Time-Restricted Feeding and Weight Loss in Obesity: A Mini Review on the Impacts on Skeletal Muscle Mass

Round 1

Reviewer 1 Report

The topic proposed by the authors, a priori, is interesting. However, the search for this items is scarce. The studies are of short duration, with a small number of patients, practically exploratory; so, the conclusions derived from this analysis may be biased.

In addition, the body composition evaluation systems are not well indicated in the text and the values obtained, beyond the fat-free mass, are not really indicative of loss of muscle mass and function.

Overall, there is not sufficiently homogeneous material to carry out what would be considered a systematic review; therefore drawing risky conclusions at this moment.

Author Response

Dear Reviewer,

Please see the attachment.

Best regards. 

Author Response File: Author Response.docx

Reviewer 2 Report

The presented manuscript is interesting and I have no objections to this review. In my opinion, the main subject of manuscript is discussed in relatively detail. However, I lacked indication regarding the composition of the diet, which contributes the least to the loss of muscle mass during use TRF. The Authors should  added a few indication. There is also no translation of the abbreviation IF (p 2, line 72).

Best regards

Author Response

Dear Reviewer,

Please see the attachment.

Best regards.

Author Response File: Author Response.docx

Round 2

Reviewer 1 Report

The changes made by the authors show sufficient explanations to describe the paucity of robust results to suggest poor protein commitment with TRF diets.

I consider it suitable to be published in this journal.