Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access journal dedicated to presenting the latest research findings in the field of clinical medicine and promoting knowledge exchange among medical researchers globally. We are delighted to share with you a selection of 2025 publications contributed by our Editorial Board Members. We extend our gratitude to all Editorial Board Members for their support and significant contributions. These selected papers have received many citations and cover nine sections of JCM, including (but not limited to) endocrinology and metabolism, mental health, cardiology, and clinical neurology. We welcome you to explore the full texts of these papers via the links below.

Further information about our Editorial Board Members can be found via https://www.mdpi.com/journal/jcm/editors.

Abstract submissions are also open for our online conference, the 4th International Online Conference on Clinical Medicine, chaired by our Editors-in-Chief, until 7 August 2026. To learn more, visit https://www.mdpi.com/journal/jcm/events.

1. “Muscle in Endocrinology: From Skeletal Muscle Hormone Regulation to Myokine Secretion and Its Implications in Endocrine–Metabolic Diseases”
   by Pedro Iglesias
   J. Clin. Med. 2025, 14(13), 4490; https://doi.org/10.3390/jcm14134490
   Full text available online: https://www.mdpi.com/2077-0383/14/13/4490
2. “Physician and Medical Student Burnout, a Narrative Literature Review: Challenges, Strategies, and a Call to Action”
   by Santiago Cotobal Rodeles, Francisco Javier Martín Sánchez and Manuel Martínez-Sellés
   J. Clin. Med. 2025, 14(7), 2263; https://doi.org/10.3390/jcm14072263
   Full text available online: https://www.mdpi.com/2077-0383/14/7/2263
3. “The Triad of Risk: Linking MASLD, Cardiovascular Disease and Type 2 Diabetes; From Pathophysiology to Treatment”
   by Eleni Michalopoulou, John Thymis, Stamatios Lampsas, George Pavlidis, Konstantinos Katogiannis, Dimitrios Vlachomitros, Eleni Katsanaki, Gavriella Kostelli, Sotirios Pililis, Loukia Pliouta et al.
   J. Clin. Med. 2025, 14(2), 428; https://doi.org/10.3390/jcm14020428
   Full text available online: https://www.mdpi.com/2077-0383/14/2/428
4. “The Role of NLRP3 Inflammasome in Type 2 Diabetes Mellitus and Its Macrovascular Complications”
   by Konstantinos Karamitsos, Evangelos Oikonomou, Panagiotis Theofilis, Ignatios Ikonomidis, Eva Kassi, Vaia Lambadiari, Elias Gialafos, Aikaterini Tsatsaragkou, Vasiliki-Chara Mystakidi, Konstantinos Zisimos et al.
   J. Clin. Med. 2025, 14(13), 4606; https://doi.org/10.3390/jcm14134606
   Full text available online: https://www.mdpi.com/2077-0383/14/13/4606
5. “Septic Cardiomyopathy: Difficult Definition, Challenging Diagnosis, Unclear Treatment”
   by George E. Zakynthinos, Grigorios Giamouzis, Andrew Xanthopoulos, Evangelos Oikonomou, Konstantinos Kalogeras, Nikitas Karavidas, Ilias E. Dimeas, Ioannis Gialamas, Maria Ioanna Gounaridi, Gerasimos Siasos et al.
   J. Clin. Med. 2025, 14(3), 986; https://doi.org/10.3390/jcm14030986
   Full text available online: https://www.mdpi.com/2077-0383/14/3/986
6. “The Epidemiology of Syphilis Worldwide in the Last Decade”
   by Francois Rosset, Valentina Celoria, Sergio Delmonte, Luca Mastorino, Nadia Sciamarrelli, Sara Boskovic, Simone Ribero and Pietro Quaglino
   J. Clin. Med. 2025, 14(15), 5308; https://doi.org/10.3390/jcm14155308
