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Rom. J. Prev. Med., Volume 4, Issue 2 (June 2026) – 1 article

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Review
How Effective Is Vanilla planifolia Beyond Flavor in Protecting Against Oxidative Stress?
by Bee Ling Tan and Lee Chin Chan
Rom. J. Prev. Med. 2026, 4(2), 3; https://doi.org/10.3390/rjpm4020003 - 2 Apr 2026
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Abstract
Emerging evidence indicates that low-grade chronic systemic inflammation is a key contributor to the onset and progression of numerous chronic diseases. Vanilla planifolia, a globally valued spice recognized for its characteristic sweet aroma and flavor, is primarily derived from its beans and [...] Read more.
Emerging evidence indicates that low-grade chronic systemic inflammation is a key contributor to the onset and progression of numerous chronic diseases. Vanilla planifolia, a globally valued spice recognized for its characteristic sweet aroma and flavor, is primarily derived from its beans and widely utilized in culinary, therapeutic, and medicinal contexts. Beyond its traditional use, vanilla provides essential nutrients and bioactive compounds, including B vitamins such as vitamin B6, niacin, and riboflavin, which are integral to metabolic regulation. In addition to its applications in food and pharmaceuticals, vanilla exhibits complementary medicinal properties. Vanillin, the principal bioactive constituent of vanilla, imparts its distinctive flavor and aroma and is accompanied by other phenolic compounds with notable antioxidant activity. This review highlights the potential of vanillin as a therapeutic agent, shifting its perception from a conventional flavoring compound to a promising bioactive molecule with relevance in chronic disease prevention. Furthermore, the applications of vanillin within the food industry are discussed. Full article
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