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Sinusitis, Volume 3, Issue 2

2018 June - 4 articles

Cover Story: Bitter and sweet taste receptors exist in the upper airway, where they play key roles in antimicrobial innate immune defense. Genetic variations in taste receptor functionality are related to disease status and disease severity in chronic rhinosinusitis. Taste agonists can potentially serve as diagnostic and therapeutic agents for a variety of airway diseases. View this paper.
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Articles (4)

  • Review
  • Open Access
1 Citations
7,651 Views
10 Pages

The Role of Taste Receptors in Airway Innate Immune Defense

  • Alan D. Workman,
  • Neil N. Patel,
  • Ryan M. Carey,
  • Edward C. Kuan and
  • Noam A. Cohen

Bitter (T2R) and sweet (T1R) taste receptors are expressed in the upper airway, where they play key roles in antimicrobial innate immune defense. Bitter bacterial products are detected by taste receptors on ciliated cells and solitary chemosensory ce...

  • Article
  • Open Access
7,781 Views
8 Pages

Complications of Short-Course Oral Corticosteroids for Eosinophilic Chronic Rhinosinusitis during Long-Term Follow-Up

  • Remi Motegi,
  • Shin Ito,
  • Hirotomo Homma,
  • Noritsugu Ono,
  • Hiroko Okada,
  • Yoshinobu Kidokoro,
  • Akihito Shiozawa and
  • Katsuhisa Ikeda

The literature strongly recommends the use of oral corticosteroids in the management of patients with eosinophilic chronic rhinosinusitis (CRS) with nasal polyps. Although potential complications associated with the long-term use of oral corticostero...

  • Review
  • Open Access
1 Citations
6,297 Views
5 Pages

Pediatric chronic rhinosinusitis is a common condition amongst pediatric patients. Despite its prevalence, debate continues regarding the best treatment strategies. The current paper examines the literature as it pertains to the surgical management o...

  • Review
  • Open Access
2 Citations
6,115 Views
8 Pages

Rhinosinutis and Asthma in Children

  • Amelia Licari,
  • Ilaria Brambilla,
  • Riccardo Castagnoli,
  • Alessia Marseglia,
  • Valeria Paganelli,
  • Thomas Foiadelli and
  • Gian Luigi Marseglia

Rhinosinusitis and asthma are two comorbid conditions that lead to pathological and clinical diseases affecting the respiratory tract. They are connected by significant anatomical, epidemiological, pathophysiological, and clinical evidence, and also...

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Sinusitis - ISSN 2673-351X