   Full text available online: https://www.mdpi.com/2077-0383/14/15/5308
7. “Antiphospholipid Syndrome: A Comprehensive Clinical Review”
   by Vasileios Patriarcheas, Georgios Tsamos, Dimitra Vasdeki, Elias Kotteas, Anastasios Kollias, Dimitris Nikas, Georgia Kaiafa and Evangelos Dimakakos
   J. Clin. Med. 2025, 14(3), 733; https://doi.org/10.3390/jcm14030733
   Full text available online: https://www.mdpi.com/2077-0383/14/3/733
8. “Acromegaly and Cardiovascular Disease: Associated Cardiovascular Risk Factors, Cardiovascular Prognosis, and Therapeutic Impact”
   by Pedro Iglesias
   J. Clin. Med. 2025, 14(6), 1906; https://doi.org/10.3390/jcm14061906
   Full text available online: https://www.mdpi.com/2077-0383/14/6/1906
9. “Effect of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) on Left Ventricular Mechanics in Patients Without Overt Cardiac Disease: A Systematic Review and Meta-Analysis”
   by Andrea Sonaglioni, Federica Cerini, Valeria Fagiani, Gian Luigi Nicolosi, Maria Grazia Rumi, Michele Lombardo and Paola Muti
   J. Clin. Med. 2025, 14(8), 2690; https://doi.org/10.3390/jcm14082690
   Full text available online: https://www.mdpi.com/2077-0383/14/8/2690
10. “Serum Lipids, Inflammation, and the Risk of Atrial Fibrillation: Pathophysiological Links and Clinical Evidence”
    by Alfredo Mauriello, Adriana Correra, Anna Chiara Maratea, Alfredo Caturano, Biagio Liccardo, Marco Alfonso Perrone, Antonio Giordano, Gerardo Nigro, Antonello D’Andrea and Vincenzo Russo
    J. Clin. Med. 2025, 14(5), 1652; https://doi.org/10.3390/jcm14051652
    Full text available online: https://www.mdpi.com/2077-0383/14/5/1652
11. “Emerging Therapies in Inflammatory Bowel Disease: A Comprehensive Review”
    by John K. Appiah, Umar Hayat, Nikita Garg, Richeal Asante, Evans Donneyong, Muhammad U. Haider, Pranav Patel, Zubair Khan and Ali A. Siddiqui
    J. Clin. Med. 2025, 14(17), 6119; https://doi.org/10.3390/jcm14176119
    Full text available online: https://www.mdpi.com/2077-0383/14/17/6119
12. “Lipoprotein(a) as a Stroke Biomarker: Pathophysiological Pathways and Therapeutic Implications”
    by Evangelos Panagiotopoulos, Lina Palaiodimou, Aikaterini Theodorou, Georgia Papagiannopoulou, Eleni Bakola, Maria Chondrogianni, Klearchos Psychogios, Odysseas Kargiotis, Apostolos Safouris, Charalambos Vlachopoulos et al.
    J. Clin. Med. 2025, 14(9), 2990; https://doi.org/10.3390/jcm14092990
    Full text available online: https://www.mdpi.com/2077-0383/14/9/2990
13. “Frailty in Geriatrics: A Critical Review with Content Analysis of Instruments, Overlapping Constructs, and Challenges in Diagnosis and Prognostic Precision”
    by José Fierro-Marrero, Álvaro Reina-Varona, Alba Paris-Alemany and Roy La Touche
    J. Clin. Med. 2025, 14(6), 1808; https://doi.org/10.3390/jcm14061808
    Full text available online: https://www.mdpi.com/2077-0383/14/6/1808
14. “Diagnostic and Prognostic Value of Hematological Parameters in Necrotizing Enterocolitis: A Systematic Review”
    by Rozeta Sokou, Petros Mantzios, Alexia Eleftheria Palioura, Andreas G. Tsantes, Alexandra Lianou, Daniele Piovani, Konstantina A. Tsante, Katerina Lampropoulou, Nicoletta Iacovidou and Stefanos Bonovas
    J. Clin. Med. 2025, 14(7), 2530; https://doi.org/10.3390/jcm14072530
    Full text available online: https://www.mdpi.com/2077-0383/14/7/2530