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Organoids, Volume 3, Issue 1

March 2024 - 5 articles

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Articles (5)

  • Protocol
  • Open Access
4 Citations
4,152 Views
13 Pages

Generation of Trophoblast Organoids from Chorionic Villus Sampling

  • Bas van Rijn,
  • Diane Van Opstal,
  • Nicole van Koetsveld,
  • Maarten Knapen,
  • Joost Gribnau and
  • Olivier Schäffers

5 March 2024

Studying human placental development and function presents significant challenges due to the inherent difficulties in obtaining and maintaining placental tissue throughout the course of an ongoing pregnancy. Here, we provide a detailed protocol for g...

  • Article
  • Open Access
2 Citations
4,745 Views
19 Pages

Analysis of Osteosarcoma Cell Lines and Patient Tissue Using a 3D In Vivo Tumor Model—Possible Effects of Punicalagin

  • Anna Rebecca Dorn,
  • Sara Neff,
  • Sophia Hupp,
  • Melissa Engelhardt,
  • Eric Pion,
  • Ulrich Lenze,
  • Carolin Knebel,
  • Anna Duprée,
  • Simone Schewe and
  • Markus Weber
  • + 7 authors

4 March 2024

Osteosarcomas are the most common primary malignant bone tumors and mostly affect children, adolescents, and young adults. Despite current treatment options such as surgery and polychemotherapy, the survival of patients with metastatic disease remain...

  • Editorial
  • Open Access
2 Citations
3,442 Views
3 Pages

20 February 2024

In this issue, we are pleased and honored to have an interview with Professor Hans Clevers, who is the Advisory Board Member of Organoids [...]

  • Article
  • Open Access
7 Citations
4,636 Views
14 Pages

Human Nasal Epithelium Organoids for Assessing Neutralizing Antibodies to a Protective SARS-CoV-2 Virus-like Particle Vaccine

  • Julio Carrera Montoya,
  • Simon Collett,
  • Daniel Fernandez Ruiz,
  • Linda Earnest,
  • Melissa A. Edeling,
  • Ashley Huey Yiing Yap,
  • Chinn Yi Wong,
  • James P. Cooney,
  • Kathryn C. Davidson and
  • Jason Roberts
  • + 14 authors

1 February 2024

Existing mRNA COVID-19 vaccines have shown efficacy in reducing severe cases and fatalities. However, their effectiveness against infection caused by emerging SARS-CoV-2 variants has waned considerably, necessitating the development of variant vaccin...

  • Feature Paper
  • Article
  • Open Access
5 Citations
4,397 Views
17 Pages

Visualization of Vascular Perfusion of Human Pancreatic Cancer Tissue in the CAM Model and Its Impact on Future Personalized Drug Testing

  • Andreas Ettner-Sitter,
  • Agata Montagner,
  • Jonas Kuenzel,
  • Kathrin Brackmann,
  • Maximilian Schäfer,
  • Robert Schober,
  • Florian Weber,
  • Thiha Aung,
  • Christina Hackl and
  • Silke Haerteis

8 January 2024

Although significant improvements have been made in the treatment of pancreatic cancer, its prognosis remains poor with an overall 5-year survival rate of less than 10%. New experimental approaches are necessary to develop novel therapeutics. In this...

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Organoids - ISSN 2674-1172