to Sensitize Myeloid-Derived Suppressor Cells to FasL⁺ Cytotoxic T Lymphocyte Cytotoxicity”
by Yingcui Yang, Mingqing Zhang, Yongdan Zhang, Kebin Liu and Chunwan Lu
Cancers 2023, 15(5), 1563; https://doi.org/10.3390/cancers15051563
Available online: https://www.mdpi.com/2072-6694/15/5/1563

2. “Therapeutic Targeting of Cancer-Associated Fibroblasts in the Non-Small Cell Lung Cancer Tumor Microenvironment”
by Yasushi Shintani, Toru Kimura, Soichiro Funaki, Naoko Ose, Takashi Kanou and Eriko Fukui
Cancers 2023, 15(2), 335; https://doi.org/10.3390/cancers15020335
Available online: https://www.mdpi.com/2072-6694/15/2/335

3. “Significance of Cancer-Associated Fibroblasts in the Interactions of Cancer Cells with the Tumor Microenvironment of Heterogeneous Tumor Tissue”
by Yoshimi Arima, Satoko Matsueda and Hideyuki Saya
Cancers 2023, 15(9), 2536; https://doi.org/10.3390/cancers15092536
Available online: https://www.mdpi.com/2072-6694/15/9/2536

4. “Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1”
by Weili Tao, Ze Ouyang, Zhiqi Liao, Lu Li, Yujie Zhang, Jiali Gao, Li Ma and Shiying Yu
Cancers 2023, 15(8), 2378; https://doi.org/10.3390/cancers15082378
Available online: https://www.mdpi.com/2072-6694/15/8/2378

5. “Targeting Iron-Sulfur Clusters in Cancer: Opportunities and Challenges for Ferroptosis-Based Therapy”
by Jaewang Lee and Jong-Lyel Roh
Cancers 2023, 15(10), 2694; https://doi.org/10.3390/cancers15102694
Available online: https://www.mdpi.com/2072-6694/15/10/2694

6. “CD44 Intracellular Domain: A Long Tale of a Short Tail”
by Spyros S. Skandalis
Cancers 2023, 15(20), 5041; https://doi.org/10.3390/cancers15205041
Available online: https://www.mdpi.com/2072-6694/15/20/5041

7. “Modern Risk Stratification of Acute Myeloid Leukemia in 2023: Integrating Established and Emerging Prognostic Factors”
by Eleonora Boscaro, Irene Urbino, Federica Maria Catania, Giulia Arrigo, Carolina Secreto, Matteo Olivi, Stefano D’Ardia, Chiara Frairia, Valentina Giai, Roberto Freilone et al.
Cancers 2023, 15(13), 3512; https://doi.org/10.3390/cancers15133512
Available online: https://www.mdpi.com/2072-6694/15/13/3512

8. “Mycosis Fungoides and Sézary Syndrome: Microenvironment and Cancer Progression”
by Gabor Dobos, Ingrid Lazaridou and Adèle de Masson
Cancers 2023, 15(3), 746; https://doi.org/10.3390/cancers15030746
Available online: https://www.mdpi.com/2072-6694/15/3/746

9. “Efficient Brain Tumor Detection with Lightweight End-to-End Deep Learning Model”
by Mohamed Hammad, Mohammed ElAffendi, Abdelhamied A. Ateya and Ahmed A. Abd El-Latif
Cancers 2023, 15(10), 2837; https://doi.org/10.3390/cancers15102837
Available online: https://www.mdpi.com/2072-6694/15/10/2837

10. “Reshaping the Pancreatic Cancer Microenvironment at Different Stages with Chemotherapy”
by Maozhen Peng, Ying Ying, Zheng Zhang, Liang Liu and Wenquan Wang
Cancers 2023, 15(9), 2448; https://doi.org/10.3390/cancers15092448
Available online: https://www.mdpi.com/2072-6694/15/9/2448

11. “The Three-Dimensional In Vitro Cell Culture Models in the Study of Oral Cancer Immune Microenvironment”
by Elaheh Dalir Abdolahinia and Xiaozhe Han
Cancers 2023, 15(17), 4266; https://doi.org/10.3390/cancers15174266
Available online: https://www.mdpi.com/2072-6694/15/17/4266

12. “Highly Metastatic Subpopulation of TNBC Cells Has Limited Iron Metabolism and Is a Target of Iron Chelators”
by Yuze Wang, Toshiaki Ohara, Yuehua Chen, Yusuke Hamada, Chunning Li, Masayoshi Fujisawa, Teizo Yoshimura and Akihiro Matsukawa
Cancers 2023, 15(2), 468; https://doi.org/10.3390/cancers15020468
Available online: https://www.mdpi.com/2072-6694/15/2/468

13. “The Extracellular Matrix in Glioblastomas: A Glance at Its Structural Modifications in Shaping the Tumoral Microenvironment—A Systematic Review”
by Salvatore Marino, Grazia Menna, Rina Di Bonaventura, Lucia Lisi, Pierpaolo Mattogno, Federica Figà, Lal Bilgin, Quintino Giorgio D’Alessandris, Alessandro Olivi and Giuseppe Maria Della Pepa
Cancers 2023, 15(6), 1879; https://doi.org/10.3390/cancers15061879
Available online: https://www.mdpi.com/2072-6694/15/6/1879

14. “Immunotherapy for Colorectal Cancer with High Microsatellite Instability: The Ongoing Search for Biomarkers”
by Javier Ros, Iosune Baraibar, Nadia Saoudi, Marta Rodriguez, Francesc Salvà, Josep Tabernero and Elena Élez
Cancers 2023, 15(17), 4245; https://doi.org/10.3390/cancers15174245
Available online: https://www.mdpi.com/2072-6694/15/17/4245

15. “Important Cells and Factors from Tumor Microenvironment Participated in Perineural Invasion”
by Zirong Chen, Yan Fang and Weihong Jiang
Cancers 2023, 15(5), 1360; https://doi.org/10.3390/cancers15051360
Available online: https://www.mdpi.com/2072-6694/15/5/1360

You are invited to view and submit relevant papers to the journal Cancers.

Cancers Editorial Office