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Transplantology, Volume 6, Issue 3

2025 September - 9 articles

Cover Story: Six years ago, the European–Mediterranean Postgraduate Training Program on Organ Donation and Transplantation (EMPODaT) was implemented in six universities from Egypt, Lebanon, and Morocco. This study evaluates the impact of training on healthcare professionals, their career development, and institutional practices. Most postgraduates remain active in the field of organ donation and transplantation, many achieved leadership positions, and hospitals report improvements in policies and clinical practices. The program strengthened regional collaboration and highlighted the crucial role of official and institutional support for sustainable changes. EMPODaT is an example of how well-structured, context-specific postgraduate education can build capacities and foster cultural and systemic transformations in organ donation and transplantation. View this paper
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Articles (9)

  • Article
  • Open Access
1,462 Views
13 Pages
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Assessing Short- and Medium-Term Outcomes of Lung Transplantation in Elderly Recipients: A Comparative Age-Based Analysis

  • Chiara Catelli,
  • Andrea Lloret Madrid,
  • David Bennett,
  • Miriana D’Alessandro,
  • Marco Guerrieri,
  • Marianna Rizzo,
  • Daniele Marianello,
  • Antonella Fossi,
  • Piero Paladini and
  • Luca Luzzi
  • + 1 author
Transplantology2025, 6(3), 28;https://doi.org/10.3390/transplantology6030028

17 September 2025

Background/Objectives: This study aims to analyze the short- and medium-term outcomes of lung transplantation (LT) in recipients aged 65 years and older, comparing them with those of younger individuals. The primary endpoints were 90-day and 1-year s...

Full Article
  • Case Report
  • Open Access
979 Views
9 Pages
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Calycovesicostomy, Ureterocalycostomy, and Ileocalycostomy: Rare Reconstructive Options for Transplant Ureteral Strictures

  • Talal Al-Qaoud,
  • Rawan Al-Yousef,
  • Basma Behbehani and
  • Abdullatif Al-Terki
Transplantology2025, 6(3), 27;https://doi.org/10.3390/transplantology6030027

4 September 2025

Background: Transplant ureteral stricture (TUS) reconstruction remains a significant challenge in renal transplantation, particularly when conventional access to the transplant ureter and renal pelvis is not feasible. This report presents two rare an...

Full Article
  • Feature Paper
  • Article
  • Open Access
1,581 Views
15 Pages
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Impact of the European–Mediterranean Postgraduate Program on Organ Donation and Transplantation (EMPODaT): A Survey Analysis at 6 Years

  • Chloe Ballesté,
  • Seow-Huey Choy,
  • Mauricio Galvao,
  • Brian Alvarez,
  • Carmen Blanco,
  • Joaquim Albiol,
  • Patricia Peralta,
  • David Paredes,
  • Martí Manyalich and
  • Ricard Valero
Transplantology2025, 6(3), 26;https://doi.org/10.3390/transplantology6030026

28 August 2025

Background/Objectives: To evaluate the impact of the European–Mediterranean Postgraduate Program on Organ Donation and Transplantation (EMPODaT) on organ donation and transplantation (ODT) at 6 years. Methods: EMPODaT is a Trans-European Mobili...

Full Article
  • Case Report
  • Open Access
6,836 Views
10 Pages
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Challenging the Dogma: Reversal of End-Stage Liver Fibrosis with Tirzepatide in MASH Cirrhosis

  • Thuy-Duyen Nguyen,
  • Dora Lam-Himlin,
  • Blanca Lizaola-Mayo and
  • David Chascsa
Transplantology2025, 6(3), 25;https://doi.org/10.3390/transplantology6030025

20 August 2025

Background/Objectives: The growing prevalence of metabolic-associated steatotic liver disease (MASLD)/metabolic-associated steatohepatitis (MASH) is forecasted to be over 55% by 2040, representing a significant driver of cirrhosis and highlighting de...

Full Article
  • Case Report
  • Open Access
1,861 Views
11 Pages
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Biopsy-Proven Solid Organ Transplant Graft-Versus-Host Disease (SOT-GVHD) Involving the Skin, Liver, and Bone Marrow in a Simultaneous Kidney-Pancreas Transplant Recipient

  • Reza Rahimi Shahmirzadi,
  • Danielle Ouellette,
  • Martin Igbokwe,
  • Alp Sener,
  • Manal Y. Gabril,
  • Subrata Chakrabarti,
  • Uday Deotare and
  • Lili Ataie
Transplantology2025, 6(3), 24;https://doi.org/10.3390/transplantology6030024

12 August 2025

Background: Graft-versus-host disease (GVHD) is a rare but serious complication following solid organ transplantation (SOT), particularly in transplants involving organs with a high volume of passenger donor T-lymphocytes. This case highlights the cl...

Full Article
  • Review
  • Open Access
5 Citations
4,719 Views
20 Pages
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AI and Machine Learning in Transplantation

  • Kavyesh Vivek and
  • Vassilios Papalois
Transplantology2025, 6(3), 23;https://doi.org/10.3390/transplantology6030023

30 July 2025

Artificial Intelligence (AI) and machine learning (ML) are increasingly being applied across the transplantation care pathway, supporting tasks such as donor–recipient matching, immunological risk stratification, early detection of graft dysfun...

Full Article
  • Article
  • Open Access
2 Citations
2,249 Views
12 Pages
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Mental Health Support for Heart Transplant Recipients and Candidates: Nurturing Well-Being Beyond Surgery

  • Lorenzo Giovannico,
  • Valeria Ladisa,
  • Simona De Santis,
  • Giuseppe Fischetti,
  • Domenico Parigino,
  • Luca Savino,
  • Federica Mazzone,
  • Nicola Di Bari,
  • Massimo Padalino and
  • Tomaso Bottio
Transplantology2025, 6(3), 22;https://doi.org/10.3390/transplantology6030022

30 July 2025

Background/Objectives: Heart transplantation is a life-saving procedure for patients with end-stage heart failure, yet it involves significant psychological and emotional challenges throughout its various stages. International guidelines recommend a...

Full Article
  • Article
  • Open Access
1,317 Views
14 Pages
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Outcomes Following Donation After Brain Death and Donation After Circulatory Death Liver Transplantation in Patients with Primary Sclerosing Cholangitis

  • Kevin Verhoeff,
  • Uzair Jogiat,
  • Alessandro Parente,
  • Blaire Anderson,
  • Khaled Dajani,
  • David L. Bigam and
  • A. M. James Shapiro
Transplantology2025, 6(3), 21;https://doi.org/10.3390/transplantology6030021

18 July 2025

Background: Primary sclerosing cholangitis (PSC) accounts for 10–15% of liver transplants but is the leading cause of retransplant. This study evaluates whether PSC patients have different survival and graft outcomes when receiving grafts from...

Full Article
  • Article
  • Open Access
1,457 Views
17 Pages
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Urinary Mitochondrial DNA Is Related to Allograft Function in Living Donor Kidney Transplantation—An Observational Study of the VAPOR-1 Cohort

  • Lucas Gartzke,
  • Julia Huisman,
  • Nora Spraakman,
  • Fernanda Lira Chavez,
  • Michel Struys,
  • Henri Leuvenink,
  • Robert Henning and
  • Gertrude Nieuwenhuijs-Moeke
Transplantology2025, 6(3), 20;https://doi.org/10.3390/transplantology6030020

26 June 2025

Background: Ischemia–reperfusion injury (IRI) is a key contributor to graft dysfunction in kidney transplantation. Cell-free mitochondrial DNA (mtDNA) is increasingly recognized as a damage-associated molecular pattern (DAMP) and biomarker in I...

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