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Organoids, Volume 3, Issue 2

June 2024 - 4 articles

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Articles (4)

  • Article
  • Open Access
2 Citations
2,123 Views
22 Pages

Single-Cell Assessment of Human Stem Cell-Derived Mesolimbic Models and Their Responses to Substances of Abuse

  • Thomas P. Rudibaugh,
  • Ryan W. Tam,
  • R. Chris Estridge,
  • Samantha R. Stuppy and
  • Albert J. Keung

20 June 2024

The mesolimbic pathway connects ventral tegmental area dopaminergic neurons and striatal medium spiny neurons, playing a critical role in reward and stress behaviors. Exposure to substances of abuse during development and adulthood has been linked to...

  • Protocol
  • Open Access
6 Citations
13,228 Views
13 Pages

Development and Optimization of a Lactate Dehydrogenase Assay Adapted to 3D Cell Cultures

  • Héloïse Castiglione,
  • Lucie Madrange,
  • Thomas Lemonnier,
  • Jean-Philippe Deslys,
  • Frank Yates and
  • Pierre-Antoine Vigneron

5 June 2024

In recent years, 3D cell culture systems have emerged as sophisticated in vitro models, providing valuable insights into human physiology and diseases. The transition from traditional 2D to advanced 3D cultures has introduced novel obstacles, complic...

  • Communication
  • Open Access
1 Citations
4,857 Views
30 Pages

Organoids, Biocybersecurity, and Cyberbiosecurity—A Light Exploration

  • Xavier Palmer,
  • Cyril Akafia,
  • Eleasa Woodson,
  • Amanda Woodson and
  • Lucas Potter

13 May 2024

Organoids present immense promise for studying organ systems and their functionality. Recently, they have become the subject of exploration outside of purely biomedical uses in multiple directions. We will explore the rapidly evolving landscape of or...

  • Review
  • Open Access
2 Citations
8,908 Views
16 Pages

Treatment of Canine Type 1 Diabetes Mellitus: The Long Road from Twice Daily Insulin Injection towards Long-Lasting Cell-Based Therapy

  • Flavia C. M. Oliveira,
  • Annemarie W. Y. Voorbij,
  • Elisa C. Pereira,
  • Leonor M. M. Alves e Almeida,
  • Geanne R. Moraes,
  • Joana T. De Oliveira,
  • Boyd H. T. Gouw,
  • Sabrina A. M. Legatti,
  • Hans S. Kooistra and
  • Bart Spee
  • + 2 authors

4 April 2024

For over 150 years, researchers have studied the (patho)physiology of the endocrine pancreas and devised treatment options for diabetes mellitus (DM). However, no cure has been developed so far. In dogs, diabetes mellitus type 1 (T1DM) is the most co...

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Organoids - ISSN 2674-1172